Comparative in vitro myelotoxicity of FCE 24517, a distamycin derivative, to human, canine and murine hematopoietic progenitor cells

Investigational New Drugs

Volumn 10, Issue 4, 1992, Pages 255-261

  Volpe, Donna A ^a,b   Du, De Lin ^a,c   Zurlo, Maria Grazia ^d   Mongelli, Nicola ^d   Murphy, Martin J ^a  

^a Cancer Prevention Institute Dayton   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^d PFIZER INC   (United States)

Author keywords

canine; FCE 24517; human; in vitro; murine; myelotoxicity

Indexed keywords

TALLIMUSTINE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW TOXICITY; BURST FORMING UNIT E; COLONY FORMATION; COLONY FORMING UNIT E; COLONY FORMING UNIT GM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MEGAKARYOCYTE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; BONE MARROW DISEASES; COLONY-FORMING UNITS ASSAY; COMPARATIVE STUDY; DISTAMYCINS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEMATOPOIETIC STEM CELLS; HUMAN; IN VITRO; MICE; NITROGEN MUSTARD COMPOUNDS;

EID: 0027074072     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/BF00944178     Document Type: Article

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