-
2
-
-
0026554009
-
Glycosylation of Nuclear and Cytoplasmic Proteins is Ubiquitous and Dynamic
-
of outstanding interest, A succinct review of the most recent data on O-GlcNAc. Contains the most complete list of O-GlcNAc-bearing proteins, sites of attachment and speculations about possible functions.
-
(1992)
Biocbem Soc Trans
, vol.20
, pp. 264-269
-
-
Halttwanger1
Kelly2
Roquemore3
Blomberg4
Dong5
Kreppel6
Chou7
Hart8
-
4
-
-
0026571343
-
Mucin-type Glycoproteins
-
of special interest, The most current and excellent detailed review on mucins. Covers recent views of genomic organization, protein and carbohydate structures, multimeric complexes, biosynthesis and intracellular transport, functions and pathology.
-
(1992)
CRC Crit Rev Biocbem Mol Biol
, vol.27
, pp. 57-92
-
-
Strous1
Dekker2
-
7
-
-
0026516422
-
Glycosylation Engineering
-
of special interest, A thoughtful and well written evaluation of methods for the generation of specific glycoforms of glycoproteins: production in different cell types; site-directed mutagenesis; the use of glycosylation inhibitors; or by exogenous treatments with enzymes. Particularly relevant to pharmaceutical interests in recombinant glycoproteins.
-
(1992)
Glycobiol
, vol.2
, pp. 99-107
-
-
Stanley1
-
10
-
-
0026848764
-
Glycoprotein Pharmaceuticals: Scientific and Regulatory Considerations, and the US Orphan Drug Act
-
of special interest, Essential reading for glycobiologists in the pharmaceutical industry. Presents a well developed discussion of the roles of glycosylation in pharmokinetics and immunogenicity of glycoprotein pharmaceuticals. Also, contains a thorough discussion of regulatory issues and documents related to glycoprotein therapeutics.
-
(1992)
Trends Biotecbnol
, vol.10
, pp. 114-120
-
-
Liu1
-
11
-
-
0026507880
-
Proteoglycans: Many Forms and Many Functions
-
of special interest, Outstanding presentation of the diversity in structure and functions of proteoglycans. Excellent article for bringing the non-specialist up to date on recent developments.
-
(1992)
FASEB J
, vol.6
, pp. 861-870
-
-
Hardingham1
Fosang2
-
12
-
-
0026744148
-
Cell Surface Heparan Sulfate Proteoglycans
-
of special interest, A more focused review of particular interest to biologists studying cell surfaces and growth factors. Provides a succinct picture of heparan sulfate proteoglycan synthesis, catabolism and functions.
-
(1992)
J Biol Chem
, vol.267
, pp. 9451-9454
-
-
Yanagishita1
Hascall2
-
15
-
-
0026856908
-
Glycosyl-phosphatidylinositol Membrane Anchors: The Tale of a Tail
-
of special interest, Presents a concise historical perspective on structures and functions of GPIs. Particularly strong in the presentation of current views of GPI functions.
-
(1992)
Biochem Soc Trans
, vol.20
, pp. 243-256
-
-
Ferguson1
-
17
-
-
0026013817
-
Phosphatidylinositol membrane anchors and T-cell activation
-
(1991)
Immunology Today
, vol.12
, pp. 36-41
-
-
Robinson1
-
18
-
-
0026786445
-
Localization of O-GlcNAc Modification on the Serum Response Transcription Factor (SRF)
-
of outstanding interest, Excellent examples of fast atom bombardment mass spectrometric and sequencing methods for localizing O-GIcNAc glycosylation. The most heavily glycosylated site on SRF was localized in the region of glycoprotein required for transcription initiation.
-
(1992)
J Biol Chem
, vol.267
, pp. 16911-16921
-
-
Reason1
Morris2
Panico3
Marais4
Treisman5
Halttwanger6
Hart7
Kelly8
Dell9
-
19
-
-
0026736507
-
A Structural Polypeptide of the Baculovirus Autograpba californica Nuclear Polyhedrosis Virus Contains O-Linked N-Acetylglucosamine
-
(1992)
J Virol
, vol.66
, pp. 3324-3329
-
-
Whitford1
Faulkner2
-
20
-
-
0025810911
-
Rotavirus Ns26 Is Modified by Addition of Single O-Linked Residues of N-Acetylglucosamine
-
(1992)
Virology
, vol.182
, pp. 8-16
-
-
Gonzalez1
Burrone2
-
21
-
-
0026541971
-
Vertebrate Lens α-Crystallins are Modified by O-Linked N-Acetylglucosamine
-
of special interest, Demonstrates that the α-crystallins of the eye lens, which are heat-shock proteins in non-lens tissues, are glycosylated by O-GIcNAc. Mass spectrometry and gas-phase sequencing techniques localize attachment sites and confirm the lack of modification of the monosaccharide moieties.
-
(1992)
J Biol Chem
, vol.267
, pp. 555-563
-
-
Roquemore1
Dell2
Morris3
Panico4
Reason5
Savoy6
Wistow7
Zigler8
Earles9
Hart10
-
22
-
-
0026662974
-
Characterization and Dynamics of O-Linked Glycosylation of Human Cytokeratin 8 and 18
-
of outstanding interest, Pulse-chase analyses demonstrate that O-GicNAc on cytokeratins is more highly dynamic than the polypeptide backbone. Supports the hypothesis that O-GicNAc has the hallmarks of a regulatory modification.
-
(1992)
J Biol Chem
, vol.267
, pp. 3901-3906
-
-
Chou1
Smith2
Omary3
-
23
-
-
0026690924
-
The Cytoskeletal Protein Talin Is O-Glycosylated
-
of special interest, In addition to describing another important Ctoskeletal protein that is glycosylated and localizing the glycosylation-sites, this paper also suggests a possible role for O-GlcNAc in the interaction of talin with vinculin to form the focal contacts attaching actin to the plasma membrane.
-
(1992)
J Biol Chem
, vol.276
, pp. 14424-14428
-
-
Hagmann1
Grob2
Burger3
-
24
-
-
0026030545
-
Lymphocyte Activation Induces Rapid Changes in Nuclear and Cytoplasmic Glycoproteins
-
of special interest, Provides further support for the notion that O-GlcNAc is possibly a regulatory modification by demonstrating rapid changes in O-GlcNAc levels on activated lymphocytes. Similar to early work on phosphorylation in this system.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 1701-1705
-
-
Kearse1
Hart2
-
25
-
-
0026795976
-
Glycosylation of Nuclear and Cytoplasmic Proteins. Purification and Characterization of a Uridine Diphospho-N-Acetyl glucosamine:Polypeptide B-N-Acetylglucosaminyltransferase
-
of special interest, Describes the key enzyme that attaches O-GlcNAc to proteins. This glycosyltransferase is completely different from previously described Golgi glycosyltransferases in nearly all of its properties.
-
(1992)
J Biol Chem
, vol.267
, pp. 9005-9013
-
-
Halttwanger1
Blomberg2
Hart3
-
27
-
-
0025995274
-
Glycogen Structure and Biogenesis
-
of special interest, A detailed review of all aspects of glycogen biochemistry. Particularly relevant discussion about glycogen biosynthesis and about the glycogen protein primer.
-
(1991)
Int J Biochem
, vol.23
, pp. 1335-1352
-
-
Calder1
-
33
-
-
0026700166
-
0-linked Fucose Is Present in the First Epidermal Growth Factor Domain of factor XII But Not Protein C
-
(1992)
J Biol Chem
, vol.267
, pp. 5102-5107
-
-
Harris1
Ling2
Spellaian3
-
36
-
-
0026765426
-
Purification and Characterization of a UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase Specific for Glycosylation of Threonine Residues
-
of special interest, Excellent characterization of a key enzyme in mucin biosynthesis. Data suggest that the enzyme will glycosylate any exposed threonine residue, but surprisingly has no activity against senne containing peptides.
-
(1992)
J Biol Chem
, vol.267
, pp. 12709-12716
-
-
Wang1
Abernethy2
Eckhardt3
Hill4
-
37
-
-
0025980339
-
Cell surface mucin-type glycoproteins and mucin-like domains
-
of special interest, Excellent short review of the structure and functions of mucin domains present on many important membrane proteins.
-
(1991)
Glycobiol
, vol.1
, pp. 131-138
-
-
Carraway1
Hull2
-
38
-
-
0026750998
-
Epiglycanin — A Carcinoma-specific Mucin-type Glycoprotein of the Mouse TA3 Tumour
-
of special interest, Describes the history and current knowledge of membrane bound mucin-type glycoproteins of carcinomas. One of the best examples of importance to cancer of the “masking” of normal cell surface receptors by abnomial expression of a glycoprotein.
-
(1992)
Glycobiol
, vol.2
, pp. 173-180
-
-
Codington1
Haavik2
-
39
-
-
0026049185
-
The “Yellow Brick Road” to Branched Complex N-Glycans
-
of special interest, A succinct summary of the development and current status of knowledge about the key N-Acetylglucosaminyltransferases that are involved in the extensive branching of N-linked oligosaccharides.
-
(1991)
Glycobiol
, vol.1
, pp. 153-161
-
-
Schachter1
-
44
-
-
0026716017
-
Oligosaccharyltransferase Activity Is Associated with a Protein Complex Composed of Ribophorins I and II and a 48 kD Protein
-
of outstanding interest, Provides convincing data that the key enzyme in N-linked glycan synthesis comprises three subunits, including the two ribophorins. Ribophorin 1 appears to be the dolichol-binding subunit. Represents a major breakthrough in solving a long-term intractable problem.
-
(1992)
Cell
, vol.69
, pp. 55-65
-
-
Kelleher1
Kreibich2
Gilmore3
-
45
-
-
0026607905
-
The Yeast wbp1 Is Essential for Oligosaccharyl Transferase Activity in Vivo and in Vitro
-
of special interest, Identifies an essential gene in yeast that is either the oligosaccharyltransferase or required for its activity. Identification of this gene will prove invaluable towards understanding the molecular features of this key enzyme.
-
(1992)
EMBO J
, vol.11
, pp. 2071-2075
-
-
Te Heesen1
Janetzky2
Lehle3
Aebi4
-
46
-
-
0021956734
-
Oligosaccharide Microheterogeneity of the Murine Major Histocompatibility Antigens. Reproducible Site-specific Patterns of Sialylation and Branching in Asparagine-linked Oligosaccharides
-
(1985)
J Biol Chem
, vol.260
, pp. 4046-4054
-
-
Swiedler1
Freed2
Tarentino3
Plummer4
Hart5
-
47
-
-
0022898398
-
Influence of Quaternary Structure On Glycosylation: Differential Subunit Association Affects the Site-specific Glycosylation of the Common β-Chain From 1a and LFA-1
-
(1986)
J Biol Chem
, vol.261
, pp. 13186-13196
-
-
Dahms1
Hart2
-
49
-
-
0026342559
-
Clearing Up Glycoprotein Hormones
-
of special interest, Excellent short review on glycoprotein clearance systems particularly relevant to glycoprotein hormones.
-
(1991)
Cell
, vol.67
, pp. 1029-1032
-
-
Drickamer1
-
51
-
-
0026095033
-
Diversification of the IgG Molecule by Oligosaccharides
-
of special interest, Presents a detailed structural view of the glycoforms of IgG. Describes current concepts with respect to the roles of IgG glycoforms in disease, aging and pregnancy, presenting some plausable models for the involvement of oligosaccharides in the self-association of IgG rheumatoid factors.
-
(1991)
Mol Immunol
, vol.28
, pp. 1369-1378
-
-
Rudd1
Leatherbarrow2
Rademacher3
Dwek4
-
53
-
-
0026317511
-
Glycosidase Inhibitors: Inhibitors of N-Linked Ohgosaccharide Processing
-
(1991)
FASEB J
, vol.5
, pp. 3055-3063
-
-
Elbein1
-
55
-
-
0026668826
-
Loss of One Asparagine-linked Oligosaccharide From Human Transferrin Receptors Results in Specific Cleavage and Association with the Endoplasmic Reticulum
-
(1992)
J Biol Chem
, vol.267
, pp. 4916-4923
-
-
Hoe1
Hunt2
-
57
-
-
0026533141
-
Role of Asparagine-linked Glycosylation in Human Immunodeficiency Virus Type 1 Transmembrane Envelope Function
-
(1992)
Virology
, vol.187
, pp. 377-382
-
-
Dedera1
Gu2
Ratner3
-
58
-
-
0026583798
-
Folding of intestinal brush border enzymes. Evidence that high-mannose glycosylation is an essential early event
-
(1992)
Biochemistry
, vol.31
, pp. 2266-2272
-
-
Danielsen1
-
59
-
-
0025789665
-
Lysosomal Membrane Glycoproteins. Structure, Biosynthesis, and Intracellular Trafficking
-
of special interest, Definitive review describing the structure, biosynthesis and functions of the heavily glycosylated membrane glycoproteins that appear to not only protect the lysosome from autolysis, but also function in adhesion at the cell surface.
-
(1991)
J Biol Chem
, vol.266
, pp. 21327-21330
-
-
Fukuda1
-
60
-
-
0025981417
-
Glycosylation of Recombinant Protein Therapeutics: Control and Functional Implications
-
(1991)
Glycobiol
, vol.1
, pp. 115-130
-
-
Cumming1
-
61
-
-
0025918707
-
Structures and Functional Roles of the Sugar Chains of Human Erythropoietins
-
(1991)
Glycobiol
, vol.1
, pp. 337-346
-
-
Takeuchi1
Kobata2
-
62
-
-
0025945169
-
Oligosaccharides at Each Glycosylation Site Make Structure-dependent Contributions to Biological Properties of Human Tissue Plasminogen Activator
-
of special interest, One of the best examples of glycosylation modulating the kinetic properties of an enzyme. Represents one of a select few proteins in which glycosylation has been examined at the single site level.
-
(1991)
Glycobiol
, vol.1
, pp. 411-417
-
-
Howard1
Wittwer2
Welply3
-
63
-
-
0026702568
-
Role of Sugar Chains in the Expression of the Biological Activity of Human Erythropoietin
-
of special interest, The most recent in a series of papers from several laboratories that examine the role(s) of oligosaccharides on erythropoietin. Supports the role of erythropoietin's N-linked glycosylation in vivo.
-
(1992)
J Biol Chem
, vol.267
, pp. 7703-7709
-
-
Higuchi1
Oh-eda2
Kuboniwa3
Tomonoh4
Shimonaka5
Ochi6
-
65
-
-
0026582182
-
Changes in Normal Glycosylation Mechanisms in Autoimmune Rheumatic Disease
-
of special interest, Presents recent clinically relevant data with regard to interrelationship between lymphocytic galatosyltransferase and undergalactosylated IgG in normal and disease conditions.
-
(1992)
J Clin Invest
, vol.89
, pp. 1021-1031
-
-
Axford1
Sumar2
Alavi3
Isenberg4
Young5
Bodman6
Roitt7
-
67
-
-
0026342111
-
Leukocyte-Endothelial Cell Recognition: Three (Or More) Steps to Specificity and Diversity
-
of special interest, Presents a cohesive picture of mechanisms and molecules involved in targeting leukocytes to sites of inflammation. Presents one of the clearest and most cohesive views on the large amount of data on selectins.
-
(1991)
Cell
, vol.67
, pp. 1033-1036
-
-
Butcher1
-
68
-
-
0026842845
-
Selectins and Other Mammalian Sialic Acid-binding Lectins
-
of special interest, A general discussion of sialic acid-binding lectins important in mammalian cells. Presents a general overview by placing the selectins in context of other sialic acid binding proteins.
-
(1992)
Curr Opin Cell Biol
, vol.4
, pp. 257-266
-
-
Varki1
-
69
-
-
14744273042
-
Carbohydrate-based Therapeutics
-
of special interest, Summarizes current work underway in pharmaceutical companies to develop carbohydrate-based drugs. A good description of the major growth areas.
-
(1991)
Biotechnology
, vol.9
, pp. 609-613
-
-
Hodgson1
-
70
-
-
0026326839
-
Will Complex Carbohydrate Ligands of Vascular Selectins Be the Next Generation of Non-steroidal Antiinflammatory Drugs?
-
(1991)
Glycoconjugate J
, vol.8
, pp. 381-386
-
-
Winkelhake1
-
71
-
-
77957183382
-
Diversity in the Sialic Acids
-
of special interest, Excellent synopsis of the current structural diversity and nomenclature of sialic acids. A must for people trying to understand oligosaccharide structural diversity.
-
(1992)
Glycobiology
, vol.2
, pp. 25-40
-
-
Varki1
-
72
-
-
0026069647
-
Biosynthesis and Function of N- and O-Substituted Sialic Acids
-
of special interest, Lucid description of the biosynthesis of the different types of sialic acids. Provides an excellent historical perspective.
-
(1991)
Glycobiology
, vol.1
, pp. 449-452
-
-
Schauer1
-
73
-
-
0026567823
-
Polysialylation: From Bacteria to Brains
-
of special interest, The definitive review on polysialic acid. Focuses on recent developments in occurance, structure, function and biosynthesis.
-
(1992)
Glycobiology
, vol.2
, pp. 5-23
-
-
Troy1
-
74
-
-
0025769326
-
A Novel Cell Surface Trans-sialidase of Trypanosoma cruzi Generates a Stage-specific Epitope Required for Invasion of Mammalian Cells
-
of outstanding interest, Describes the initial characterization of a novel trans-sialidase enzyme that transfers sialic acid residues from host glycoconjugates to the surface of trypanosomes emerging from infected macrophages. These sialic acids are essential for parasite adhesion to host macrophages.
-
(1991)
Cell
, vol.65
, pp. 1117-1125
-
-
Schenkman1
Jiang2
Hart3
Nussenzweig4
|