Simulation of crack propagation in tablet film coatings containing pigments

International Journal of Pharmaceutics

Volumn 78, Issue 1-3, 1992, Pages 49-57

  Rowe, R C ^a   Roberts, R J ^a  

^a AKZO NOBEL CENTRAL RESEARCH   (Netherlands)

Author keywords

Crack propagation; Film coating; Fracture; Pigment; Simulation

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE;

ARTICLE; DRUG COATING; FILM; MATHEMATICAL PARAMETERS; MODEL; PARTICLE SIZE; PRIORITY JOURNAL; SIMULATION; TABLET; TABLET DISINTEGRATION;

EID: 0026798239     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(92)90354-5     Document Type: Article

References (13)

1. Material behaviour at rapid loading - old thoughts revisited
2. Computer demonstration of crack growth
3. The propagation of cracks and crack like defects in thin adhered polymer films
4. A cracked elastic strip bonded to a rigid support
5. Mechanical properties of pigmented tablet coating formulations and their resistance to cracking. I: Static mechanical measurement
6. Tablet coating — problems with film coating
7. The practical significance of the permeability and mechanical properties of polymer films used for the coating of pharmaceutical solid dosage forms
8. The cracking of film coatings on film coated tablets — a theoretical approach with practical implications
9. A comment on the localised cracking around pigment particles in film coatings applied to tablets
10. The effect of pigment type and concentration on the incidence of edge splitting on film coated tablets
11. Materials used in the film coating of oral dosage forms
12. Localised cracking around pigment particles in tablet film coating — a theoretical approach