Bradykinin induces a B2 receptor-mediated calcium signal linked to prostanoid formation in human gingival fibroblasts in vitro

Agents and Actions

Volumn 37, Issue 1-2, 1992, Pages 44-52

  Lerner, U H ^a   Brunius, G ^b   Anduren, I ^b   Berggren, P O ^b   Juntti Berggren, L ^b   Modeer T ^b  

^a UMEÅ UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BRADYKININ; BRADYKININ B2 RECEPTOR; CALCIMYCIN; CALCIUM ION; INDOMETACIN; IONOMYCIN; PHORBOL DIBUTYRATE; PHORBOL DIDECANOATE; PROSTAGLANDIN E2; PROSTANOID;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; FIBROBLAST; GINGIVA; HUMAN; HUMAN CELL; INFLAMMATION; NORMAL HUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SCHOOL CHILD; SIGNAL TRANSDUCTION;

BRADYKININ; CALCIUM; CELLS, CULTURED; CHILD; CYTOPLASM; DINOPROSTONE; FIBROBLASTS; GINGIVA; HUMAN; RECEPTORS, BRADYKININ; RECEPTORS, NEUROTRANSMITTER; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T;

STAPHYLOCOCCUS PHAGE 187;

EID: 0026784214     PISSN: 00654299     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/BF01987889     Document Type: Article

References (27)

1. Kinin formation: Mechanisms and role in inflammatory and diabetic diseases
2. Pharmacology of kinins: Their relevance to tissue injury and inflammation
3. Mechanism of enhanced sensitivity to bradykinin in pertussis toxin-treated fibroblasts: Toxin increases bradykinin-stimulated prostaglandin formation
4. Thrombin and bradykinin enhance prostaglandin production in human peripheral blood monocytes
5. Bradykinin stimulates production of prostaglandin E2and prostacyclin in murine osteoblasts
6. Bradykinin stimulates prostaglandin E2formation in isolated human osteoblast-like cells
7. Bradykinin stimulates bone resorption and lysosomal-enzyme release in cultured mouse calvaria
8. The use of crevicular fluid prostaglandin E2levels as a predictor of periodontal attachment loss
9. Flurbiprofen: A potent inhibitor of alveolar bone resorption in beagles
10. Bradykinin, a new potential mediator of inflammation-induced bone resporption. Studies on the effects on mouse calvarial bones and articular cartilage in vitro
11. Bradykinin-2 receptor mediated release of3H-arachidonic acid and formation of prostaglandin E2in human gingival fibroblasts
12. Rapid activation of calmodulin-dependent protein kinase III in mitogen-stimulated human fibroblasts
13. Mitogen-induced [Ca2+]ichanges in individual human fibroblasts. Image analysis reveals asynchronous responses which are characteristic for different mitogens
14. Altered response of fibroblasts from aged and Alzheimer donors to drugs that elevate cytosolic free calcium
15. An increase in intracellular free Ca2+associated with serum-free growth stimulation of Swiss 3T3 fibroblasts by epidermal growth factor in the presence of bradykinin
16. The effect of the phenytoin metabolite p-HPPH on proliferation of gingival fibroblasts in vitro
17. The significance of calcium for glucose stimulation of insulin release
18. Glucosestimulated efflux of Fura-2 in pancreatic β-cells is prevented by probenecid
19. Stimulation of bone resorption in cultured mouse calvaria by Lys-bradykinin (kallidin), a potential mediator of bone resorption linking anaphylaxis processes to rarefying osteitis
20. Inositol phosphates and cell signalling
21. Pharmacology of bradykinin and related kinins
22. Competitive antagonists of bradykinin
23. Bradykinin induces formation of inositol phosphates and causes an increase in cytoplasmic Ca2+in the osteoblastic cell line MC3T3-El
24. Bradykinin-induced burst of prostaglandin formation in osteoblasts is mediated via B2 bradykinin receptors
25. How is the level of free arachidonic acid controlled in mammalian cells
26. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
27. Intracellular Ca2+and protein kinase C interact to regulate α1- adrenergic-and bradykinin receptor-stimulated phospholipase A2activation in Madin-Darby canine kidney cells