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Tetrahedron Letters
Volumn 33, Issue 21, 1992, Pages 2983-2986
Macrocarpals: HIV-RTase inhibitors of Eucalyptus globulus
Author keywords

Eucalyptus globulus; HIV RTase inhibitors; Macrocarpals A E; Structure Determination
Indexed keywords

ENZYME INHIBITOR; MACROCARPAL A; MACROCARPAL C; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;
EID: 0026773643     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)79578-5     Document Type: Article
Times cited : (93)
References (24)
  • 14
    • 84914382231 scopus 로고    scopus 로고
    • 5) δ 17.9 (C-14), 19.8 (C-11′), 20.9 [[Truncated]]
  • 15
    • 84914382230 scopus 로고    scopus 로고
    • 5) δ 0.65 (H-7, ddd, J = 10.9, 9.9, 6.4 Hz), 0.77 (H-6, dd, J 9.9, 9.9 Hz), 1.04 (H-13′, d, J = 6.2 Hz), 1.08 (H-12′, d, J = 6.2 Hz), 1.12 (H-8β, m), 1.17 (H-13, s), 1.29 (H-14, s), 1.37 (H-3α, m), 1.40 (s, H-15), 1.42 (H-12, s), 1.49 (H-5, dd, J = 9.9, 9.9 Hz), 1.60 (H-10′, 11′,m), 1.85 (H-3β, m) 1.92 (H-8α, 9α, m), 1.98 (H-2α, m), 2.05 (H-9β, ddd, J = 6.5, 6.5, 6.5 Hz), 2.17 (H-2β, m), 2.44 (H-1, ddd, J = 9.9, 9.9, 5.8 Hz), 2.78 (H-10′, ddd, J = 11.6, 11.6, 9.7 Hz), 3.70 (H-9′, dd, J = 113.2, 9.7 Hz), 10.54 (H-7′, s), 10.58 [[Truncated]]
  • 16
    • 0004328687 scopus 로고
    • Numbering of this class of compound confused. We choose numbering according to the biosynthetic stand point of sesquiterpene (1 to 15) and phloroglucinol (1′ to 14′). See, IUPAC, Pergamon Press, Oxford, See also ref. 3.
    • (1979) Nomenclature of Organic Chemistry , pp. 152
    • Rigaudy1    Klesney2
  • 18
    • 84914382229 scopus 로고    scopus 로고
    • 5) δ 17.1 (C-12), 20.1 (C-11), 22.0 (C-12′), 23.5 (C-15), 24.7 (C-13′), 25.8 (C-8), 27.2 (c-11′), 27.4 (C-6), 27.8 (C-2), 28.1 (C-7), 28.9 (C-13), [[Truncated]]
  • 19
    • 84914382228 scopus 로고    scopus 로고
    • 2O/pyridine provided two diastereomeric pentaacetates due to a hindered rotation around 6′–9′ bond. In which two acetyl groups were incorporated into an aldehyde group affording a diacetylacetal moiety (two acetyl methyls appeared around δ 2 as broad signals due to a restricted rotation around 2′–7′, or 4′–8′) bond, three sharp methyls around δ 2.4 and a sharp aldehyde signal around δ 9.8).
  • 20
    • 84914382227 scopus 로고    scopus 로고
    • 5) δ 17.7 (C-14), 21.4 (C-12′), 24.4 (C-13′), 26.5 (C-8), 26.7 (C-11), 26.9 (C-15), 27.1 (C-12), 27.4 (C-13), 28.7 (C-2), 33.4 (C-10), 34.6 (C-9), 34.9 (C-3), 34.9 (C-10′), 39.9 [[Truncated]]
  • 21
    • 84914382226 scopus 로고    scopus 로고
    • 5) δ 20.2 (C-9), 21.3 (C-12′), 22.0 (C-2), 22.1 (C-15), 23.0 (C-14), 23.8 (C-13′), 26.8 (C-11′), 27.4 (C-12), 27.6 (C-13), 31.7 (C-9′), 34.0 (C-3), 36.7 (C-9), 39.3 (C-4), 39.6 (C-10), 43.7 (C-10′), 46.2 (C-7), [[Truncated]]

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.