Quantitative variability and multilocus polymorphism under epistatic selection

Theoretical Population Biology

Volumn 42, Issue 3, 1992, Pages 254-283

  Zhivotovsky, Lev A ^a   Gavrilets, Sergey ^a  

^a VAVILOV INSTITUTE OF GENERAL GENETICS   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

EPISTATIC SELECTION; FITNESS; MULTILOCUS POLYMORPHISM;

ALLELE; ANIMAL; ARTICLE; BIOLOGICAL MODEL; CHROMOSOME MAP; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC EPISTASIS; GENETIC POLYMORPHISM; GENETIC SELECTION; GENETIC VARIABILITY; GENETICS; HUMAN; MULTIGENE FAMILY;

ALLELES; ANIMAL; CHROMOSOME MAPPING; EPISTASIS, GENETIC; GENE FREQUENCY; HUMAN; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC; MULTIGENE FAMILY; POLYMORPHISM (GENETICS); SELECTION (GENETICS); SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; VARIATION (GENETICS);

EID: 0027008226     PISSN: 00405809     EISSN: 10960325     Source Type: Journal    
DOI: 10.1016/0040-5809(92)90015-L     Document Type: Article

References (56)

1. The maintenance of polygenic variation through a balance between mutation and stabilizing selection
2. The effect of linkage and density-dependent regulation on gene flow
3. Pleiotropic models of quantitative models of quantitative variation
4. Evolutionary quantitative genetics: how little do we know?
5. Natural and sexual selection on many loci
6. The effects of selection on genetic variability
7. The genetic variability of polygenic characters under optimizing selection, mutation and drift
8. The maintenance of the genetic variability of polygenic characters by heterozygous advantage
9. Linkage disequilibrium and genetic variability
10. The effect of selection on genetic variability: a simulation study
11. Constraints for the evolution of functionally coupled characters a nonlinear analysis of a phenotypic model
12. Mutation-selection balance and continuum of alleles models
13. Epistasis in the multiple locus symmetric viability model
14. Properties of equilibria in multilocus genetic system
15. Selection in complex genetic systems. I. The symmetric equilibria of the three-locus symmetric viability model
16. Equilibrium distributions of continuous polygenic traits
17. Covariances between arbitrary relatives with linkage disequilibrium
18. Influence of stabilizing selection on the genotypic variance and linkage disequilibrium
19. Pleiotropic overdominance and the maintenance of genetic variation in polygenic characters
20. Genotype-environment interactions and the maintenance of polygenic variation
21. Additive variation maintained under stabilizing selection: a two-locus model of pleiotropy for two quantitative characters
22. Genotypic variation for a quantitative character maintained under stabilizing selection: epistasis
23. Unexpected behavior in two locus genetic models: an analysis of marginal overdominance
24. Multilocus population genetics with weak epistasis. II. Equilibrium properties of multilocus selection: what is the unit of selection?
25. Multiple equilibria and maintenance of additive genetic variance in a model of pleiotropy
26. General two-locus selection models: Some objectives, results and interpretations
27. Principles of polymorphism and epistasis for multilocus systems
28. Linkage and selection: two-locus symmetric viability model
29. Variation maintained in quantitative traits with mutation-selection balance pleiotropic side-effect on fitness trait
30. A stochastic model concerning the maintenance of genetic variability in quantitative characters
31. Stable equilibria for the optimum model
32. The maintenance of genetic variability by mutation in a polygenic character with linked loci
33. The genetic covariance between characters maintained by pleiotropic mutations
34. The interaction of selection and linkage. II. Optimum models
35. The evolution of one- and two-locus systems
36. The maintenance of genetic variability in two-locus models of stabilizing selection
37. The effect of selection against extreme deviants based on deviation or on homozygosis
38. On treating the chromosome as the unit of selection
39. Variance components of fitness under stabilizing selection
40. Cis-trans effects induced by linkage disequilibrium
41. Heritable genetic variation via mutation-selection balance: Lersh's zeta meets the abdominal bristle
42. Population genetic models for polygenic variation and evolution
43. Dynamics of polygenic characters under selection
44. Coevolution of functionally constrained characters: prerequisites for adaptive versatility
45. The influence of variation and of developmental constraints on the rate of multivariate phenotypic evolution
46. Inconsistencies in standard approximations for selection coefficients at loci affecting a polygenic character
47. The effect of linkage and linkage disequilibrium on the covariances of noninbred relatives
48. Evolution in populations in approximate equilibrium
49. Stabilizing selection and linkage disequilibrium
50. Selection models in quantitative genetics