The β-PDGF receptor induces neuronal differentiation of PC12 cells

Molecular Biology of the Cell

Volumn 3, Issue 5, 1992, Pages 545-553

  Heasley, Lynn E ^a,b   Johnson, Gary L ^a,b  

^a NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; EPIDERMAL GROWTH FACTOR; MICROTUBULE ASSOCIATED PROTEIN; NERVE GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FAST PROTEIN LIQUID CHROMATOGRAPHY; IMMUNOBLOTTING; NERVE CELL DIFFERENTIATION; NONHUMAN; PHEOCHROMOCYTOMA CELL; RAT;

ANIMAL; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIFFERENTIATION; GROWTH SUBSTANCES; NEURONS; PC12 CELLS; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASES; RECEPTORS, CELL SURFACE; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TYROSINE;

EID: 0027082766     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.3.5.545     Document Type: Article

References (33)

1. Ahn, N.G., Seger, R., Bratlien, R.L., Diltz, C.D., Tonks, N.K., and Krebs, E.G. (1991). Multiple components in an epidermal growth factor-stimulated protein kinase cascade. J. Biol. Chem. 266, 4220-4227.
2. Ahn, N.G., Weiel, J.E., Chan, C.P., and Krebs, E.G. (1990). Identification of multiple epidermal growth factor-stimulated protein serine/ threonine kinases from Swiss 3T3 cells. J. Biol. Chem. 265, 11487-11494.
3. Alema, S., Casalbore, P., Agostini, E., and Tato, F. (1985). Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene. Nature 316, 557-559.
4. Anderson, N.G., Maller, J.L., Tonks, N.K., and Sturgill, T.W. (1990). Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase. Nature 343, 651-653.
5. Boulton, T.G., Nye, S.H., Robbins, D.J., Ip, N.Y., Radziejewska, E., Morgenbesser, S.D., DePinho, R.A., Panayotatos, N., Cobb, M.H., and Yancopoulos, G.D. (1991). ERKs: a family of protein-serine/ threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF. Cell 65, 663-675.
6. Cobb, M.H., Boulton, T.G., and Robbins, D.J. (1991). Extracellular signal-regulated kinases: ERKs in progress. Cell Regulation 2, 965-978.
7. Courchesne, W.E., Kunisawa, R., and Thorner, J. (1989). A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae. Cell 58, 1107-1119.
8. Dahmer, M.K., Ji, L., and Perlman, R.L. (1989). Characterization of insulin-like growth factor-I receptors in PC12 pheochromocytoma cells and bovine adrenal medulla. J. Neurochem. 53, 1036-1042.
9. Dahmer, M.K., and Perlman, R.L. (1988). Insulin and insulin-like growth factors stimulate DNA synthesis in PC12 pheochromocytoma cells. Endocrinology 122, 2109-2113.
10. +/CDC28-related kinase required for the transition from mitosis into conjugation. Cell 60, 649-664.
11. Erickson, A.K., Payne, D.M., Martino, P.A., Rossomando, A.J., Shabanowitz, J., Weber, M.J., Hunt, D.F., and Strurgill, T.W. (1990). Identification by mass spectrometry of threonine 97 in bovine myelin basic protein as a specific phosphorylation site for mitogen-activated protein kinase. J. Biol. Chem. 265, 19728-19735.
12. Gomez, N., Tonks, N.K., Morrison, C., Harmar, T., and Cohen, P. (1990). Evidence for communication between nerve growth factor and protein tyrosine phosphorylation. FEBS Lett. 271, 119-122.
13. Gotoh, Y., Nishida, E., Yamashita, T., Hoshi, M., Kawakami, M., and Sakai, H. (1990). Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Eur. J. Biochem. 193, 661-669.
14. Greene, L.A., and Tischler, A.S. (1976). Establishment of a norad-renergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA 73, 2424-2428.
15. Heasley, L.E., Benedict, S., Gleavy, J., and Johnson, G.L. (1991). Requirement of the adenovirus E1A transformation domain 1 for inhibition of PC12 cell neuronal differentiation. Cell Regulation 2, 479-489.
16. Heasley, L.E., and Johnson, G.L. (1989a). Detection of nerve growth factor and epidermal growth factor-regulated protein kinases in PC12 cells with synthetic peptide substrates. Molec. Pharmacol. 35, 331-338.
17. Heasley, L.E., and Johnson, G.L. (1989b). Regulation of protein kinase C by nerve growth factor, epidermal growth factor, and phorbol esters in PC12 pheochromocytoma cells. J. Biol. Chem. 264, 8646-8652.
18. Hempstead, B.L., Martin-Zanca, D., Kaplan, D.R., Parada, L.F., and Chao, M.V. (1991). High-affinity NGF binding requires co-expression of the Trk proto-oncogene and the low-affinity NGF receptor. Nature 350, 678-683.
19. Huff, K., End, D., and Guroff, G. (1981). Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor. J. Cell Biol. 88, 189-198.
20. Kaplan, D.R., Martin-Zanca, D., and Parada, L.F. (1991). Tyrosine phosphorylation and tyrosine kinase activity of the Trk proto-oncogene product induced by NGF. Nature 350, 158-160.
21. Kazlauskas, A., Durden, D.L., and Cooper, J.A. (1991). Functions of the major tyrosine phosphorylation site of the PDGF receptor β subunit. Cell Regulation 2, 413-425.
22. Kirschmeier, P.T., Housey, G.M., Johnson, M.D., Perkins, A.S., and Weinstein, I.B. (1988). Construction and characterization of a retroviral vector demonstrating efficient expression of cloned cDNA sequences. DNA 7, 219-225.
23. Klein, R., Jung, S., Nanduri, V., O'Rourke, E., and Barbacid, M. (1991). The Trk proto-oncogene encodes a receptor for nerve growth factor. Cell 65, 189-197.
24. Lee, P.L., Johnson, D.E., Cousens, L.S., Fried, V.A., and Williams, L.T. (1989). Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor. Science 24, 57-60.
25. Lev, S., Givol, D., and Yarden, Y. (1991). A specific combination of substrates is involved in signal transduction by the kit-encoded receptor. EMBO J. 10, 647-654.
26. Maher, P.A. (1988). Nerve growth factor induces protein-tyrosine phosphorylation. Proc. Natl. Acad. Sci. USA 85, 6788-6791.
27. Markowitz, D., Goff, S., and Bank, A. (1988). A safe packaging line for gene transfer: separating viral genes on two different plasmids. J. Virol. 62, 1120-1124.
28. Maruyama, K., Schiavi, S.C., Huse, W., Johnson, G.L., and Ruley, H.E. (1987). myc and E1A oncogenes alter the responses of PC12 cells to nerve growth factor and block differentiation. Oncogene 4, 361-367.
29. Miller, A.D., and Rosman, G.J. (1989). Improved retroviral vectors for gene transfer and expression. BioTechniques 7, 980-990.
30. Tsao, H., Aletta, J.M., and Greene, L.A. (1990). Nerve growth factor and fibroblast growth factor selectively activate a protein kinase that phosphorylates high molecular weight microtubule-associated proteins. J. Biol. Chem. 265, 15471-15480.
31. Ullrich, A., and Schlessinger, J. (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.
32. Yaciuk, P., Carter, M.C., Pipas, J.M., and Moran, E. (1991). Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products. Mol. Cell. Biol. 11, 2116-2124.
33. Van, H., Schlessinger, J., and Chao, M.V. (1991). Chimeric NGF-EGF receptors define domains responsible for neuronal differentiation. Science 252, 561-563.