Aberrant cytokine production by sezary syndrome patients: Cytokine secretion pattern resembles murine TH2 cells

Journal of Investigative Dermatology

Volumn 99, Issue 1, 1992, Pages 90-94

  Vowels, Benjamin R ^a   Cassin, Maureen ^a   Vonderheid, Eric C ^b   Rook, Alain H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; PRIORITY JOURNAL; SEZARY SYNDROME;

ANIMAL; CYTOKINES; HUMAN; IMMUNOGLOBULIN E; INTERFERON TYPE II; INTERLEUKIN-2; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; LYMPHOMA, T-CELL, CUTANEOUS; MICE; MONOCYTES; SEZARY SYNDROME; SKIN NEOPLASMS; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES;

EID: 0026769328     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12611877     Document Type: Article

References (40)

1. Toback A.C. Edelson R.L. Pathogenesis of cutaneous T-cell lymphoma Dermatol Clin 3 1985 605 614
2. Sterry W. Mielke V. CD4+ cutaneous T cell lymphomas show the phenotype of helper/inducer T cells (CD45RA-,CDw29+) J Invest Dermatol 93 1989 413 416
3. Haynes B. Bunn P. Mann D. Cell surface differentiation antigens of the malignant T cell in Sezary syndrome and mycosis fungoides J Clin Invest 67 1981 523 530
4. Edelson R.L. Cutaneous T cell lymphoma: mycosis fungoides, Sezary syndrome, and other variants J Am Acad Dermatol 2 1980 89 106
5. Nickoloff B.J. Griffiths CEM. Baadsgaard O. Voorhees J.J. Hanson C.A. Cooper K.D. Markedly diminished epidermal keratinocyte expression of intercellular adhesion molecule-1 (ICAM-1) in Sezary syndrome JAMA 261 1989 2217 2221
6. Charley M.R. Chan L.J. Jegasothy B.V. Cytokine effect on cutaneous T-cell leukemia (CTCL) cells: specific proliferative response to IL-4 and IL-2 (abstr) J Invest Dermatol 94 1990 513
7. Yan S-L. Heald P. Latkowski J. Edelson R. Cytokine receptor expression on peripheral blood lymphocytes in Sezary syndrome (abstr) J Invest Dermatol 96 1991 611
8. Gaya A. de la Calle O. Yague J. Alsinet E. Fernandez M.D. Romero M. Fabregat V. Martorell J. Vives J. IL-4 inhibits IL-2 synthesis and IL-2-induced up-regulation of IL-2Rα but not IL-2Rβ chain in CD4+ human T cells J Immunol 146 1991 4209 4214
9. Welte K. Andreeff M. Platzer E. Interleukin 2 regulates the expression of TAC antigen on peripheral blood T lymphocytes J Exp Med 160 1984 1390 1403
10. Smith K.A. Cantrell D.A. Interleukin 2 regulates its own receptors Proc Natl Acad Sci USA 82 1985 864 868
11. Reem G.H. Yeh N. Interleukin 2 regulates expression of its receptor and synthesis of interferon-γ by human T lymphocytes Science 225 1984 429 430
12. Nagatani T. Matsuzaki T. Iemoto G. Kim S. Baba N. Miyamoto H. Nakajima H. Comparative study of cutaneous T-cell lymphoma and adult T-cell leukemia/lymphoma. Clinical, histopathologic, and immunohistochemical analyses Cancer 66 1990 2380 2386
13. Vercelli D. Jabara H.H. Lauener R.P. Geha R.S. IL-4 inhibits the synthesis of IFN-gamma and induces the synthesis of IgE in human mixed lymphocyte cultures J Immunol 144 1990 570 573
14. Umetsu D.T. Jabara H.H. DeKruyff R.H. Abbas A.K. Abrams J.S. Geha R.S. Functional heterogeneity among human inducer T cell clones J Immunol 140 1988 4211 4216
15. Mosmann T.R. Cherwinski H. Bond M.W. Giedlen M.A. Coffman R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins J Immunol 136 1986 2348 2357
16. Rotteveel FTM. Kokkelink I. vanLier RAW. Kuenen B. Meager A. Miedema F. Lucas C.J. Clonal analysis of functionally distinct human CD4+ T cell subsets J Exp Med 168 1988 1659 1673
17. Wierenga E.A. Snoek M. DeGroot C. Chretien I. Bos J.D. Jansen H.M. Kapsenberg M.L. Evidence for compartmentalization of functional subsets of CD4+ lymphocytes in atopic patients J Immunol 144 1990 4651 4656
18. Rousset F. Slierendregt B. Aubry J. Bonnefoy J. DeFrance T. Banchereau J. DeVries J.E. Regulation of Fc receptor for IgE (CD23) and class II MHC antigen expression on Burkitt's lymphoma cell lines by human IL-4 and IFN-gamma J Immunol 140 1988 2625 2632
19. Del Prete G. Maggi E. Parronchi P. Chretien I. Tiri A. Macchia D. Ricci M. Banchereau J. De Vries J. Romagnani S. IL-4 is an essential factor for the IgE synthesis induced in vitro by human T cell clones and their supernatants J Immunol 140 1988 4193 4198
20. Speigelberg H.L. Fc receptors for IgE and interleukin-4 induced IgE and IgG4 secretion J Invest Dermatol 94 1990 49 52
21. Rousset F. Billaud M. Blanchard D. Figdor C. Lenoir G.M. Spits H. DeVries J.E. IL-4 induces LFA-1 and LFA-3 expression on Burkitt's lymphoma cell lines J Immunol 143 1989 1490 1498
22. Hu-Li J. Shevach E.M. Mizuguchi J. Ohara J. Mosmann T. Paul W.E. B cell stimulatory factor-1 (interleukin 4) is a potent costimulant for normal resting T lymphocytes J Exp Med 165 1987 157 172
23. Peleman R. Wu J. Rargeas C. Delespesse G. Recombinant interleukin 4 suppresses the production of interferon gamma by human mononuclear cells J Exp Med 170 1989 1751 1756
24. Essner R. Rhoades K. McBride W.H. Morton D.L. Economou J.S. IL-4 down-regulates IL-1 and TNF gene expression in human monocytes J Immunol 142 1989 3857 3861
25. TeVelde A.A. Klomp JPG. Yard B.A. DeVries J.E. Figdor C.G. Modulation of phenotypic and functional properties of human peripheral blood monocytes by IL-4 J Immunol 140 1988 1548 1554
26. Gerrard T.L. Dyer D.R. Mostowski H.S. IL-4 and granulocyte-macrophage colony-stimulating factor selectively increases HLA-DR and HLA-DP antigens but not HLA-DQ antigens on human monocytes J Immunol 144 1990 4670 4674
27. Kawakami Y. Custer M.C. Rosenberg S.A. Lotze M.T. IL-4 regulates IL-2 induction of lymphokine-activated killer activity from human lymphocytes J Immunol 142 1989 3452 3461
28. Rook A.H. Kehrl J.H. Wakefield L.M. Effects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness J Immunol 136 1986 3916 3920
29. Schoenbeck S. McKenzie D.T. Kagnoff M.F. Interleukin 5 is a differentiation factor for IgA B cells Eur J Immunol 19 1989 965 969
30. Sanderson C.J. O'Garra A. Warren D.J. Klaus GGB. Eosinophil differentiation factor also has B-cell growth factor activity: proposed name interleukin 4 Proc Natl Acad Sci USA 83 1986 437 440
31. Lopez A.F. Sanderson C.J. Gamble J.R. Campbell H.D. Young I.G. Vadas M.A. Recombinant human interleukin 5 is a selective activator of human eosinophil function J Exp Med 219 1988 219 224
32. Fiorentino D.F. Bond M.W. Mosmann T.R. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones J Exp Med 170 1989 2081 2095
33. Gajewski T.F. Fitch F.W. Anti-proliferative effect of IFNγ in immune regulation. 1. IFNγ inhibits the proliferation of TH2 but not TH1 murine HTL clones J Immunol 140 1988 4245 4252
34. McLean J. Feliciani C. Rosenthal D. Christophers E. Sticherling M. Schroder J.M. Sauder D.N. Interleukin 8 immunoreactivity in patients with cutaneous T cell lymphoma (abstr) J Invest Dermatol 94 1990
35. Tron V.A. Rosenthal D. Sauder D.N. Epidermal interleukin-1 is increased in cutaneous T-cell lymphoma J Invest Dermatol 90 1988 378 381
36. Standiford T.J. Strieter R.M. Chensue S.W. Westwick J. Kasahara K. Kunkel S.L. IL-4 inhibits the expression of IL-8 from stimulated human monocytes J Immunol 145 1990 1435 1439
37. Kaplan E.H. Rosen S.T. Norris D.B. Roenigk H.H. Saks S.R. Bunn P.A. Phase II study of recombinant human interferon gamma for treatment of cutaneous T-cell lymphoma J Natl Cancer Inst 82 1990 208 212
38. Martinez O.M. Gibbos R.S. Garovoy M.R. Aronson F.R. IL-4 inhibits IL-2 receptor expression and IL-2-dependent proliferation of human T cells J Immunol 144 1990 2211 2215
39. Nagler A. Lanier L.L. Phillips J.H. The effects of IL-4 on human natural killer cells. A potent regulator of IL-2 activation and proliferation J Immunol 141 1988 2349 2351
40. Coffman R.L. Carty J. A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-γ J Immunol 136 1986 949 954