A knowledge base for predicting protein localization sites in eukaryotic cells

Genomics

Volumn 14, Issue 4, 1992, Pages 897-911

  Nakai, Kenta ^a   Kanehisa, Minoru ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; ARTIFICIAL INTELLIGENCE; AUTOMATION; CELLULAR DISTRIBUTION; EXPERT SYSTEM; GENETIC ANALYSIS; HUMAN; NONHUMAN; PLANT CELL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

ALGORITHMS; ANIMAL; CELL MEMBRANE; EXPERT SYSTEMS; GENOMIC LIBRARY; LIPIDS; PLANTS; PROTEINS; SUPPORT, NON-U.S. GOV'T;

ANIMALIA; EUKARYOTA;

EID: 0027105007     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/S0888-7543(05)80111-9     Document Type: Article

References (64)

1. Sequence identification of 2,375 human brain genes
2. Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria
3. Generation of a lysosomal enzyme targeting signal in the secretory protein pepsinogen
4. Protein sequence database
5. A common peptide stretch among enzymes localized to the Golgi apparatus: Structural similarity of Golgi-associated glycosyltransferases
6. How proteins get into microbodies (peroxisomes, glyoxysomes, glycosomes)
7. NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor
8. Short peptide domains target proteins to plant vacuoles
9. Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis
10. Glycolipid anchoring of plasma membrane proteins
11. The endoplasmic reticulum retention signal of the E3/19K protein of adenovirus-2 is microtubule binding
12. Three-dimensional structure of membrane and surface proteins
13. Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures
14. A conserved cleavage-site motif in chloroplast transit peptides
15. Cleavage-site motifs in mitochondrial targeting peptides
16. A conserved tripeptide sorts proteins to peroxisomes
17. Peroxisomal protein import is conserved between yeast, plants, insects and mammals
18. The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal
19. ras to the plasma membrane
20. The transit peptide of a chloroplast thylakoid membrane protein is functionally equivalent to a stromal-targeting sequence
21. Protein sorting to mitochondria: Evolutionary conservations of folding and assembly
22. Predicting the orientation of eukaryotic membrane spanning proteins
23. 5 in lipids by fourier-transform infrared spectroscopy
24. The CaaX motif of lamin A functions in conjunction with the nuclear localization signal to target assembly to the nuclear envelope
25. Prediction of leader peptide cleavage sites for polypeptides of the thylakoid lumen
26. Cytoplasmic anchoring proteins and the control of nuclear localization
27. Golgi localization signals
28. Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum
29. Chloroplastic precursors and their transport across the envelope membranes
30. The detection and classification of membrane-spanning proteins
31. A new class of lysosomal/vacuolar protein sorting signals
32. The biogenesis of lysosomes
33. A specific transmembrane domain of a coronavirus E1 glycoprotein is required for its retention in the Golgi region
34. Posttranslational modification of proteins by isoprenoids in mammalian cells
35. On the predictive recognition of signal peptide sequences
36. The fats of life: The importance and function of protein acylation
37. Prediction of in-vivo modification sites of proteins from their primary structures
38. Expert system for predicting protein localization sites in Gram-negative bacteria
39. Topogenesis of peroxisomal proteins
40. Topology of Eukaryotic type II membrane proteins: Importance of N-terminal positively charged residues flanking the hydrophobic domain
41. The retention signal for soluble proteins of the enndoplasmic reticulum
42. Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi
43. A Common RNA Recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein
44. v-src: A model for myristylated tyrosine protein kinases
45. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
46. Protein targeting to the yeast vacuole
47. A novel secretory pathway for interleukin-1β, a protein lacking a signal sequence
48. Fatty acylation of proteins
49. How proteins enter the nucleus
50. Polarized sorting in epithelia
51. The structure and insertion of integral proteins in membranes
52. The biology and enzymology of eukaryotic protein acylation
53. Characterization of nuclear localizing sequences derived from yeast ribosomal protein L29
54. Naming a targeting signal
55. Protein translocation across membranes
56. A new method for predicting signal sequence cleavage sites
57. Topogenic signals in integral membrane proteins
58. Domain structure of mitochondrial and chloroplast targeting peptides
59. Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail
60. A novel pathway of import of α-mannosidase, a marker enzyme of vacuolar membrane, in Saccharomyces cerevisiae
61. Nuclear transport of adenovirus DNA polymerase is facilitated by interaction with preterminal protein