Mutation in mitochondrial tRNALeu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness

Nature Genetics

Volumn 1, Issue 5, 1992, Pages 368-371

  van den Ouweland, J M W ^a   Lemkes, H H P J ^b   Ruitenbeek, W ^c   Sandkuijl, L A ^d   de Vijlder, M F ^b   Struyvenberg, P A A ^b   van de Kamp, J J P ^b   Maassen, J A ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE TRANSFER RNA; MITOCHONDRIAL DNA; OLIGODEOXYRIBONUCLEOTIDE; RNA; RNA, MITOCHONDRIAL;

ADULT; ARTICLE; CASE REPORT; CELL CULTURE; CHILD; FEMALE; GENETICS; HEARING IMPAIRMENT; HELA CELL; HETEROZYGOTE DETECTION; HOMOZYGOTE; HUMAN; ISOLATION AND PURIFICATION; MALE; METABOLISM; MOLECULAR GENETICS; MUSCLE; NON INSULIN DEPENDENT DIABETES MELLITUS; NUCLEOTIDE SEQUENCE; PEDIGREE; POINT MUTATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RESTRICTION MAPPING;

BASE SEQUENCE; CASE REPORT; CELLS, CULTURED; CHILD; DEAFNESS; DIABETES MELLITUS, NON-INSULIN-DEPENDENT; DNA, MITOCHONDRIAL; FEMALE; HELA CELLS; HETEROZYGOTE DETECTION; HOMOZYGOTE; HUMAN; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; MUSCLES; OLIGODEOXYRIBONUCLEOTIDES; PEDIGREE; POINT MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RESTRICTION MAPPING; RNA; RNA, TRANSFER, LEU; SUPPORT, NON-U.S. GOV'T;

EID: 0026906885     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng0892-368     Document Type: Article

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