Detection of cytokines at the cartilage/pannus junction in patients with rheumatoid arthritis: Implications for the role of cytokines in cartilage destruction and repair

Rheumatology

Volumn 31, Issue 10, 1992, Pages 653-661

  Chu, C Q ^a   Field, M ^a   Allard, S ^a   Abney, E ^a   Feldmann, M ^a   Maini, R N ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cartilage pannus junction; Cytokines; Rheumatoid arthritis

Indexed keywords

CHLORDANE; CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN F(AB) FRAGMENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 6; LYMPHOTOXIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BONE; CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROBLAST; HOMEOSTASIS; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; PANNUS; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIUM; VASCULAR ENDOTHELIUM;

ADULT; AGED; ARTHRITIS, RHEUMATOID; CARTILAGE, ARTICULAR; CYTOKINES; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MALE; MIDDLE AGE; MONOCYTES; SUPPORT, NON-U.S. GOV'T; SYNOVIAL MEMBRANE; TRANSFORMING GROWTH FACTOR BETA;

EID: 0026802287     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/31.10.653     Document Type: Article

References (53)

1. Shiozawa S, Shiozawa K. A review of the histopathological evidence on the pathogenesis of cartilage destruction in rheumatoid arthritis. Scand J Rheumatol 1988;Suppl 74:65-72.
2. Allard SA, Muirden KD, Camplejohn KL, Maini RN. Chondrocyte-derived cells and matrix at the rheumatoid cartilage-pannus junction identified with monoclonal antibodies. Rheumatol Int 1987; 7:153-9.
3. Woolley DE, Crossley M, Evanson JM. Collagenase at sites of cartilage erosion in the rheumatoid joint. Arthritis Rheum 1977;20:1231-9.
4. Feldmann M, Brennan FM, Chantry D et al. Cytokine production in the rheumatoid joint: implications for treatment. Ann Rheum Dis 1990;49:480-6.
5. Dinarello CA. Interleukin-1 and its biologically related cytokines. Adv Immunol 1989;44:153-205.
6. Gilman SC. Activation of rabbit articular chondrocytes by recombinant human cytokines. J Rheumatol 1987;14:1002-7.
7. Schnyder J, Payne T, Dinarello CA. Human monocyte or recombinant interleukin l’s are specific for the secretion of a metalloproteinase from chondrocytes. J Immunol 1987;138:496-503.
8. Shinmei M, Masuda K, Kikuchi T, Shimomura Y. Interleukin 1, tumour necrosis factor, and interleukin 6 as mediators of cartilage destruction. Semin Arthritis Rheum 1989;18(Suppl 1):27-32.
9. Dayer J-M, Beutler B, Cerami A. Cachectin/tumour necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts. J Exp Med 1985;162:2163-8.
10. Dayer J-M, de Rochemonteix B, Burrus B, Demcznk S and Dinarello CA. Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J Clin Invest 1986;77:645-8.
11. Tyler JA. Articular cartilage cultured with catabolin (pig interleukin 1) synthesizes a decreased number of normal proteglycan molecules. Biochem J 1985;227:869-78.
12. Saklatvala J. Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature 1986;322:547-9.
13. Nietfeld JJ, Wilbrink B, Helle M et al. Interleukin-1 induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage. Arthritis Rheum 1990; 33:1695-1701.
14. Alvaro-Gracia JM, Zvaifler NJ, Firestein GS. Cyto-kines in chronic inflammatory arthritis IV. Granulocyte/macrophage colony-stimulating factor-mediated induction of class II MHC antigen on human monocytes: A possible role in rheumatoid arthritis. J Exp Med 1989;170:865-75.
15. Haworth C, Brennan FM, Chantry D, Turner M, Maini RN, Feldmann M. Expression of granulocyte-macrophage colony stimulating factor (GM-CSF) in rheumatoid arthritis: Regulation by tumour necrosis factor a. Eur J Immunol 1991;10:2575-9.
16. Roberts AB, Sporn MB. Transforming growth factor beta. Adv Cancer Res 1988;51:107-145.
17. Chu CQ. Field M, Feldmann M, Maini RN. Localisation of tumour necrosis factor α in synovial tissues and at the cartilage/pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 1991; 34:1125-32.
18. Field M, Chu C, Feldmann M, Maini RN. Interleukin 6 localisation in the synovial membrane in rheumatoid arthritis. Rheumatol Int 1991:11:45-50.
19. Zheng R, Abney E, Chu CQ, et al. Detection of IL-6 and IL-1 production in human thyroid epithelial cells by non-radioactive in situ hybridization and immunohistochemical methods. Clin Exp Immunol 1991;83;314-19.
20. Chu CQ, Field M, Abney E et al. Transforming growth factor-ßl in rheumatoid synovial membrane and cartilage/pannus junction. Clin Exp Immunol 1991;86:380-6.
21. Arnett FC, Edworthy SM, Bloch DA et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
22. Mitchell NS, Shepard N. Changes in proteoglycan and collagen in cartilage in rheumatoid arthritis J Bone Joint Surg 1978;60A:349-54.
23. Kelly PMA, Bliss E, Morton JA, Burns J, McGee JOD. Monoclonal antibody EBM11: high cellular specificity for human macrophages. J Clin Pathol 1988;41:510-15.
24. Stevens CR, Mapp PI, Revell PA. A monoclonal anti-body (Mab 67) marks type B synoviocytes. Rheumatol Int 1990;10:103-6.
25. Poulter LW, Campbell DA, Munro C, Janossy G. Discrimination of human macrophages and dendritic cells by means of monoclonal antibodies. Scand J Immunol 1986;24:351-7.
26. Naiem M, Gerdes J, Abdulaziz Z et al. The value of immunohistological screening in the production of monoclonal antibodies. J Immunol Meth 1982; 50:145-60.
27. Klareskog L, Johnell O. Induced expression of class II transplantation antigens in the cartilage/pannus junction in RA: Chronic synovitis as a model system of aberrant T-lymphocyte activation. Br J Rheumatol 1988;27(suppl 2): 141-9.
28. Aarden LA, De Groot ER, Schaap OL, Lansdorp PM. Production of hybridoma growth factor by human monocytes Eur J Immunol 1987;17:1411-16.
29. Allard SA, Bayliss MT, Maini RN. The synovium-cartilage junction of the normal human knee. Arthritis Rheum 1990;33:1170-9.
30. Guerne PA, Carson DA, Lötz M. IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro. J Immunol 1990;144:499-505.
31. Chu CQ, Field M, Allard S, et al. Cytokine production at the cartilage/pannus junction (CPJ) in rheumatoid arthritis (RA). Clin Rheumatol 1990;9:572 (abstract).
32. Rosier RN, O’Keefe RJ, Crabb ID, Puzas JE. Trans-forming growth factor beta: An autocrine regulator chondrocytes. Connect Tissue Res 1989;20:295-301.
33. Ogawa Y, Sawamura SJ, Ksander GA, Armstrong RM, Pratt BM, McPherson JM. Transforming growth factor-beta 1 and beta 2 induce synthesis and accumulation of hyaluronate and chondroitin sulfate in vivo. Growth Factors 1990;3:53-62.
34. Iwamoto M, Koike T, Nakashima K, Sato K, Kato Y. Interleukin-1: a regulator of chondrocyte proliferation. Immunol Lett 1989;21:153-6.
35. Olivierre F, Gublert U, Towle CA, Laurencin C, Treadwell BV. Expression of IL-1 gene in human and bovin chondrocytes: A mechanism for autocrine control of cartilage matrix degradation. Biochem Biophys Res Comm 1986;141:904-11.
36. Smith RJ, Rohloff NA, Sam LM, Justen JM, Deibel MR, Cornette JC. Recombinant human interleukin-1 alpha and recombinant human interleukin-1 beta stimulate cartilage matrix degradation and inhibit glycosaminoglycan synthesis. Inflammation 1989;13:367-82.
37. Nietfeld JJ, Wilbrink B, den Otter W, Huber J and Huber-Bruning O. The effect of human interleukin 1 on proteoglycan metabolism in human and porcine cartilage explants. J Rheumatol 1990; 17:818-26.
38. O’Byrne EM, Blancuzzi V, Wilson DE, Wong M, Jeng AY. Elevated substance P and accelerated cartilage degradation in rabbit knees injected with interleukin-1 and tumour necrosis factor. Arthritis Rheum 1990;33:1023-8.
39. Wahl SM, McCartney-Francis N, Mergenhagen SE. Inflammatory and immunomodulatory roles of TGF-ß. Immunol Today 1989;10:258-61.
40. Roberts AB, Sporn MB, Assoian RK et al. Transforming growth factor type b: Rapid induction of fibrosis and angiogenis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 1986;83:4167-71.
41. Ignotz RA, Massague J. Transforming growth factor-ß stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem 1986;261:43337-45.
42. Lafyatis R, Thompson NL, Remmers EF et al. Transforming growth factor-ß production by synovial tissue from rheumatoid patients and streptococcal cell wall arthritic rats: studies on secretion by synovial fibroblast-Iike cells and immunohistologic localization. J Immunol 1989;143:1142-8.
43. Redini F, Galera P, Mauviel A, Loyau G, Pujol J-P. Transforming growth factor β stimulates collagen and glycosaminoglycan biosynthesis in cultured rabbit articular chondrocytes. FEBS Lett 1988; 234:172-6.
44. Morales TI and Roberts AB. Transforming growth factor β regulates the metabolism of proteoglycans in bovine cartilage organ cultures. J Biol Chem 1988;263:12828-31.
45. Edwards DR, Murphy G, Reynolds JJ et al. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J 1987;6:1899-1904.
46. Postlethwaite AE, Keski-Oja J, Moses HL, Kang AH. Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor-ß. J Exp Med 1987;165:251-6.
47. Allard SA, Muirden KD, Maini RN. Correlation of histological features of pannus with patterns of damage in different joints in rheumatoid arthritis. Ann Rheum Dis 1991;50:278-83.
48. Kohase M, Heriksen-DeStefano D, May LT, Vilcek J, Seghal PB. Induction of ß2-interferon by tumour necrosis factor: A homeostatic mechanism in the control of cell proliferation. Cell 1986;45:659-66.
49. Van Damme J, Opdenakker G, Simpson RJ et al. Identification of the human 26-KD protein, interferon ß2 (IFN-ß2), as a B cell hybridoma/plasmac-ytoma growth factor induced by interleukin I and tumour necrosis factor. J Exp Med 1987;165:914-19.
50. Guerne PA, Villiger P, Lötz M. Unique synergy and interactions between IL-6 and TGF-ß in the regulation of chondrocyte function. Clin Rheumatol 1990;9,527 (abstract).
51. Di Giovine FS, Poole S, Situnayake RD, Wadhwa M, Duff GW. Absence of correlations between indices of systemic inflammation and synovial fluid interleukin-1 (alpha and beta) in rheumatic diseases. Rheumatol Int 1990;9:259-64.
52. Covington M, Field M, Chu C, Feldmann M, Maini RN. Interleukin-1 (IL-1) localisation in rheumatoid arthritis (RA). Br J Rheumatol 1989;28 (suppl. 2):45.
53. Eastgate JA, Symons IA, Wood NC, Grinlinton FM, di Giovine FS, Duff GW. Correlation of plasma interleukin-1 levels with disease activity in rheumatoid arthritis. Lancet 1988;ii:706-9.