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Journal of Computer-Aided Molecular Design

Volumn 6, Issue 1, 1992, Pages 61-78

The computer program LUDI: A new method for the de novo design of enzyme inhibitors

(1) Böhm, Hans Joachim a

a BASF SE (Germany)

Author keywords

De novo design; Drug design; Enzyme inhibitors; Enzymes; Molecular modeling

Indexed keywords

BENZAMIDINE; BENZAMIDINE DERIVATIVE; DIHYDROFOLATE REDUCTASE; ENZYME; ENZYME INHIBITOR; FOLIC ACID ANTAGONIST; METHOTREXATE; TRYPSIN INHIBITOR;

ALGORITHM; ARTICLE; BINDING SITE; CHEMISTRY; COMPUTER PROGRAM; DRUG DESIGN;

ALGORITHMS; BENZAMIDINES; BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; ENZYMES; FOLIC ACID ANTAGONISTS; METHOTREXATE; SOFTWARE; TETRAHYDROFOLATE DEHYDROGENASE; TRYPSIN INHIBITORS;

EID: 0026813925 PISSN: 0920654X EISSN: 15734951 Source Type: Journal
DOI: 10.1007/BF00124387 Document Type: Article

Times cited : (809)

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