Rational Design and Molecular Effects of a New Topoisomerase II Inhibitor, Azatoxin

Cancer Research

Volumn 52, Issue 16, 1992, Pages 4478-4483

  Pommier, Yves ^a,c   Cuzi, Timothy J ^b   Lehnert, Erich ^b   Macdonald, Timothy ^b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ALKALOID; AZATOXIN; DNA TOPOISOMERASE (ATP HYDROLYSING); ELLIPTICINE DERIVATIVE; ENZYME INHIBITOR; ETOPOSIDE DERIVATIVE; GYRASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; BASE PAIRING; CELL FREE SYSTEM; DNA BINDING; DNA SEQUENCE; DNA STRAND BREAKAGE; DRUG DESIGN; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME INHIBITOR INTERACTION; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

DNA; DNA DAMAGE; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; DNA, SUPERHELICAL; DNA, VIRAL; DRUG DESIGN; HUMAN; INDOLES; PODOPHYLLOTOXIN; SIMIAN VIRUS 40; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026800754     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

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