Rationally Designed “Dipeptoid” Analogues of CCK. A Free-Wilson/Fujita-Ban Analysis of Some α-Methyltryptophan Derivatives as CCK-B Antagonists

Journal of Medicinal Chemistry

Volumn 35, Issue 9, 1992, Pages 1572-1577

  Higginbottom, Michael ^a   Kneen, Clare ^a   Ratcliffe, Giles S ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ DERIVATIVE; CHOLECYSTOKININ RECEPTOR BLOCKING AGENT; N METHYLTRYPTOPHAN; TRYPTOPHAN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CHEMICAL STRUCTURE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; ENTROPY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMAL; CEREBRAL CORTEX; CHOLECYSTOKININ; DRUG DESIGN; MALE; MICE; MODELS, MOLECULAR; RECEPTORS, CHOLECYSTOKININ; THERMODYNAMICS; TRYPTOPHAN;

EID: 0026753127     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00087a011     Document Type: Article

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