Genetic Predisposition to Transplacentally Induced Renal Cell Carcinomas in the Eker Rat

Cancer Research

Volumn 53, Issue 24, 1993, Pages 5856-5858

  Hino, Okio ^a   Mitani, Hiroaki ^b   Knudson, Alfred G ^b  

^a CANCER INSTITUTE   (Japan)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHYLNITROSOUREA;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE MUTATION; GENETIC PREDISPOSITION; HISTOLOGY; KIDNEY CARCINOMA; NEPHROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; CARCINOMA, RENAL CELL; ETHYLNITROSOUREA; FEMALE; FETUS; KIDNEY NEOPLASMS; MALE; MUTATION; NEPHROBLASTOMA; ONCOGENES; PREGNANCY; RATS; RATS, MUTANT STRAINS; SUPPORT, NON-U.S. GOV'T;

EID: 0027139911     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Knudson, A. G. A two-mutation model for human cancer. In: G. Klein, (ed.), Advances in Viral Oncology, pp. 1-17. New York: Raven Press, 1987.
2. Hara, H. Miyao, M. Moriki, T. Kutsukake, F. and Yamane, T. Histological and ultrastructural studies of nephroblastoma in rats induced transplacentally by ethylnitrosourea. Acta Pathol. Jpn. 32: 385-398, 1982.
3. Hard, G. C. Differential renal tumor response to N-ethylnitrosourea and dimethylni-trosamine in the Nb rat: basis for a new rodent model of nephroblastoma. Carcinogenesis (Lond.), 6: 1551-1558, 1985.
4. Eker, R. and Mossige, J. A dominant gene for renal adenomas in the rat. Nature (Lond.), 189: 858-859, 1961.
5. Everitt, J. I. Goldsworthy, T. L. Wolf, D. C. and Walker, C. L. Hereditary renal cell carcinoma in the Eker rat: a rodent familial cancer syndrome. J. Urol. 148: 1932-1936, 1992.
6. Hino, O. Klein-Szanto, A. J. P. Freed, J. J. Testa, J. R. Brown, D. Q. Vilensky, M. Yeung, R. S. Tartof, K. D. and Knudson, A. G. Spontaneous and radiation-induced. renal tumors in the Eker rat model of dominantly inherited cancer. Proc. Natl. Acad. Sci. USA, 90: 327-331, 1993.
7. Yeung, R. S. Buetow, K. H. Testa, J. R. and Knudson, A. G. Susceptibility to renal carcinoma in the Eker rat involves a tumor suppressor gene on chromosome 10. Proc. Natl. Acad. Sci. USA, 90: 8038-8042, 1993.
8. Hino, O. Mitani, H. Nishizawa, M. Katsuyama, H. Kobayashi, E. and Hirayama, Y. A novel renal cell carcinoma susceptibility gene maps on chromosome 10 in the Eker rat. Jpn. J. Cancer Res. 84: 1106-1109, 1993.
9. Hino, O. Testa, J. R. Buetow, K. H. Taguchi, T. Zhou, J.-Y. Bremer, M. Bruzel, A. Yeung, R. Levan, G. Levan, K. K. Knudson, A. G. and Tartof, K. D. Universal mapping probes and origin of human chromosome 3. Proc. Natl. Acad. Sci. USA, 90: 730-734, 1993.
10. Yamakawa, K. Morita, R. Takahashi, E. Hon, T. Ishikawa, J. and Nakamura, Y. A detailed deletion mapping of the short arm of chromosome 3 in sporadic renal cell carcinoma. Cancer Res. 51: 4707-4711, 1991.
11. Latif, F. L. Tory, K. Gnarra, J. Yao, M. Duh, F.-M. Orcutt, M. L. Stackhouse, T. Kuzumin, I. Modi, W. Geil, L. Schmidt, L. Zhou, F. Li, H. Wei, M. H. Chen, F. Glenn, G. Choyke, P. Walther, M. M. Weng, Y. Duan, D.S. R. Dean, M. Glavac, D. Richards, F. M. Crossey, P. A. Ferguson-Smith, M. A. Paslier, D. L. Chumakov, I. Cohen, D. Chinault, A. C. Maher, E. R. Linehan, W. M. Zbar, B. and Lerman, M. I. Identification of the von Hippel-Lindau Disease tumor suppressor gene. Science (Washington DC), 260: 1317-1320, 1993.
12. Yeung, R. S. Hino, O. Vilensky, M. Buetow, K. Szpirer, C. Szpirer, J. Levan, K. K. Levan, G. and Knudson, A. G. Assignment of 22 gene loci in the rat by somatic hybrid and linkage analysis. Mamm. Genome, in press, 1993.
13. Sharma, P. M. Yang, X. Bowman, M. Roberts, V. and Sukumar, S. Molecular cloning of rat Wilms' tumor complementary DNA and a study of messenger RNA expression in the urogenital system and the brain. Cancer Res. 52: 6407-6412, 1992.
14. Saxen, L. Organogenesis of the Kidney, p. 173. Cambridge, England:Cambridge University Press, 1987.
15. Chailler, P. and Briere, N. Integration of proliferation and differentiation phenomena during rodent kidney ontogeny. Growth Dev. Aging, 55: 11-18, 1991.
16. Witzgall, R. O'Leary, E. Gessner, R. Ouellette, A. J. and Bonventre, J. V. Kid-1, a putative renal transcription factor: regulation during ontogeny and in response to ischemia and toxic injury. Mol. Cell. Biol. 13: 1933-1942, 1993.
17. Walker, C. Goldsworthy, T. L. Wolf, D. C. and Everitt, J. Predisposition to renal cell carcinoma due to alteration of a cancer susceptibility gene. Science (Washington DC), 255: 1693-1695, 1992.