Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis

Nucleic Acids Research

Volumn 20, Issue 24, 1992, Pages 6613-6619

  Legault, Pascale ^a   Herschlag, Daniel ^a   Celander, Daniel W ^a   Cech, Thomas R ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOCIDAE; TETRAHYMENA;

EDETATE IRON; GUANOSINE; MAGNESIUM ION; RIBOZYME;

ARTICLE; BINDING SITE; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STABILITY; GENE MUTATION; HYDROLYSIS; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; RNA STRUCTURE; TEMPERATURE; TETRAHYMENA;

ANIMAL; BASE SEQUENCE; BINDING SITES; CALORIMETRY; GUANOSINE; HYDROGEN BONDING; INTRONS; KINETICS; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; OLIGORIBONUCLEOTIDES; RNA, CATALYTIC; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TETRAHYMENA THERMOPHILA;

EID: 0027078053     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/20.24.6613     Document Type: Article

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