Synthesis and Antiviral Activity of Acyclic Nucleosides with a 3(S),5-Dihydroxypentyl or 4(R)-Methoxy-3(S),5-dihydroxypentyl Side Chain

Journal of Medicinal Chemistry

Volumn 35, Issue 8, 1992, Pages 1458-1465

  Vandendriessche, Frank ^a   Snoeck, Robert ^a   Janssen, Gerard ^a   Hoogmartens, Jos ^a   Van Aerschot, Arthur ^a   De Clercq, Erik ^a   Herdewijn, Piet ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2 DEOXYRIBOSE; 9 (2,3 DIHYDROXYPROPYL)ADENINE; 9 (3 HYDROXYPROPOXY)GUANINE; 9 [3 HYDROXY 2 (HYDROXYMETHYL)PROPOXY]GUANINE; ACICLOVIR; ACYCLIC NUCLEOSIDE; BUCICLOVIR; GANCICLOVIR;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HELA CELL; HERPES; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VERO CELL;

ANTIVIRAL AGENTS; MICROBIAL SENSITIVITY TESTS; NUCLEOSIDES; SIMPLEXVIRUS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T;

EID: 0026747732     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00086a015     Document Type: Article

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