Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons

Neuron

Volumn 9, Issue 3, 1992, Pages 449-463

  Schecterson, Leslayann C ^a   Bothwell, Mark ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED GROWTH FACTOR; NERVE GROWTH FACTOR; NEUROTROPIN;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; EMBRYO; FEMALE; GENE EXPRESSION; IN SITU HYBRIDIZATION; MOTONEURON; MOUSE; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN TRANSPORT; SENSORY GANGLION; SENSORY NERVE CELL; SYMPATHETIC GANGLION; SYMPATHETIC NERVE CELL;

ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; GANGLIA, SYMPATHETIC; MICE; MICE, INBRED BALB C; MOTOR NEURONS; MUSCLES; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEURONS; NEURONS, AFFERENT; NEUROTROPHIN 3; RECEPTORS, CELL SURFACE; RECEPTORS, NERVE GROWTH FACTOR; RNA, MESSENGER; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC;

EID: 0026787533     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/0896-6273(92)90183-E     Document Type: Article

References (57)

1. Detection of brain-derived neurotrophic factor like activity in fibroblasts and Schwann cells: inhibition by antibodies to NGF
2. Survival effect of ciliary neurotrophic: factor (CNTF) on chick embryonic motoneurons in' culture: comparison with other neurotrophic factors and cytokines
3. Cellular localization of nerve growth factor synthesis by in situ hybridization
4. Purification of a new neurotrophic factorfrom mammalian brain
5. Neurotrephin-5: a novel neurotrophic factor that activates trk and trkB
6. Constitutive and regulated secretion of proteins
7. Multiple functions for NGF receptor in developing, aging and injured rat teeth are suggested by epithelial, mesenchymal and neural immunoreactivity
8. Purification and metabolic effects of a nervegrowth promoting protein from the mouse salivary gland and its neurocytotoxic antiserum
9. The trk tyrosine ,protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3
10. Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes
11. An autoradiographicanalysis of the chick trigeminal ganglion
12. The response of chick sensory neurons to brain-derived neurotrophic factor
13. Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor
14. Immunohistochemical localisation of nerve growth factor-like protein in the organ of Corti of the developing rat
15. Processing and secretion of nerve growth factor: expression in mammalian cells with a vaccinia virus vector
16. Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons
17. Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain
18. TrkB mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low-affinity NGF receptor
19. Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary
20. High affinity NGF binding requires co-expression of the trk proto-oncogeneand the low affinity NGF receptor
21. Structure and developmental expression of the chicken receptor
22. Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues
23. Brain-derived neurotrophic factor prevents neuronal death in vivo
24. Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family
25. Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity
26. Expression and structure of the human NGF receptor
27. Characterization of the effects of autoimmune nerve growth factor deprivation in the developing guinea pig
28. Thetrk proto-oncogene product: a signal transducing receptor for nerve growth factor
29. Pathways of secretion
30. trk B, a novel tyrosine protein kinase receptor expressed during mouse neural development
31. The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain
32. Expression of the tyrosine kinase receptor gene trk B is confined to the murine embryonic and adult nervous system
33. The trk proto-oncogene encodes a receptor for nerve growth factor
34. trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3
35. Neuronotrophic effect of developing otic vesicle on cochleo-vestibular neurons: evidence for nerve growth factor involvement
36. Molecular cloning and expression of brain-derived neurotrophic factor
37. Placodal sensory neurons in culture: nodose ganglion neurons are unresponsive to NGF, lack NGF receptors but are supported by a liver-derived neurotrophic factor
38. Neurotrophin-3: a new neurotrophic factor related to NGF and BDNF
39. Expression of the trk proto-oncogene is restricted to sensory cranial and spinal ganglia of neural crest origin in mouse development
40. trkB, a neural receptor protein-tyrosine kinase: evidence for a full length and two truncated receptors
41. The control of avian cephalic neural crest cytodifferent iation. II. Neural tissues
42. Widespread expression of BDNF but not NT-3 by target areas of basal forebrain cholinergic neurons
43. Gene transfer and molecular cloning of the rat nerve growth factor receptor
44. Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
45. Primary structure and biological activity of a novel human neurotrophic factor
46. Expression of NGF receptor in developing and adult primate central nervous system
47. Regulation of neural cell adhesion molecule expression on cultured Schwann cells by nerve growth factor
48. Expression of the betanerve growth factor gene correlates with the density of sympathetic innervation of effector organs
49. trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor
50. Induction of nerve growth factor receptors in Schwann cells after axotomy
51. Expression of nerve growth factor receptors by Schwann cells of axotomized peripheral nerves
52. Expression of nerve growth factor (NGF) receptors in the developing inner ear of chick and rat
53. Retrograde transport of NGF by early chick embryo spinal cord motoneurons
54. Spatiotemporal patterns of expression of NGF and NGF receptor in rat embryos suggests functional roles in tissue morphogenesis and myogenesis
55. An immunohistochemical study of the nerve growth factor receptor in developing rats
56. Retrograde transport of nerve growth factor (NGF) in motoneurons of developing rats: assessment of potential neurotrophic effects
57. Neurotrophin-3: a neurotrophic factor related to NGF and BDNF