A major barley allergen associated with baker's asthma disease is a glycosylated monomeric inhibitor of insect α-amylase: cDNA cloning and chromosomal location of the gene

Plant Molecular Biology

Volumn 20, Issue 3, 1992, Pages 451-458

  Mena, Montaña ^a   Sanchez Monge, Rosa ^b   Gomez, Luis ^b   Salcedo, Gabriel ^b   Carbonero, Pilar ^a,b  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b Electrotechnical Section   (Spain)

Author keywords

amylase monomeric inhibitor; baker's asthma; barley; cDNA cloning; genetic mapping; glycosylated allergen

Indexed keywords

ALLERGEN; AMYLASE; GLYCOPROTEIN; IAM1 PROTEIN, HORDEUM VULGARE; VEGETABLE PROTEIN;

AIR POLLUTANT; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; ASTHMA; CHEMISTRY; CHROMOSOME MAP; COMPARATIVE STUDY; DRUG EFFECT; ENZYMOLOGY; FLOUR; GENETICS; HORDEUM; IATROGENIC DISEASE; INSECT; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OCCUPATIONAL DISEASE; PLANT SEED; SEQUENCE HOMOLOGY;

AIR POLLUTANTS, OCCUPATIONAL; ALLERGENS; ALPHA-AMYLASE; AMINO ACID SEQUENCE; ANIMAL; ASTHMA; BASE SEQUENCE; CHROMOSOME MAPPING; COMPARATIVE STUDY; FLOUR; GLYCOPROTEINS; HORDEUM; INSECTS; MOLECULAR SEQUENCE DATA; OCCUPATIONAL DISEASES; PLANT PROTEINS; SEEDS; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, NON-U.S. GOV'T;

EID: 0026954625     PISSN: 01674412     EISSN: 15735028     Source Type: Journal    
DOI: 10.1007/BF00040604     Document Type: Article

References (33)

1. Hypersensitivity to inhaled flour allergens. Comparison between cereals
2. IgE antibodies to wheat flour components. Studies with sera from patients with baker's asthma and coeliac conditions
3. Allergies to cereals
4. A barley flour inhibitor of insect α-amylase is a major allergen associated with baker's asthma disease
5. Flour allergy in bakers
6. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
7. Plant proteinaceous inhibitors of proteinases and α-amylases
8. Alpha-amylase/trypsin inhibitors and thionins. Possible defence proteins from barley
9. Site-directed mutagenesis and expression in Escherichia coli of WMAI-1, a wheat monomeric inhibitor of insect α-amylase
10. Extreme variations in the ratios of non-synonymous to synonymous nucleotide substitution rates in signal peptide evolution
11. Cloning of cDNA and chromosomal location of genes encoding the three types of subunits of the wheat tetrameric inhibitor of insect α-amylase
12. Blot analyses of glycoconjugates: enzyme-hydrazide, a novel reagent for the detection of aldehydes
13. Members of the α-amylase inhibitors family from wheat endosperm are major allergens associated with baker's asthma
14. Wheat tetrameric inhibitors of insect α-amylase: alloploid heterosis at the molecular level
15. Baker's asthma, immediate and late reactions
16. Prediction of protein antigenic determinants from amino acid sequences
17. The antigenic index: a novel algorithm for predicting antigenic determinants
18. The complete amino acid sequence of a major wheat protein inhibitor of α-amylase
19. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
20. A dimeric inhibitor of insect α-amylase from barley. Cloning of the cDNA and identification of the protein
21. Electrophoretic resolution of the major outer membrane of Escherichia coli K12 into four bands
22. Rapid isolation of high molecular weight plant DNA
23. Western blot analysis of water-soluble wheat flour (Triticum vulgaris) allergens
24. Occupational and non-occupational respiratory allergy in bakers
25. The gene for trypsin inhibitor CMe is regulated in trans by the lys 3a locus in the endosperm of barley (Hordeum vulgare L)
26. Wheat and barley allergens associated with baker's asthma: glycosylated subunits of the α-amylase inhibitors family have enhanced IgE-binding capacity
27. A tetrameric inhibitor of insect α-amylase from barley
28. DNA sequencing with chain terminating inhibitors
29. Chromosomal location of the structural genes for the Mr 75000 τ-secalins in Secale montanum Guss: evidence for a translocation involving chromosomes 2R and 6R in cultivated rye (Secale cereale L.)
30. A method for the detection of IgE binding sequences of allergens based on a modification of epitope mapping
31. Isolation of cDNA clones for the human complement protein factor B, a class III major histocompatibility complex gene product
32. Rapid bacteriophage sedimentation in the presence of polyethylene glycol and its application to large scale virus purification