-
1
-
-
0026770377
-
Integrins: Versatility, Modulation, and Signaling in Cell Adhesion
-
of special interest, A comprehensive review of the integrins, which emphasizes their dynamic roles in adhesion and signaling.
-
(1992)
Cell
, vol.69
, pp. 11-25
-
-
Hynes1
-
2
-
-
0026503656
-
Contact and Adhesive Specificities in the Associations, Migrations, and Targeting of Cells and Axons
-
of special interest, Broad but useful overview of major families of adhesion molecules as well as a more detailed analysis of their roles in neuronal adhesion.
-
(1992)
Cell
, vol.68
, pp. 303-322
-
-
Hynes1
Lander2
-
3
-
-
0025950158
-
A Dual Receptor System Is Required for Basic Fibroblast Growth Factor Activity
-
(1991)
Cell
, vol.67
, pp. 229-231
-
-
Klagsbrun1
Baird2
-
4
-
-
0025931230
-
The Int-2/Fgf-3 Oncogene Product Is Secreted and Associates with Extracellular Matrix:Implications for Cell Transformation
-
(1991)
Mol Cell Biol
, vol.11
, pp. 5929-5936
-
-
Kiefer1
Peters2
Dickson3
-
8
-
-
0026343904
-
Regulation of Integrin-type Cell Adhesion Receptors by Cytokines
-
(1991)
J Biol Chem
, vol.266
, pp. 23505-23509
-
-
Santala1
Heino2
-
10
-
-
0025928809
-
GTP-Binding Proteins and Platelet Activation
-
of special interest, Detailed consideration of G proteins, adhesion proteins and other aspects of signal transduction in platelets.
-
(1991)
Progr Hemost Thromb
, vol.10
, pp. 127-174
-
-
Brass1
Manning2
Shattil3
-
11
-
-
0025781203
-
Coordinate Interactions of Protein Tyrosine Kinases and Protein Tyrosine Phosphatases in T-cell Receptor-mediated Signalling
-
of special interest, Reviews the evidence that illustrates cooperative signaling between the T-cell receptor complex and CD4. This paradigm should be relevant in efforts to determine mechanisms of cooperative signaling among adhesion receptors and their partners.
-
(1991)
Curr Opin Cell Biol
, vol.3
, pp. 862-868
-
-
Shaw1
Thomas2
-
12
-
-
0025730216
-
Lymphocyte Interactions with Extracellular Matrix
-
(1991)
FASEB J
, vol.5
, pp. 2292-2299
-
-
Shimizu1
Shaw2
-
13
-
-
0025823018
-
Genetic Analysis of Proteoglycan Structure, Function and Metabolism
-
(1991)
Curr Opin Cell Biol
, vol.3
, pp. 805-816
-
-
Esko1
-
14
-
-
0026685854
-
Biology of the Syndecans: A Family of Transmembrane Heparan Sulfate Proteoglycans
-
of special interest, This is a timely review, as it has recently become clear that the original syndecan studied by these investigators for many years is part of a family of transmembrane proteoglycans. The roles of these and other cell surface heparan sulfate proteoglycans are reviewed from a developmental and signaling perspective.
-
(1992)
Annual Review of Cell Biology
, vol.8
, pp. 1-43
-
-
Bernfield1
Kokenyesi2
Kato3
Hinkes4
Spring5
Gallo6
Lose7
-
15
-
-
0025734184
-
Adhesive Recognition Sequences
-
(1991)
J Biol Chem
, vol.266
, pp. 12809-12812
-
-
Yamada1
-
16
-
-
0026020583
-
Receptor Functions for the Integrin VLA-3: Fibronectin, Collagen, and Laminin Binding Are Differentially Influenced by Arg-Gly-Asp Peptide and by Divalent Cations
-
of special interest, Provides insight into some of the parameters regulating ligand preference bt promiscuous integrins.
-
(1991)
J Cell Biol
, vol.112
, pp. 169-181
-
-
Elices1
Urry2
Hemler3
-
17
-
-
0026084784
-
Cell-Surface Regulation of β1 Integrin Activity on Developing Retinal Neurons
-
of special interest, Use of an adhesion-promoting anti-β1 antibody to show that a developmentally programmed down-regulation of integrin-laminin interactions was due to altered α6β1 laminin receptor avidity, not loss of receptor expression.
-
(1991)
Nature
, vol.350
, pp. 68-71
-
-
Neugebauer1
Reichardt2
-
18
-
-
0026566854
-
Cloning and Characterization of a Gene That Regulates Cell Adhesion
-
of outstanding interest, Identification, by a clever bioassay and expression cloning, of a novel gene coding for a 142 amino acid cytoplasmic protein, CAR, that can regulate the affinity of integrin complexes. Documents the existence of yet another level of complexity in the regulation of integrin function. Could indicate the existence of integrin-associated subunits analogous to those associated with the T-cell receptor.
-
(1992)
Nature
, vol.356
, pp. 529-532
-
-
Pullman1
Bodmer2
-
19
-
-
0026603414
-
Protein Kinase C Involvement in Focal Adhesion Formation
-
of special interest, Describes signaling partnership of integrin and proteoglycan fibronectin receptors in regulating focal contact formation and provides data that protein kinase C can substitute for the proteoglycan receptor.
-
(1992)
J Cell Sci
, vol.101
, pp. 277-290
-
-
Woods1
Couchman2
-
20
-
-
0026731793
-
Fibronectin Fragments Cause Chondrolysis of Bovine Articular Cartilage Slices in Culture
-
of special interest, Informative example of an independent activity present in the amino-terminal 29 kD assembly domain of fibronectin that is not evident in the intact fibronectin molecule.
-
(1992)
J Biol Chem
, vol.267
, pp. 3597-3604
-
-
Homandberg1
Meyers2
Xie3
-
21
-
-
0026601095
-
Stromelysin Generates a Fibronectin Fragment That Inhibits Schwann Cell Proliferation
-
(1992)
J Cell Biol
, vol.116
, pp. 177-185
-
-
Muir1
Manthorpe2
-
23
-
-
0027021703
-
Signal transduction via the fibronectin receptor: do integrins regulate matrix remodeling?
-
of special interest, This short article and [22] document the regulation of metalloproteinase gene expression by fibronectin. These studies indicate the need for interaction of the cell with at least two domains on fibronectin for control of metalloproteinase expression.
-
(1992)
Matrix Suppl
, pp. 184-191
-
-
Damsky1
Tremble2
Werb3
-
24
-
-
0026605281
-
Degradation of Fibronectin and Vitronectin in Chronic Wound Fluid: Analysis by Cell Blotting, Immunoblotting, and Cell Adhesion Assays
-
of special interest, Documents the presence of fragments of fibronectin in wound fluids. The fragment size present differs in acute healing and chronic non-healing wounds.
-
(1992)
J Invest Dermatol
, vol.98
, pp. 410-416
-
-
Grinnell1
Ho2
Wysocki3
-
26
-
-
0025823515
-
Extracellular Proteins That Modulate Cell-Matrix Interactions
-
(1991)
J Biol Chem
, vol.266
, pp. 14831-14834
-
-
Sage1
Bornstein2
-
28
-
-
0025954786
-
Interaction of the Small Proteoglycan Decorin with Fibronectin — Involvement of the Sequence NKISK of the Core Protein
-
(1991)
Biochem J
, vol.280
, pp. 411-414
-
-
Schmidt1
Hausser2
Kresse3
-
29
-
-
0025999292
-
Relationship between Neuronal Migration and Cell-Substratum Adhesion: Laminin and Merosin Promote Olfactory Neuronal Migration but Are Anti-adhesive
-
of special interest, An interesting example of the importance of low affinity cell-ECM interactions in regulating cell behaviour.
-
(1991)
J Cell Biol
, vol.115
, pp. 779-794
-
-
Calof1
Lander2
-
31
-
-
0025734407
-
Disruption of the Actin Cytoskeleton after Microinjection of Proteolytic Fragments of α-Actinin
-
of special interest, This paper clearly documents the importance of α-actinin in maintaining the integrity of focal contacts.
-
(1991)
J Cell Biol
, vol.114
, pp. 481-491
-
-
Pavalko1
Burridge2
-
32
-
-
0026642556
-
1 Cytoplasmic Domain Implicated in Cytoskeletal Association
-
of special interest, Detailed mapping of sites in the β1 integrin cytoplasmic domain that are important for localization of integrin complexes to focal contacts, together with a thoughtful discussion of the structural and functional implications of several of the specific changes.
-
(1992)
J Cell Biol
, vol.117
, pp. 1321-1330
-
-
Reszka1
Hayashi2
Horwitz3
-
33
-
-
0026535449
-
Regulation of Fibronectin Receptor Distribution
-
of special interest, Clear demonstration that all information needed for localization of β1 integrin complexes to focal contacts is in the cytoplasmic domain of the β1-subunit. Raises the possibility that an important function of the α-subunit cytoplasmic domain is to restrict access of the β1 cytoplasmic domain to the cytoskeleton in the absence of binding of the complex to an appropriate immobilized ligand.
-
(1992)
J Cell Biol
, vol.117
, pp. 437-447
-
-
LaFlamme1
Akiyama2
Yamada3
-
35
-
-
0026596337
-
Distinct Cellular Functions Mediated by Different VLA Integrin α-Subunit Cytoplasmic Domains
-
of special interest, Clear example of the importance of information present in the cytoplasmic domains of integrins to interpretation by the intracellular signaling machinery of cell interactions with a specific substrate.
-
(1992)
Cell
, vol.68
, pp. 1051-1060
-
-
Chan1
Kassner2
Schiro3
Byers4
Kupper5
Hemler6
-
36
-
-
0026069822
-
In Vitro Interaction of a Polypeptide Homologous to Human Ro/SS-A Antigen (Calreticulin) with a Highly Conserved Amino Acid Sequence in the Cytoplasmic Domain of Integrin α-Subunits
-
of special interest, First report of a cytoplasmic component that appears to associate specifically with the α-subunits of integrins.
-
(1991)
Biochemistry
, vol.30
, pp. 9859-9866
-
-
Rojiani1
Finlay2
Gray3
Dedhar4
-
37
-
-
0026612521
-
FAK, A Structurally Distinctive Protein Tyrosine Kinase Associated with Focal Adhesions
-
of outstanding interest, 2nd edn., Cloning of FAK, a protein tyrosine kinase that is associated with cytoskeleton in platelets and with focal contacts in fibroblasts. This tyrosine kinase has an unusual sequence that indicates the importance of the cytoskeleton in the signaling mechanism of adhesion receptors.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5192-5196
-
-
Schaller1
Borgman2
Cobb3
Vines4
Reynolds5
Parsons6
-
38
-
-
0024327617
-
Association of Type 3 Protein Kinase C with Focal Contacts in Rat Embryo Fibroblasts
-
(1989)
J Cell Biol
, vol.109
, pp. 697-704
-
-
Jaken1
Leach2
Klauck3
-
40
-
-
0026249489
-
Fibronectin/Integrin Interaction Induces Tyrosine Phosphorylation of a 120-kDa Protein
-
of special interest, These authors and Komberg et al. [41⊎] document phosphorylation of specific proteins in response to fibronectin-integrin interactions. Data indicate that interactions with multiple domains of fibronectin may be necessary to obtain maximum phosphorylation, indicating the need for cooperation among fibronectin receptors.
-
(1991)
Cell Regul
, vol.2
, pp. 951-964
-
-
Guan1
Trevithick2
Hynes3
-
42
-
-
0026778133
-
The Small GTP-binding Protein rho Regulates the Assembly of Focal Adhesions and Actin Stress Fibers in Response to Growth Factors
-
of outstanding interest, Presents strong evidence that G proteins act as intermediates in regulating formation of stress fibers at focal contact sites.
-
(1992)
Cell
, vol.70
, pp. 389-399
-
-
Ridley1
Hall2
-
43
-
-
84909831916
-
c-src to Integrin-Dependent Cytoskeletal Complexes in Thrombin-Stimulated Platelets
-
of outstanding interest, in press, Documents a requirement for αllbβ3-fibrinogen binding in thrombin-induced activation and cytoskeletal association of pp60c-src in platelets. Again demonstrates the receptor partnership concept in signaling by adhesion receptors, and suggests that their role includes assembly of a cytoskeletal framework for localization of a signaling complex.
-
(1992)
Mol Cell Biol
-
-
Clark1
Brugge2
-
44
-
-
0025775939
-
Membrane Glycoprotein IV (CD36) Is Physically Associated with the Fyn, Lyn and Yes Protein-Tyrosine Kinases in Human Platelets
-
of special interest, 2nd edn., Documents the importance of adhesion receptor partnerships in signal transduction in platelets. GPIV (a thrombospondin receptor) can associate with tyrosine kinases in a putative signaling complex, but not if the integrin αIIbβ3 fibrinogen receptor does not bind its ligand.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7844-7848
-
-
Huang1
Bolen2
Barnwell3
Shattil4
Brugge5
-
45
-
-
0025880916
-
G1/S Control of Anchorage-independent Growth in the Fibroblast Cell Cycle
-
of special interest, First analysis of the cell cycle with the goal of determining the location of the anchorage requirement for the growth of normal fibroblasts. The site is in late G1, a point analogous to the START site in the yeast cell cycle.
-
(1991)
J Cell Biol
, vol.115
, pp. 1419-1425
-
-
Guadagno1
Assoian2
-
48
-
-
0026773942
-
+ Antiporter by PDGF
-
+ antiporter. This work initiates dissection of the sites in the protein kinase C pathway at which the integrin and the growth factor act.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 6138-6141
-
-
Schwartz1
Lechene2
-
50
-
-
0025786161
-
Control of Mammary Epithelial Differentiation: Basement Membrane Induces Tissue-specific Gene Expression in the Absence of Cell-Cell Interaction and Morphological Polarity
-
of special interest, Demonstrates that expression of milk proteins by mammary epithelial cells requires integrin-mediated contact with the basement membrane, as well as lactogenic hormones: a clear case of cooperative integrin signaling in the expression of tissue-specific genes.
-
(1991)
J Cell Biol
, vol.115
, pp. 1383-1395
-
-
Streuli1
Bailey2
Bissell3
-
51
-
-
0027057123
-
A Novel Transcriptional Enhancer Is Involved in the Prolactin and ECM-dependent Regulation of β-Casein Gene Expression
-
of outstanding interest, Presents evidence that a tissue-specific gene whose expression is responsive to ECM has a unique enhancer element that regulates its transcription.
-
(1992)
Mol Biol Cell
, vol.3
, pp. 699-709
-
-
Schmidhauser1
Casperson2
Myers3
Sanzo4
Bolten5
Bissell6
-
52
-
-
0026768210
-
Coordinated expression of extracellular matrix-degrading proteinases and their inhibitors regulates mammary epithelial function during involution
-
of special interest, in press, Provides a direct in vivo test of the hypothesis that basement membrane integrity affects tissue-specific function in this tissue.
-
(1992)
The Journal of Cell Biology
, vol.118
-
-
Talhouk1
Bissell2
Werb3
-
54
-
-
0025985299
-
Expression of β-1, β-3, β-4, and β-5-Integrins by Human Epidermal Keratinocytes and Non-Differentiating Keratinocytes
-
(1991)
J Cell Biol
, vol.115
, pp. 829-841
-
-
Adams1
Watt2
-
56
-
-
0026571678
-
Distribution Patterns of Extracellular Matrix Components and Adhesion Receptors Are Intricately Modulated during First Trimester Cytotrophoblast Differentiation along the Invasive Pathway, in Vivo
-
(1992)
J Clin Invest
, vol.89
, pp. 210-222
-
-
Damsky1
Fitzgerald2
Fisher3
-
58
-
-
0026510747
-
A Potential Fusion Peptide and an Integrin Ligand Domain in a Protein Active in Sperm-Egg Fusion
-
of outstanding interest, Demonstration that sperm-egg interaction and fusion is mediated by a transmembrane dimer on the sperm, in which one subunit has RGD-like sequences found in both matrix ligands and snake venoms, while the other has a fusion peptide. Indicates that integrin receptors are likely to be present on the egg membrane, and is the first demonstration of the existence of membrane-associated integrin ligands. See Blobel and White, this issue, pp 760–765.
-
(1992)
Nature
, vol.356
, pp. 248-252
-
-
Blobel1
Wolfsberg2
Turck3
Myles4
Primakoff5
White6
-
59
-
-
0025896188
-
Identification of the Fibronectin Sequences Required for Assembly of a Fibrillar Matrix
-
of special interest, Clear analysis using cloned fragments of the region of fibronectin that is required for matrix assembly.
-
(1991)
J Cell Biol
, vol.113
, pp. 1463-1473
-
-
Schwarzbauer1
-
60
-
-
0026593295
-
Differential Expression of Cell Surface Heparan Sulfate Proteoglycans in Human Mammary Epithelial Cells and Lung Fibroblasts
-
of special interest, As roles for proteoglycans in adhesion and regulation of growth factor function become more defined, analysis of their expression patterns becomes increasingly important.
-
(1992)
J Biol Chem
, vol.267
, pp. 1116-1122
-
-
Lories1
Cassiman2
Van den Berghe3
David4
-
61
-
-
0026762840
-
Cell Surface Phosphatidylinositol-anchored Heparan Sulfate Proteoglycan Initiates Mouse Melanoma Cell Adhesion to a Fibronectin-derived, Heparin-binding Synthetic Peptide
-
of special interest, Documentation of a phosphatidylinositol-linked surface heparan sulfate proteoglycan as a receptor for a particular region in the fibronectin carboxyl-terminal heparin-binding domain.
-
(1992)
J Cell Biol
, vol.117
, pp. 1331-1341
-
-
Drake1
Klein2
Mickelson3
Oegema4
Furcht5
McCarthy6
-
66
-
-
0026322616
-
Cytotactin Binding: Inhibition of Stimulated Proliferation and Intracellular Alkalinization in Fibroblasts
-
2nd edn.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11403-11407
-
-
Crossin1
-
70
-
-
0026527577
-
Integrin Modulating Factor-1: A Lipid That Alters the Function of Leukocyte Integrins
-
of outstanding interest, Identification and characterization of a small fatty acid that is synthesized under conditions that activate leukocyte integrins. Data suggest that integrin activation is regulated by the synthesis of this molecule.
-
(1991)
Cell
, vol.68
, pp. 341-352
-
-
Hermanowski-Vosatka1
Van Strijp2
Swiggard3
Wright4
-
71
-
-
0027082946
-
Spreading of HeLa Cells on a Collagen Substratum Requires a Second Messenger Formed by the Lipoxygenase Metabolism of Arachidonic Acid Released by Collagen Receptor Clustering
-
(1992)
Mol Biol Cell
, vol.3
, pp. 481-492
-
-
Chun1
Jacobsen2
-
72
-
-
0025666501
-
Integrin-associated Protein: a 50-kD Plasma Membrane Antigen Physically and Functionally Associated with Integrins
-
(1990)
J Cell Biol
, vol.111
, pp. 2785-2794
-
-
Brown1
Hooper2
Ho3
Gresham4
-
75
-
-
0025932687
-
Identification of a Novel Recognition Sequence for the Integrin α4β1 in the COOH-Terminal Heparin-Binding Domain of Fibronectin
-
(1991)
EMBO J
, vol.10
, pp. 4089-4095
-
-
Mould1
Humphries2
|