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Isolation of the Human cdk2 Gene that Encodes the Cyclin A- and Adenovirus E1A-associated p33 Kinase
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Nature
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Tsai1
Harlow2
Meyerson3
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11
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A New Human p34 Protein Kinase, CDK2, identified by Complementation of a cdc28 Mutation in Saccharomyces Cerevisiae, is a Homolog of Xenopus Eg1
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EMBO J
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Elledge1
Spottswood2
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Human Cyclin-dependent Kinase 2 (CDK2) is Activated in the S and G2 Phases of the Cell Cycle and Associates with Cyclin A
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(1992)
Proc Natl Acad Sci U S A
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Rosenblatt1
Gu2
Morgan3
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14
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0025831974
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Evidence that the G1-S and G2-M Transitions are Controlled by Different cdc2 Proteins in Higher Eukaryotes
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(1991)
Cell
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Fang1
Newport2
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17
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0026049598
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Transcriptional Activation of CLN1, CLN2, and a Putative New G1 Cyclin (HCS26) by SW14, a Positive Regulator of G1-specific Transcription
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of outstanding interest, The transcription of CLN1, CLN2, and another putative cyclin is dependent on SW14, a G1-specific transcription factor dependent on CDC28. Together with [45,46,47], supports the idea that CLN1 and CLN2 promote their own transcription through a positive feedback loop.
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(1991)
Cell
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Ogas1
Andrews2
Herskowitz3
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19
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DAF1, a Mutant Gene Affecting Size Control, Pheromone Arrest, and Cell Cycle Kinetics of Saccharomyces cerevisiae
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Dominoes and Clocks: the Union of Two Views of the Cell Cycle
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Science
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Murray1
Kirschner2
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25
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The Clam Embryo Protein Cyclin A Induces Entry into M Phase and the Resumption of Meiosis in Xenopus Oocytes
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Swenson1
Farrell2
Ruderman3
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The Roles of Drosophila Cyclins A and B in Mitotic Control
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Cell
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Lehner1
O'Farrell2
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27
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The A- and B-type Cyclin Associated cdc2 Kinases in Xenopus Turn on and off at Different Times in the Cell Cycle
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EMBO J
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Golsteyn2
Hill3
Hunt4
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28
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Human Cyclin A is Adenovirus E1A-associated Protein p60 and Behaves Differently from Cyclin B
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Nature
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Pines1
Hunter2
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31
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0025893161
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Cell Cycle Regulation of the E2F Transcription Factor Involves an Interaction with Cyclin A
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of special interest, The formation of complexes between E2F and Cyclin A during S phase is disrupted by the E1A transforming protein, perhaps contributing to loss of growth control.
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(1991)
Cell
, vol.65
, pp. 1243-1253
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Mudry1
Devoto2
Hiebert3
Hunter4
Pines5
Nevins6
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32
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0025917231
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Cyclin A and the Retinoblastoma Gene Product Complex with a Common Transcription Factor
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of special interest, Cyclin A associates with the DRTF1 transcription factor, and this association may be required to allow DRTF1 to bind the retinoblastoma gene product.
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(1991)
Nature
, vol.352
, pp. 249-251
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-
Bandara1
Adamczewski2
Hunt3
La Thangue4
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33
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-
0025806904
-
A Novel Cyclin Encoded by a bct1-linked Candidate Oncogene
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of outstanding interest, Evidence suggesting that overexpression of Cyclin D1 may contribute to loss of growth control in benign parathyroid tumors. Also shows that Cyclin D1 can stimulate CDK kinase activity when added to clam embryo lysates.
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(1991)
Nature
, vol.350
, pp. 512-515
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Motokura1
Bloom2
Kim3
Juppner4
Ruderman5
Kronenberg6
Arnold7
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34
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0025819962
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Colony-stimulating Factor 1 Regulates Novel Cyclins during the G1 Phase of the Cell Cycle
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of outstanding interest, Best demonstration thus far of a connection between growth factor action and cell cycle control. Demonstrates that Cyclin D1 is a serum-dependent, unstable protein present throughout the cell cycle.
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(1991)
Cell
, vol.65
, pp. 701-713
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Matsushime1
Roussel2
Ashmun3
Sherr4
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35
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Human D-type Cyclin
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of special interest, Isolation of human Cyclin D1 by complementation of a triple CLN deletion in S. cerevisiae.
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(1991)
Cell
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Xiong1
Connolly2
Futcher3
Beach4
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36
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Isolation of Three Novel Human Cyclins by Rescue of C1 Cyclin (Cln) Function in Yeast
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of outstanding interest, Isolation of human Cyclins C, D and E by complementation of the triple CLN deletion, with Northern analysis demonstrating G1 expression of Cyclins C and E.
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(1991)
Cell
, vol.66
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Lew1
Dulic2
Reed3
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37
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0025734356
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Human Cyclin E, a new Cyclin that Interacts with Two Members of the CDC2 Gene Family
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of outstanding interest, Isolation of human Cyclin E, plus interesting studies in yeast showing that it can interact with human CDC2 or CDK2 to stimualte passage through Start. Includes a biochemical demonstration of Cyclin E-associated kinase activity.
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(1991)
Cell
, vol.66
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Koff1
Cross2
Fisher3
Schumacher4
Leguellec5
Philippe6
Roberts7
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39
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0026027660
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cdc2 Kinase at the G1/S and G2/M Transitions of the Cell Cycle: Identification of Major Phosphorylation Sites
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of special interest, Thorough analysis of CDC2 phosphorylation sites during the higher eukaryotic cell cycle.
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EMBO J
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Krek1
Nigg2
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40
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0024390591
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Reversible Tyrosine Phosphorylation of cdc2: Dephosphorylation Accompanies Activation during Entry into Mitosis
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Cell
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Morla1
Draetta2
Beach3
Wang4
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0024959919
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(1989)
Nature
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Gould1
Nurse2
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42
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0027007963
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cdc2 Activation: Identification of an Activating Kinase
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of special interest, Phosphorylation of CDC2 on a threonine residue is required for CDC2 activation in Xenopus embryo extracts; the phosphorylation is probably catalyzed by a separate kinase.
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(1992)
Mol Biol Cell
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Solomon1
Lee2
Kirschner3
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43
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Regulated Expression and Phosphorylation of a Possible Mammalian Cell-cycle Control Protein
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Nature
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Lee1
Norbury2
Spurr3
Nurse4
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44
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Identification of a Gene Necessary for Cell Cycle Arrest by a Negative Growth Factor of Yeast: FAR1 is an Inhibitor of a G1 Cyclin, CLN2
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Cell
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Chang1
Herskowitz2
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45
-
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0025753691
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A Potential Positive Feedback Loop Controlling CLN1 and CLN2 Gene Expression at the Start of the Yeast Cell Cycle
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(1991)
Cell
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Cross1
Tinkelenberg2
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46
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0026432655
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Positive Feedback in the Activation of G1 Cyclins in Yeast
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Nature
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Dirick1
Nasmyth2
-
47
-
-
0025944525
-
The Role of SWI4 and SWI6 in the Activity of G1 Cyclins in Yeast
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of outstanding interest, This paper together with [46]provides a thorough analysis of CLN1, -2, and -3 regulation by the G1-specific transcription factors SWI4 and SWI6. More evidence that CLN1 and CLN2 expression is up-regulated by CDC28-CLN complexes in a positive feedback loop.
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(1991)
Cell
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Nasmyth1
Dirick2
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48
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0024442034
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A Putative Protein Kinase Overcomes Pheromone-induced Arrest of Cell Cycling in S. Cerevisiae
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Cell
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Courchesne1
Kunisawa2
Thorner3
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