Lipid Composition in Synaptic and Nonsynaptic Mitochondria from Rat Brains and Effect of Aging

Journal of Neurochemistry

Volumn 59, Issue 2, 1992, Pages 487-491

  Ruggiero, F M ^a   Cafagna, F ^a   Petruzzella, V ^a   Gadaleta, M N ^a   Quagliariello, E ^a  

^a CNR   (Italy)

Author keywords

Aging; Lipids; Mitochondria; Rat brain; Synaptosomes

Indexed keywords

CHOLESTEROL; FATTY ACID; PHOSPHOLIPID;

AGED; AGING; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN MITOCHONDRION; CELL MEMBRANE; CHOLESTEROL BLOOD LEVEL; ENDOCYTOSIS; JUVENILE; LIPID BILAYER; LIPID COMPOSITION; MALE; MATURITY; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ANALYSIS; SYNAPTIC MEMBRANE; SYNAPTIC POTENTIAL;

AGING; ANIMAL; BRAIN; BRAIN CHEMISTRY; CHOLESTEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMPARATIVE STUDY; FATTY ACIDS; LIPIDS; MALE; MITOCHONDRIA; PHOSPHOLIPIDS; RATS; RATS, INBRED F344; SUPPORT, NON-U.S. GOV'T; SYNAPSES;

ANIMALIA;

EID: 0026752775     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.1992.tb09396.x     Document Type: Article

References (33)

1. A rapid method of total lipid extraction and purification
2. A rapid method for the preparation of relatively pure metabolically competent synaptosomes from rat brain
3. Precursors for cholesterol synthesis (7‐dehydrocholesterol, 7‐dehydrodesmosterol, and desmosterol): cholesterol/7‐dehydrocholesterol ratio as an index of development and aging in PNS but not in CNS
4. Factors influencing the lipid composition and fluidity of red cell membranes in vitro: production of red cells possessing more than two cholesterol per phospholipids
5. The function of sterols in membranes
6. Rat brain synaptosomes prepared by phase partition
7. Inhibitors as probes of mitochondrial adenosine triphosphatase
8. Effect of cholesterol content on some physical and functional properties of mitochondria isolated from adult rat liver, fetal liver, cholesterol enriched liver and hepatomas AH‐130, 3924A and 5123
9. Reduced synthesis of mtRNA in isolated mitochondria of senescent rat brain
10. Reduced transcription of mitochondrial DNA in the senescent rat. Tissue dependence and effect of acetyl‐L‐carnitine
11. Age‐related changes in respiration coupled to phosphorylation. II. Cardiac mitochondria
12. Developing rat brain: changes in cholesterol, galactolipids, and the individual fatty acids of gangliosides and glycerophosphatides
13. Asymmetric distribution of phospholipids in the inner membrane of beef heart mitochondria
14. Preparation and properties of mitochondria derived from synaptosomes
15. The effect of cholesterol and other intercalated amphipaths on the contour and stability of the isolated red cell membrane
16. The activities of some energy‐metabolising enzymes in nonsynaptic (free) and synaptic mitochondria derived from selected brain regions
17. Protein measurement with the Folin phenol reagent
18. Microdetermination of phosphorus
19. Molecular basis of age‐dependent changes in activity of adenine nucleotide translocase
20. Studies on 2′,3′‐cyclic nucleotide‐3′‐phosphohydrolase from brain
21. Age‐related changes in the activity of the pyruvate carrier and in the lipid composition in rat‐heart mitochondria
22. Enhanced activity of the tricarboxylate carrier and modification of lipids in hepatic mitochondria from hyperthyroid rats
23. Effect of aging on the activity of the phosphate carrier and on the lipid composition in rat liver mitochondria
24. Alteration of plasma erythrocyte membrane lipid components in hyperthyroid rats
25. Lipid composition of liver mitochondria and microsomes in hyperthyroid rats
26. Effect of hypothyroidism on the lipid composition of rat plasma and erythrocyte membranes
27. Effect of aging and acetyl‐L‐carnitine on the lipid composition of rat plasma and erythrocytes
28. Microscopic radioautography of adult rat brain cholesterol. Problem of the blood‐brain barrier
29. Cholesterol transfer between brain and plasma in the rat: a model for the turnover of cerebral cholesterol
30. Lipid compositions of different regions of the human brain during aging
31. Ageassociated changes in rat plasma lipids, platelet fatty acids and prostacyclin release
32. Phospholipids and biomembranes
33. Diphosphatidylglycerol is required for optimal activity of beef heart cytochrome c oxidase