Evidence for a bioactive clonidine-displacing substance in peripheral tissues and serum

Biochemical Pharmacology

Volumn 44, Issue 4, 1992, Pages 733-740

  Meeley, Mary P ^a   Hensley, Martee L ^a   Ernsberger, Paul ^a   Felsen, Diane ^a   Reis, Donald J ^b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Departments of Surgery ^*

Author keywords

[No Author keywords available]

Indexed keywords

CLONIDINE; CLONIDINE DISPLACING SUBSTANCE;

ADRENAL GLAND; ANIMAL TISSUE; ARTICLE; BRAIN; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SERUM; STOMACH FUNDUS; TISSUE DISTRIBUTION;

ADRENAL GLANDS; ADRENALECTOMY; ANIMAL; BRAIN CHEMISTRY; CLONIDINE; GASTRIC FUNDUS; MALE; MUSCLE CONTRACTION; RADIOIMMUNOASSAY; RATS; RATS, INBRED STRAINS; TISSUE EXTRACTS; VERAPAMIL;

EID: 0026758117     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(92)90410-K     Document Type: Article

References (28)

1. Isolation and partial purification of a clonidine-displacing endogenous brain substance
2. An endogenous clonidine-displacing substance from bovine brain: Receptor binding and hypotensive actions in the ventrolateral medulla
3. Raised levels of an endogenous nonadrenergic substance in the serum of pregnancy-induced hypertension patients
4. Neuroblastomaglioma hybrid cells contain clonidine-displacing substance
5. A specific antiserum recognizes clonidine-displacing substance: Implications for the structure of the brain's own clonidine
6. 2-adrenergic receptor binding sites: Implications for the structure of clonidine-displacing substance
7. Clonidine-specific antisera recognize an endogenous clonidine-displacing substance in brain
8. Clonidine-displacing substance is biologically active on smooth muscle
9. An endogenous clonidine-displacing substance (CDS) in brain elicits a pharmacologically unique contractile response in the gastric fundus
10. Clonidine-displacing substance is present in peripheral tissues of the rat
11. 2-adrenoceptors of human platelets
12. Platelet-activating factor is a potent stimulus for renal prostaglandin synthesis: Possible significance in unilateral ureteral obstruction
13. Fetal adrenal VIP: Distribution and effect on medullary catecholamine secretion
14. The distribution of vasoactive intestinal peptide in the rat adrenal cortex and medulla
15. Vasoactive intestinal peptide as a neural mediator of gastric relaxation
16. An endogenous, non-catecholamine clonidine antagonist increases mean arterial blood pressure
17. Imidazoline-guanidinium receptive site in renal proximal tubule: Asymetric distribution, regulation by cations and interaction with an endogenous clonidine displacing substance
18. + transport and intracellular pH in renal proximal tubule cells
19. Clonidine-displacing substance from bovine brain binds to imidazoline receptors and releases catecholamines in adrenal chromaffin cells
20. The imidazoline-preferring receptor
21. Imidazole receptors and their endogenous ligand in the rostral ventrolateral medulla: Relationship to the action of clonidine on arterial pressure
22. An endogenous substance with clonidine-like properties: Selective binding to imidazole sites in the ventrolateral medulla
23. 2-adrenoceptors and imidazoline binding sites: Distribution of imidazoline binding sites in rat brain
24. Characterization and visualization ofclonidine-sensitive imidazole sites in rat kidney which recognize clonidine-displacing substance
25. 2-adrenoceptors?
26. Subcellular distribution of imidazoline-guanidinium-receptive sites in human and rabbit liver
27. 2-adrenergic binding sites
28. Are there multiple imidazoline binding sites?