Oncostatin M

Progress in Growth Factor Research

Volumn 4, Issue 2, 1992, Pages 157-170

  Bruce, A Gregory ^a   Linsley, Peter S ^a   Rose, Timothy M ^b  

^a BRISTOL MYERS SQUIBB   (United States)

^b FRED HUTCHINSON CANCER RESEARCH CENTER   (United States)

Author keywords

ciliary neurotrophic factor; granulocyte colony stimulating factor; growth hormone; hematopoietins; interleukin 11; interleukin 6; Leukemia inhibitory factor; receptors

Indexed keywords

CELL SURFACE RECEPTOR; CYTOKINE; DNA; ONCOSTATIN M; ONCOSTATIN M RECEPTOR; PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; DRUG EFFECT; GENETICS; HUMAN; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; CYTOKINES; DNA; HUMAN; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PEPTIDES; RECEPTORS, CELL SURFACE; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 0027027118     PISSN: 09552235     EISSN: None     Source Type: Journal    
DOI: 10.1016/0955-2235(92)90029-H     Document Type: Article

References (69)

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8. Amplification and expression of heterologous oncostatin M in chinese hamster ovary cells
9. Cleavage of a hydrophilic C-terminal domain increases growth-inhibitory activity of oncostatin M
10. Coiled-coils in alpha helix-containing proteins: analysis of the residue types within the heptad repeat and the use of these data in the prediction of coiled-coils in other proteins
11. Disulfide bond assignment and identification of regions required for functional activity on oncostatin M
12. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates mRNA degradation
13. Purification and characterization of cytostatic lymphokines produced by activated human T lymphokines
14. Oncostatin M as a potent mitogen for AIDS-Kaposi's sarcoma-derived cells
15. Regulation of cell growth by recombinant oncostatin M
16. Oncostatin M is a differentiation factor for myeloid leukemia cells
17. Clonal suppression of HL60 and U937 cells by recombinant human leukemia inhibitory factor in combination with GM-CSF
18. Enhanced suppression of human myeloid leukemic cell lines by combinations of IL-6, LIF, GM-CSF and G-CSF
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29. Monokine-induced gene expression of a human endothelial cell-derived neutrophil chemotactic factor
30. Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 production in endothelial cells
31. Recombinant oncostatin M stimulates the production of acute phase proteins in HepG2 cells and rat primary hepatocytes in vitro
32. Interferon-beta2/B-cell stimulatory factor type 2 shares identity with monocyte hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells
33. Interleukin-6 and the acute phase protein
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35. Human hepatocyte-stimulating factor-III and interleukin-6 are structurally and immunologically distinct but regulate the production of the same acute phase plasma proteins
36. Macrophage-derived factors increase low density lipoprotein uptake and receptor number in cultured human liver cells
37. Oncostatin M up-regulates low density lipoprotein receptors in HepG2 Cells by a novel mechanism
38. Importance of growth hormone for the induction of hepatic low density lipoprotein receptors
39. Oncostatin M stimulates urokinase-type plasminogen activator activity in human synovial fibroblasts
40. Oncostatin M: a novel regulator of endothelial cell properties
41. Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells
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43. The chromosomal gene structure and two mRNAs for human granulocyte colony-stimulating factor
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53. Human differentiation-stimulating factor (leukemia inhibitory factor, human interleukin DA) gene maps distal to the Ewing sarcoma breakpoint on 22q
54. Identification and characterization of cellular receptors for the growth regulator, oncostatin M
55. Interleukin-6 signal transducer gp130 mediates oncostatin M signaling
56. The IL-6 signal transducer, gp130: an oncostatin M receptor and affinity converter for the LIF receptor
57. CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130
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64. Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
65. Oncostatin M binds the high-affinity leukemia inhibitory factor receptor
66. Regulation of EGR-1, c-jun, and c-myc gene expression by oncostatin M
67. Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation
68. Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family
69. yes tyrosine kinase