Transferrin microheterogeneity in rheumatoid arthritis - Relation with disease activity and anemia of chronic disease

Rheumatology International

Volumn 12, Issue 5, 1992, Pages 195-199

  Feelders, R A ^a   Vreugdenhil, G ^b   de Jong, G ^c   Swaak, A J G ^c,d   Van Eijk, H G ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d CENTRAL LABORATORY   (Netherlands)

Author keywords

Acute phase response; Disease activity; Erythroblast iron availability; Glycosylation; Transferrin

Indexed keywords

C REACTIVE PROTEIN; COMPLEMENT COMPONENT C1Q; FERRITIN; GLYCAN; IRON; TRANSFERRIN;

ACUTE PHASE RESPONSE; ADULT; AGED; ANEMIA; ARTICLE; BONE MARROW BIOPSY; CHRONIC DISEASE; CLINICAL ARTICLE; COMPLEMENT FIXATION TEST; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE DURATION; ERYTHROBLAST; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FERRITIN BLOOD LEVEL; HEMATOCRIT; HEMOGLOBIN DETERMINATION; HUMAN; IRON BLOOD LEVEL; IRON DEFICIENCY; ISOELECTRIC FOCUSING; MALE; MEAN CORPUSCULAR VOLUME; NORMAL HUMAN; PROTEIN ANALYSIS; PROTEIN GLYCOSYLATION; PROTEIN POLYMORPHISM; PROTEIN SYNTHESIS; RETICULOCYTE COUNT; RHEUMATOID ARTHRITIS; SERUM; SIALYLATION;

ANEMIA; ARTHRITIS, RHEUMATOID; BLOOD SEDIMENTATION; C-REACTIVE PROTEIN; HUMAN; IRON; ISOMERISM; MIDDLE AGE; N-ACETYLNEURAMINIC ACID; SIALIC ACIDS; TRANSFERRIN;

EID: 0027076354     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/BF00302152     Document Type: Article

References (47)

1. Hematologic abnormalities in rheumatoid arthritis
2. Anemia in rheumatoid arthritis. The role of iron, vitamin B12 and folic acid deficiency and erythropoietin responsiveness
3. Serum ferritin and the assessment of iron deficiency in rheumatoid arthritis
4. Anemia of chronic disease: diagnostic significance of erythrocyte and serological parameters in iron deficient rheumatoid arthritis patients
5. The anemia of chronic disorders
6. Mechanisms of anemia in rheumatoid arthritis: demonstration of raised interleukine-1β concentrations in anemic patients and of interleukine-1 mediated suppression of normal erythropoiesis and proliferation of human erythroleukemia (H.E.L.) cells in vitro
7. mechanisms of erythroid suppression in the anemia of chronic disease
8. Anemia of chronic disease in rheumatoid arthritis: raised serum interleukine-6 (IL-6) levels and effects of IL-6 and anti-IL-6 on in vitro erythropoiesis
9. Serum erythropoietin in rheumatoid arthritis and other inflammatory athritides: relationship to anemia and the effect of anti-inflammatory treatment
10. The measurement of reticuloendothelial iron release using iron dextran
11. A method for the investigation of reticuloendothelial iron kinetics in man
12. Anaemia in rheumatoid arthritis: pathogenesis, diagnosis and treatment
13. Impaired iron uptake and transferrin binding by erythroblasts in the anaemia of rheumatoid arthritis
14. The biology of transferrin
15. Microheterogeneity of human transferrin, a biological phenomenon studied by isoelectric focusing in immobilized pH gradients
16. Human serum sialo transferrins in diseases
17. Functional properties of the carbohydrate moiety of human transferrin
18. Carbohydrate-structure-dependent recognition of desialylated serum glycoproteins in the liver and leukocytes
19. Variations in the relative proportions of microheterogeneous forms of plasma glycoproteins in pregnancy and disease
20. Microheterogeneity of alpha-1-acid glycoprotein in the detection of intercurrent infection in systemic lupus erythematosus
21. Changes in the serum level and affinity for concanavalin a of human alpha-1-proteinase inhibitor in severe burn patients: relationship to natural killer cell activity
22. Microheterogeneity forms of alpha-1-acid glycoprotein as indicators of rheumatoid arthritis activity
23. Abnormally-fucosylated serum haptoglobins in patients with inflammatory joint disease
24. Transforming growth factor β1 influences glycosylation of α1-protease inhibitor in human hepatoma cell lines
25. Interleukin 6, the third mediator of acutephase reaction, modulates hepatic protein synthesis in human and mouse. Comparison with interleukin 1 β and tumor necrosis factor α
26. Cachetin/tumor necrosis factor regulates hepatic acute-phase gene expression
27. Effects of monocytic products, recombinant interleukin-1 and recombinant interleukin-6 on glycosylation of alpha-1-acid glycoprotein: studies with primary human hepatocyte cultures and rats
28. The phenomenon of the acute phase response
29. The American Rheumatism Association 1987. Revised criteria for the classification of rheumatoid arthritis
30. 125I C1q binding test for soluble immune complexes
31. Quantitation of subfractions of serum transferrins using crossed immunofocusing with Immobiline gels
32. Glycosylation at specific sites of erythropoietin is essential for biosynthesis, secretion and biological function
33. Evidence for the involvement of the transcortin carbohydrate moiety in the glycoprotein interaction with plasma membrane of human placenta syncytiotrophoblast
34. Con A-nonreactive human alpha 1-acid glycoprotein (AGP) is more effective in modulation of lymphocyte proliferation than Con A-reactive AGP serum variants
35. Similarities between the transferrin receptor proteins on human reticulocytes and human placentae
36. Inhibition by interleukin-1 of the action of erythropoietin on erythroid precursors and its possible role in the pathogenesis of hypoplastic anaemias
37. Effects of recombinant tumor necrosis factor alpha, recombinant human gamma-interferon, and prostaglandin E on colony formation of human hematopoietic progenitor cells stimulated by natural human pluripotent colony stimulating factor, pluripoietin alpha, and recombinant erythropoietin in serum-free cultures
38. The interleukins in acquired disease
39. Detection of tumor necrosis factor alpha but not tumor necrosis factor beta in rheumatoid arthritis synovial fluid and serum
40. Transferrin receptor number, synthesis and endocytosis during erythropoietin-induced maturation of Friend virus-infected erythroid cells
41. Production of soluble transferrin receptor by K562 erythroleukemia cells
42. Circulating transferrin receptor in human serum
43. Serum transferrin receptor: A quantitative measure of tissue iron deficiency
44. Interferon β2/B-cell stimulating factor 2/interleukin 6 affects glycosylation of acute phase proteins in human hepatoma cell lines
45. Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes
46. Interleukin-6 (IL-6) in synovial fluid and serum of patients with rheumatic diseases