Mechanisms of the stereoselective interaction between miconazole and racemic warfarin in human subjects

Clinical Pharmacology & Therapeutics

Volumn 51, Issue 6, 1992, Pages 656-667

  O'Reilly, Robert A ^a,b,c   Goulart, Darklis A ^a,b,c   Kunze, Kent L ^a,b,c   Neal, John ^a,b,c   Gibaldi, Milo ^a,b,c   Eddy, A Craig ^a,b,c   Trager, William F ^a,b,c  

^a SANTA CLARA VALLEY MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 ISOENZYME; MICONAZOLE; WARFARIN;

ADULT; ARTICLE; DRUG DISTRIBUTION; DRUG HYDROXYLATION; DRUG METABOLISM; ENZYME INHIBITION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RACEMIC MIXTURE; STEREOISOMERISM; STEREOSPECIFICITY;

ADULT; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; FEMALE; HALF-LIFE; HUMAN; HYDROXYLATION; KINETICS; MALE; MICONAZOLE; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; PROTHROMBIN TIME; STEREOISOMERISM; SUPPORT, U.S. GOV'T, P.H.S.; WARFARIN;

EID: 0026763432     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.1992.78     Document Type: Article

References (0)