Transformation of Heterocyclic Reversible Monoamine Oxidase-B Inactivators into Irreversible Inactivators by N-Methylation

Journal of Medicinal Chemistry

Volumn 36, Issue 23, 1993, Pages 3606-3610

  Ding, Charles Z ^a,b   Silverman, Richard B ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALMOXATONE; MONOAMINE OXIDASE INHIBITOR; OXAZOLIDINONE DERIVATIVE;

ARTICLE; DEPRESSION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INACTIVATION; PARKINSON DISEASE; STRUCTURE ACTIVITY RELATION;

ANIMAL; BINDING SITES; CATTLE; ENZYME ACTIVATION; ENZYME REACTIVATORS; FURANS; KINETICS; LIVER; METHYLATION; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; OXAZOLES; PYRROLIDINONES; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0027137441     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00075a015     Document Type: Article

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