Immunohistochemical location of prothymosin alpha in regenerating human hepatocytes and hepatocellular carcinomas

Virchows Archiv A Pathological Anatomy and Histopathology

Volumn 423, Issue 6, 1993, Pages 449-452

  Fraga, Máximo ^a   García Caballero, Tomás ^a   Domínguez, Fernando ^a   Pérez Becerra, Eugenio ^a   Beiras, Andrés ^a   Forteza, Jerónimo ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Cell proliferation; Chronic hepatitis; Cirrhosis; Hepatocarcinoma; Prothymosin alpha

Indexed keywords

CYCLINE; PROTHYMOSIN ALPHA;

ARTICLE; BILE DUCT; CELL NUCLEUS; CELL PROLIFERATION; CELL REGENERATION; CELLULAR DISTRIBUTION; CHRONIC HEPATITIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LIVER CELL; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; NUCLEOLUS; PRIORITY JOURNAL;

CARCINOMA, HEPATOCELLULAR; CELL DIVISION; COMPARATIVE STUDY; HEPATITIS, CHRONIC; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CIRRHOSIS; LIVER NEOPLASMS; NUCLEAR PROTEINS; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN PRECURSORS; SUPPORT, NON-U.S. GOV'T; THYMOSIN;

EID: 0027137089     PISSN: 01747398     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/BF01606534     Document Type: Article

References (30)

1. Aberrant cytoplasmic expression of proliferating cell nuclear antigen in Hodgkin's disease
2. Key enzymes of carbohydrate metabolism as targets of the 11.5-kDa Zn2+-binding protein (parathymosin)
3. Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ
4. Expression of the rat prothymosin α gene during T-lymphocyte proliferation and liver regeneration
5. Prothymosin alpha and parathymosin: mRNA and polypeptide levels in rodent tissues
6. Tissue specific and differential expression of prothymosin alpha gene during rat development
7. Isolation and partial characterization of prothymosin alpha from porcine tissues
8. The MYC protein activates transcription of the alpha prothymosin gene
9. The human prothymosin alpha gene is polymorphic and induced upon growth stimulation: evidence using a cloned cDNA
10. Nuclear localization of parathymosin in rat and human hepatocytes. A light and ultrastructural study
11. Isolation of peptides from calf thymus
12. Prothymosin alpha: isolation and properties of the major immunoreactive form of thymosin alpha 1 in rat thymus
13. Distribution of prothymosin alpha in rat tissues
14. Inhibition of cellular proliferation by antisense oligodeoxynucleotides to PCNA/cyclin
15. Analysis of proliferating hepatocytes using a monoclonal antibody against proliferating cell nuclear antigen/cyclin in embedded tissues from various liver diseases fixed in formaldehyde
16. Immunocytochemical identification of proliferative hepatocytes using monoclonal antibody to proliferating cell nuclear antigen (PCNA/cyclin). Comparison with immunocytochemical staining for DNA polymerase-alpha
17. Detection of proliferating hepatocytes by immunohistochemical staining for proliferating cell nuclear antigen (PCNA) in patients with acute hepatic failure
18. Current status of thymosin research: evidence for the existence of a family of thymic factors that control T-cell maturation
19. Prothymosin alpha is an evolutionary conserved protein covalently linked to a small RNA
20. Autoantibody to a nuclear antigen in proliferating cells
21. Biochemical identification of thymosin alpha-1: its phylogenetic distribution and evolutionary implications
22. Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein
23. Prothymosin alpha expression is associated to cell division in rat testis
24. Cellular distribution of prothymosin alpha and parathymosin in rat thymus and spleen
25. Prothymosin-alpha antisense oligomers inhibit myeloma cell division
26. Identification and fine structure of proliferating hepatocytes in malignant and nonmalignant liver diseases by use of a monoclonal antibody against DNA polymerase alpha
27. Effects of tissue fixation and processing on proliferating cell nuclear antigen (PCNA) immunohistochemistry
28. Cell proliferative activity in adenomatous hyperplasia of the liver and small hepatocellular carcinoma. An immunohistochemical study demonstrating proliferating cell nuclear antigen
29. Prothymosin a is not a nuclear polypeptide
30. Thymosins, lymphokines, and the immunology of aging