Kynostatin (kni)-227 And -272, Highly Potent Anti-hiv Agents: Conformationally Constrained Tripeptide Inhibitors of Hiv Protease Containing Allophenylnorstatine1'2)

Chemical and Pharmaceutical Bulletin

Volumn 40, Issue 8, 1992, Pages 2251-2253

  Mimoto, Tsutomu ^a   Imai, Junya ^a   Kisanuki, Sumitsugu ^a   Enomoto, Hiroshi ^a   Akaji, Kenichi ^a   Kiso, Yoshiaki ^a   Hattori, Naoko ^b  

^a KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^b Innovative Materials Development Center   (Japan)

Author keywords

AIDS; allophenylnorstatine; anti HIV agent; hydroxymethylcarbonyl isostere; KEYWORDS HIV protease inhibitor; kynostatin; peptide synthesis; transition state mimic

Indexed keywords

A 77003; ANTIVIRUS AGENT; ENZYME INHIBITOR; KNI 227; KYNOSTATIN 227; KYNOSTATIN 272; PROTEINASE INHIBITOR; TRIPEPTIDE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG DEVELOPMENT; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIVIRAL AGENTS; HIV PROTEASE INHIBITORS; HIV-1; OLIGOPEPTIDES;

EID: 0026793703     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.40.2251     Document Type: Article

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