The effects of Danshen (Salvia miltiorrhiza) on pharmacokinetics and pharmacodynamics of warfarin in rats

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 17, Issue 4, 1992, Pages 257-262

  Lo, A C T ^a   Chan, K ^a   Yeung, J H K ^a   Woo, K S ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

Danshen; HPLC; prothrombin time; warfarin

Indexed keywords

WARFARIN;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG POTENTIATION; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHARMACODYNAMICS; PRIORITY JOURNAL; PROTHROMBIN TIME; RAT; SALVIA MILTIORRHIZA;

ANIMAL; DRUG COMBINATIONS; DRUG INTERACTIONS; DRUGS, CHINESE HERBAL; MALE; PHENANTHROLINES; PROTHROMBIN TIME; RATS; RATS, SPRAGUE-DAWLEY; SUPPORT, NON-U.S. GOV'T; WARFARIN;

EID: 0027089785     PISSN: 03787966     EISSN: 21070180     Source Type: Journal    
DOI: 10.1007/BF03190157     Document Type: Article

References (8)

1. The effect of hepatic uptake on the disappearance of warfarin from the plasma of rats: A kinetic analysis
2. Studies on cardiovascular actions of Salvia miltiorrhiza
3. Cardiovascular pharmacology of Panax Notoginseng (Burk) F.H. Chen and Salvia miltiorrhiza
4. Effect of salvianolic acid A., a depside from roots of Salvia miltiorrhiza, on gastric H+, K+-ATPase
5. Determination of warfarin in human plasma by high performance liquid chromatography
6. Warfarin: metabolism and mode of action