Rational design of potent antagonists to the human growth hormone receptor

Science

Volumn 256, Issue 5064, 1992, Pages 1677-1680

  Fuh, Germaine ^a   Cunningham, Brian C ^a   Fukunaga, Rikiro ^b   Nagata, Shigekazu ^b   Goeddel, David V ^a   Wells, James A ^a  

^a GENENTECH INC   (United States)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MURINAE;

GROWTH HORMONE DERIVATIVE; GROWTH HORMONE RECEPTOR; HUMAN GROWTH HORMONE; HYBRID PROTEIN;

ARTICLE; CELL GROWTH; DIMERIZATION; DRUG DESIGN; HUMAN; LEUKEMIA CELL; MYELOID LEUKEMIA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTIBODIES, MONOCLONAL; CELL DIVISION; CELL LINE; DNA REPLICATION; DOSE-RESPONSE RELATIONSHIP, DRUG; GROWTH HORMONE; HUMAN; MODELS, MOLECULAR; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; RECEPTORS, SOMATOTROPIN; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 0026764441     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.256.5064.1677     Document Type: Article

References (0)