Genetic and biochemical analysis of vesicular traffic in yeast

Current Opinion in Cell Biology

Volumn 4, Issue 4, 1992, Pages 587-592

  Schekman, Randy ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOSOME;

GENETICS; MEMBRANE FUSION; METABOLISM; MUTATION; PHYSIOLOGY; REVIEW; SACCHAROMYCES CEREVISIAE; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; LIPOSOMES; MEMBRANE FUSION; MUTATION; SACCHAROMYCES CEREVISIAE;

EID: 0026908303     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0955-0674(92)90076-O     Document Type: Article

References (65)

1. Assembly of Yeast Sec Proteins Involved in Translocation into the Endoplasmic Reticulum into a Membrane-bound Multisubunit Complex
2. A Subfamily of Stress Proteins Facilitates Translocation of Secretory and Mitochondrial Precursor Proteins
3. Loss of BiP/GRP78 Function Blocks Translocation of Secretory Proteins in Yeast
4. The Signal Recognition Particle in S. cerevisiae
5. SEC11 is Required for Signal Peptide Processing and Yeast Cell Growth
6. Yeast Signal Peptidase Contains a Glycoprotein and the SEC11 Gene Product
7. Distinct Sets of SEC Genes Govern Transport Vesicle Formation and Fusion Early in the Secretory Pathway
8. Protein Sorting in S. cerevisiae. Isolation of Mutants Defective in the Delivery and Processing of Multiple Vacuolar Hydrolases
9. Characterization of Genes Required for Protein Sorting and Vacuolar Function in the Yeast Saccharomyces cerevisiae
10. ERD2, a Yeast Gene Required for the Receptor-mediated Retrieval of Luminal ER Proteins from the Secretory Pathway
11. The ERD2 Gene Determines the Specificity of the Luminal ER Protein Retention System
12. Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein
13. Order of events in the yeast secretory pathway
14. A ras-like protein is required for a post-Golgi event in yeast secretion
15. Mutational Analysis of SEC4 Suggests a Cyclical Mechanism for the Regulation of Vesicular Traffic
16. A GTP-binding Protein Required for Secretion Rapidly Associates with Secretory Vesicles and the Plasma Membrane in Yeast
17. A Mammalian Inhibitory GTP/GTP Exchange Protein (GDP Dissociation Inhibitor) for smg p25A is Active on the Yeast SEC4 Protein
18. Requirement of GTP Hydrolysis of the Signal Recognition Particle from Its Receptor
19. The Yeast GTP-binding YPT1 Protein and a Mammalian Counterpart are Associated with the Secretion Machinery
20. Study of a Temperature-sensitive Mutant of the ras-related YPT1 Gene Product in Yeast Suggests a Role in the Regulation of Intracellular Calcium
21. The GTP-binding Protein YPT1 is Required for Transport in Vitro the Golgi Apparatus is Defective in YPT1 Mutants
22. 2+ Function Independently in a Cell-free Protein Transport Reaction
23. Distinct Biochemical Requirements for the Budding, Targeting, and Fusion of ER-derived Transport Vesicles
24. Identification and Structure of Four Yeast Genes (SLY) that Are Able to Suppress the Functional Loss of YPT1, a Member of the RAS Superfamily
25. The Yeast SLY Gene Products, Suppresors of Defects in the Essential GTP-binding YPT1 Protein, May Act in Endoplasmic Reticulum-to-Golgi Transport
26. ADP-ribosylation Factor is Functionally and Physically Associated with the Golgi Complex
27. ADP-ribosylation Factor is a Subunit of the Coat of Golgi-derived COP-coated Vesicles: A Novel Role for a GTP-binding Protein
28. Co-operative binding of hsp60 may promote transfer hsp70 and correct folding of imported proteins in mitochondria
29. Binding of ARF and β-COP to Golgi Membranes: Possible Regulation by a Trimeric G Protein
30. The Human Rab Genes Encode a Family of GTP-binding Proteins Related to the Yeast YPT1 and SEC4 Products Involved in Secretion
31. Localization of Low-molecular Weight GTP-binding Proteins to Exocytic and Endocytic Compartments
32. Rab5 Controls Early Endosome Fusion in Vitro
33. Synthetic Peptides of the rab Effect or Domain Inhibit Vesicular Transport Through the Secretory Pathway
34. Involvement of GTP-binding “G” proteins in transport through the Golgi stack
35. Dissection of a Single Round of Vesicular Transport: Sequential Intermediates for Intercisternal Movement in the Golgi Stack
36. All ras Proteins are Polyisoprenylated but only Some are Palmitylated
37. Genetic and Pharmacological Suppression of Oncogenic Mutations in ras Genes of Yeast and Humans
38. A Carboxy-terminal Cysteine Residue is Required for Palmitic Acid Binding and Biological Activity of the ras-related YPT1 Protein
39. Dependence of YPT1 and SEC4 Membrane Attachment on Bet2
40. Structural Homology Among Mammalian and Saccharomyces cerevisiae Isoprenyl-protein Transferases
41. Protein geranylgeranyltransferase of Saccharomyces cerevisiae is specific for Cys-Xaa-Xaa-Leu motif proteins and requires the CDC43 gene product but not the DPR1 gene product.
42. Nucleotide Binding and Cofactor Activities of Purified Bovine Brain and Bacterially Expressed ADP-ribosylation Factor
43. Hypervariable C-terminal Domain of Rab Acts as a Targeting Signal
44. Purification of an N-ethylmaleimide-sensitive Protein Catalyzing Vesicular Transport
45. SNAPs, a Family of NSF Attachment Proteins Involved in Intracellular Membrane Fusion in Animals and Yeast
46. Vesicular Transport Between the Endoplasmic Reticulum and the Golgi Stack Requires an NEM-sensitive Fusion Protein
47. Vesicle Fusion Following Receptor-mediated Endocytosis Requires a Protein Active in Golgi Transport
48. A Fusion Protein Required for Vesicle-mediated Transport in Both Mammalian Cells and Yeast
49. The Yeast SEC17 Gene Product is Functionally Equivalent to Mammalian α-SNAP Protein
50. A Multisubunit Particle Implicated in Membrane Fusion
51. A Membrane Glycoprotein, Sec12p, Required for Protein Transport from the Endoplasmic Reticulum to the Golgi Apparatus in Yeast
52. Structural and Functional Dissection of a Membrane Gycoprotein Required for Vesicle Budding from the Endoplasmic Reticulum
53. A Novel GTP-binding Protein Sar1p Is Involved in Transport from the ER to the Golgi Apparatus
54. Sec12p-dependent Membrane Binding of the Small GTP-binding Protein Sar1p Promotes Formation of Transport Vesicles from the ER
55. Reconstitution of GTP-binding Sar1 Protein Function in ER to Golgi Transport
56. Yeast Sec23p Acts in the Cytoplasm to Promote Protein Transport from the Endoplasmic Reticulum to the Golgi Complex in Vivo and in Vitro
57. Sec23p and a Novel 105 kD Protein Function as a Multimeric Complex to Promote Vesicle Budding and Protein Transport from the ER
58. Mammalian Sec23p homolog is Restricted to the Endoplasmic Reticulum Transitional Cytoplasm
59. Functional Compartments of the Yeast Golgi Apparatus are Defined by the sec7 Mutation
60. Localization of Components Involved in Protein Transport and Processing through the Yeast Golgi Apparatus
61. Immunolocalization of Kex2 Protease Identifies a Putative Late Golgi Compartment in the Yeast Saccharomyces cerevisiae
62. Immuno-isolation of Sec7p-coated Transport Vesicles from the Yeast Secretory Pathway
63. An Essential Role for a Phospholipid Transfer Protein in Yeast Golgi Function
64. Mutations in the CDP-choline Pathway for Phospholipid Biosynthesis Bypass the Requirement for an Essential Phospholipid Transfer Protein