In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers

International Journal of Pharmaceutics

Volumn 78, Issue 1-3, 1992, Pages 43-48

  Lehr, Claus Michael ^a   Bouwstra, Joke A ^a   Schacht, Etienne H ^b   Junginger, Hans E ^a  

^a Center for Bio Pharmaceutical Sciences Division of Pharmaceutical Technology ^*  (Netherlands)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Chitosan; Detachment force; Hydrogel; Mucoadhesion; Polycarbophil; Wash off test

Indexed keywords

CARBOXYMETHYLCELLULOSE; CHITOSAN; DAICHITOSAN; DEXTRAN T 70; DIETHYLAMINOETHYLDEXTRAN; HETASTARCH; HYDROXYPROPYLCELLULOSE; PECTIN; POLYCARBOPHIL; POLYMER; SCLEROGLUCAN; SEA CURE; UNCLASSIFIED DRUG; XANTHAN;

ADHESION; ANIMAL TISSUE; ARTICLE; DRUG SCREENING; HYDROGEL; INTESTINE MUCOSA; NONHUMAN; PIGEON; PRIORITY JOURNAL;

EID: 0026800237     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(92)90353-4     Document Type: Article

References (8)

1. Intestinal transit of bioadhesive microspheres in an in situ loop in the rat - A comparative study with copolymers and blends based on poly(acrylic acid)
2. Sustained-release and intragastric-floating granules of indomethacin using chitosan in rabbits
3. Mucoadhesive hydrogels effective at neutral pH
4. Surface, interfacial and molecular aspects of polymer bioadhesion on soft tissues
5. An in-vitro investigation of mucosa-adhesive materials for use in controlled drug delivery
6. Characteristics of polyion complexes of chitosan with sodium alginate and sodium polyacrylate