5-Chlorolevulinate Modification of Porphobilinogen Synthase Identifies a Potential Role for the Catalytic Zinc

Biochemistry

Volumn 31, Issue 7, 1992, Pages 2113-2123

  Jaffe, Eileen K ^a   Abrams, William R ^b   Kaempfen, Henry X ^b   Harris, Kenneth A ^b  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; PORPHOBILINOGEN SYNTHASE; ZINC;

ARTICLE; BINDING SITE; CATALYSIS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME INACTIVATION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; ANIMAL; CATALYSIS; CATTLE; HYDROLYSIS; LEVULINIC ACIDS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; PEPTIDE MAPPING; PORPHOBILINOGEN SYNTHASE; SOMATOSTATIN; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; ZINC;

EID: 0026762499     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00122a032     Document Type: Article

References (31)

1. Barnard, G.F., Itoh, R., Hohberger, L.H., & Shemin, D. (1977) J. Biol. Chem. 252, 8965-8974.
2. Bevan, D.R., Bodlaender, P., & Shemin, D. (1980) J. Biol. Chem. 256, 2030-2035.
3. Bidlingmeyer, B.A., Cohen, S.A., & Tarvin, T.L. (1984) J. Chromatogr. 336, 93-104.
4. Bishop, T.R., Frelin, L.P., & Boyer, S.H. (1986) Nucleic Acids Res. 14, 10115.
5. Bishop, T.R., Hodes, Z.I., Frelin, L.P., & Boyer, S.H. (1989) Nucleic Acids Res. 17, 1775.
6. Bloxham, D.P., & Chalkley, R.A. (1976) Biochem. J. 159, 201-211.
7. Boese, Q.F., Spano, A.J., Li, J., & Timko, M.P. (1991) J. Biol. Chem. 266, 17060-17066.
8. Casen, J. (1955) in Organic Synthesis, Collect. Vol. II, pp 169-171, John Wiley & Sons, New York.
9. Christianson, D.W., & Lipscomb, W.N. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 7568-7572.
10. deBoer, T.J., & Backer, H.J. (1963) in Organic Synthesis, Collect. Vol. 4, pp 250-253, John Wiley & Sons, New York.
11. Dent, A.J., Beyersmann, D., Block, C., & Hasnain, S.S. (1990) Biochemistry 29, 7822-7828.
12. Echelard, Y., Dymetryszyn, J., Drolet, M., & Sasarman, A. (1988) Mol. Gen. Genet. 214, 503-508.
13. Granick, S., & Mauzerall, D. (1958) J. Biol. Chem. 232, 1119-1140.
14. Jaffe, E.K., & Hanes, D. (1986) J. Biol. Chem. 261, 9348-9353.
15. Jaffe, E.K., & Markham, G.D. (1987) Biochemistry 26, 4258-4264.
16. Jaffe, E.K., & Rajagopalan, J.S. (1990) Bioorg. Chem. 18, 381-394.
17. Jaffe, E.K., Salowe, S.P., Chen, N.T., & Dehaven, P. (1984) J. Biol. Chem. 259, 5032-5036.
18. Jaffe, E.K., Markham, G.D., & Rajagopalan, J.S. (1990) Biochemistry 29, 8345-8350.
19. Jordan, P.M., & Seehra, J.S. (1980) J. Chem. Soc., Chem. Commun., 240-242.
20. Li, J.M., Russell, C.S., & Cosloy, S.D. (1989) Gene 75 (1), 177-184.
21. Means, G.E., & Feeney, R.E. (1990) Bioconjugate Chem. 1, 2-12.
22. Myers, A.M., Crivellone, M.D., Koerner, T.J., & Tzagoloff, A. (1987) Biol. Chem. 262, 16822-16829.
23. Nandi, D.L., & Shemin, D. (1968) J. Biol. Chem. 243, 1236-1242.
24. Pappin, D.J.C., Coull, J.M., & Koester, H. (1990) in Current Research in Protein Chemistry. Techniques, Structure & Function, New Approaches to Covalent Sequence Analysis (Villafranca, J.J., Ed.) pp 191-202, Academic Press, New York.
25. Penning, T.M., Abrams, W.R., & Paulowski, J.E. (1991) J. Biol. Chem. (in press).
26. Seehra, J.S., & Jordan, P.M. (1981) Eur. J. Biochem. 113, 435-446.
27. Schoellmann, G., & Shaw, E. (1963) Biochemistry 2, 252-255.
28. Shemin, D., & Russell, C.S. (1953) J. Am. Chem. Soc. 75, 4873.
29. Smith, D.J., Maggio, E.T., & Kenyon, G.L. (1975) Biochemistry 14, 766-771.
30. Vallee, B.L., & Auld, D.S. (1990) Biochemistry 29, 5647-5659.
31. Wetmer, J.G., Bishop, D.F., Cantelmo, C., & Desnick, R.J. (1987) Proc. Natl. Acad. Sci. U.S.A. 83, 7703-7707.