Simultaneous insulinlike growth factor I and insulin resistance in obese Zucker rats

Diabetes

Volumn 41, Issue 6, 1992, Pages 691-697

  Jacob, Ralph J ^a,b   Sherwin, Robert S ^a   Greenawalt, Kathleen ^a   Shulman, Gerald I ^a  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; INSULIN; LACTIC ACID; SOMATOMEDIN C;

AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HORMONE ACTION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; LEAN BODY WEIGHT; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT;

AGING; AMINO ACIDS; ANIMAL; BLOOD GLUCOSE; BODY WEIGHT; COMPARATIVE STUDY; GLUCOSE CLAMP TECHNIQUE; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; OBESITY; RATS; RATS, ZUCKER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026740625     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.41.6.691     Document Type: Article

References (42)

1. Jacob R, Barrett E, Plewe G, Fagin K, Sherwin RS: Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat: comparison with insulin. J Clin Invest 83:1717-23, 1989
2. Zapf J, Hauri C, Waldvogel M, Froesch ER: Acute metabolic effects and half-lives of intravenously administered insulin-like growth factors I and II in normal and hypophysectomized rats. J Clin Invest 77:1768-75, 1986
3. Guler HP, Zapf J, Froesch ER: Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. N Engl J Med 317:137-40, 1987
4. Hill DJ, Crace CJ, Strain AJ, Milner RDG: Regulation of amino acid uptake and deoxyribonucleic acid synthesis in isolated human fetal fibroblasts and myoblasts: effect of human placental lactogen, somatomedin-C, multiplication-stimulating activity, and insulin. J Clin Endocrinol & Metab 62:753-60, 1986
5. Sasaoka T, Kobayashi M, Takata Y, Ishibashi O, Iwasaki M, Shigeta Y, Goji K, Hisatomi A: Clarification of signaling pathways mediated by insulin and insulin-like growth factor I receptors in fibroblasts from patients with specific defect in insulin receptor. Diabetes 37:1515-23, 1988
6. Yu K, Czech MP: The type I insulin-like growth factor receptor mediates the rapid effects of multiplication-stimulating activity on membrane transport systems in rat soleus muscle. J Biol Chem 259:3090-95, 1984
7. Jacob RJ, Sherwin RS, Bowen L, Fryburg D, Fagin KD, Tamborlane WV, Shulman GI: Metabolic effects of IGF-I and insulin in the spontaneously diabetic BB/w rat. Am J Physiol 260:E262-68, 1991
8. Giacca A, Gupta R, Efendic S, Hall K, Skottner A, Lickley L, Vranic M: Differential effects of IGF-I and insulin on glucoregulation and fat metabolism in depancreatized dogs. Diabetes 39:340-47, 1990
9. Rossetti L, Frontoni S, Dimarchi R, DeFronzo RA, Giaccari A: Metabolic effects of IGF-I in diabetic rats. Diabetes 40:444-48, 1991
10. DeFronzo RA, Simonson D, Ferrannini E: Hepatic and peripheral insulin resistance: a common feature in non-insulin dependent and insulin dependent diabetes. Diabetologia 23:313-19, 1982
11. Poggi C, Le Marchand-Brustel Y, Zapf J, Froesch ER, Freychet P: Effects of binding of insulin-like growth factor I in the isolated soleus muscle of lean and obese mice: comparison with insulin. Endocrinology 105:723-30, 1979
12. Garvey WT, Huecksteadt TP, Matthaei S, Olefsky JM: Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus. J Clin Invest 81:1528-36, 1988
13. Crettaz M, Prentki M, Zaninetti D, Jeanrenaud B: Insulin resistance in soleus muscle from obese Zucker rats. Biochem J 186:525-34, 1980
14. Caro JF, Sinha MK, Raju SM, Ittoop O, Pories WJ, Flickinger EG, Meelheim D, Dohm GL: Insulin receptor kinase in human skeletal muscle from obese subjects with and without noninsulin dependent diabetes. J Clin Invest 79:1330-37, 1987
15. Kolterman OG, Gray RS, Griffin J, Bernstein P, Insel J, Scarlett JA, Olefsky JM: Receptor and post receptor defects contribute to the insulin resistance in non-insulin-dependent diabetes mellitus. J Clin Invest 68:957-69, 1981
16. Mahmood HA, Wood PJ, Marks V: The effect of induced hyper-glucagonaemia on the Zucker fatty rat. Diabetologia 14:405-12, 1978
17. Dohm GL, Elton CW, Raju MS, Mooney ND, DiMarchi R, Pories WJ, Flickinger EG, Atkinson SM Jr, Caro JF: IGF-I-stimulated glucose transport in human skeletal muscle and IGF-I resistance in obesity and NIDDM. Diabetes 39:1028-32, 1990
18. Cascieri MA, Slater EE, Vicario PP, Green BG, Bayne ML, Saperstein R: Impaired insulin-like growth factor I-mediated stimulation of glucose incorporation into glycogen in vivo in the ob/ob mouse. Diabetologia 32:342-47, 1989
19. Livingston JN, Pollare T, Kithell H, Arner P: Characterization of insulin-like growth factor I receptor in skeletal muscles of normal and insulin resistant subjects. Diabetologia 31:871-77, 1988
20. Zucker LM, Zucker TF: Fatty, a new mutation in the rat. J Hered 52:275-78, 1961
21. Stern JS, Johnson PR, Greenwood MRC, Zucker LM, Hirsch J: Insulin resistance and pancreatic insulin release in the genetically obese Zucker rat. Proc Soc Exp Biol Med 139:66-69, 1972
22. Zucker LM, Antoniades . Insulin and obesity in the Zucker genetically obese rat "fatty." Endocrinology 90:1320-30, 1972
23. Stern JS, Johnson PR, Batchelor BR, Zucker LM, Hirsch J: Pancreatic insulin release and peripheral tissue resistance in Zucker obese rats fed high- and low-carbohydrate diets. Am J Physiol 228:543-48, 1975
24. Ionescu E, Sauter JF, Jeanrenaud B: Abnormal oral glucose tolerance in genetically obese (fa/fa) rats. Am J Physiol 248:E500-506, 1985
25. Terrettaz J, Jeanrenaud B: In vivo hepatic and peripheral insulin resistance in genetically obese (fa/fa) rats. Endocrinology 112: 1346-51, 1983
26. Smith D, Rossetti L, Ferrannini E, Johnson CM, Cobelli C, Toffalo G, Katz LD, DeFronzo RA: In vivo glucose metabolism in the awake rat tracer and insulin clamp studies. Metab Clin Exp 36:1167-74, 1987
27. Rossetti L, Smith D, Shulman GI, Papachristou D, DeFronzo RA: Correction of hyperglycemia with Phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest 79:1510-15, 1987
28. Caro JF, Ittoop O, Pories Wj, Meelheim D, Flickinger EG, Thomas F, Jenquin M, Silverman JF, Khazanie PG, Sinha MK: Studies on the mechanism of insulin resistance in the liver from humans with noninsulin-dependent diabetes. J Clin Invest 78:249-58, 1986
29. Meuli C, Froesch ER: Insulin and nonsuppressible insulin-like activity (NSILA-S) stimulate the same glucose transport system via two separate receptors in rat heart. Biochem Biophys Res Commun 75:689-95, 1977
30. Zorzano A, James DE, Ruderman NB, Pilch PF: Insulin-like growth factor I binding and receptor kinase in red and white muscle. FEBS Lett 234:257-62, 1988
31. Wallberg-Henriksson H, Galuska D, Thorne A, Sonnenfeld: Metformin increases insulin-stimulated glucose transport in insulin-resistant human skeletal muscle (Abstract). In Glucophage Symposium Helsingor, 1990, p. 43
32. Matthaei S, Reibold JP, Klein HH, Benecke H, Hamann A, Greten H: Effect of in vivo Metformin-treatment on insulin binding, glucose transport, activation of insulin receptor kinase in intact cells, and subcellular distribution of GLUT-1 and GLUT-4 glucose transporters in adipocytes from obese (fa/fa) Zucker rats (Abstract). In Proc Annu Meet Endocrinol Soc, 72nd, Atlanta, GA, 1990, p. 46
33. Sowell MO, Robinson KA, Buse MG: Phenylarsine oxide and denervation effects on hormone-stimulated glucose transport. Am J Physiol 255:E159-65, 1988
34. Bray GA: Studies on the composition of adipose tissue from the genetically obese rats. Proc Soc Exp Biol Med 131:1111-14, 1969
35. Johnson PR, Zucker LM, Cruce JAF, Hirsch J: Cellularity of adipose depots in the genetically obese Zucker rat. J Lipid Res 12:706-14, 1971
36. Stern JS, Greenwood MRC: A review of development of adipose cellularity in man and animals. Fed Proc 33:1952-55, 1974
37. Randle PJ, Garland PB, Newsholme EH, Hales CM: The glucose fatty acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1:785-89, 1963
38. Bounder J, Lindblad A, Engfeldt P, Arner P: Studies of acute effects of insulin-like growth factors I and II in human fat cells. J Clin Endocrinol Metab 65:732-37, 1987
39. Sinha MK, Buchanan C, Reneri C, Khazanie P, Pories WJ, DiMarchi R, Caro JF: IGF-I-stimulated glucose transport, IGF-I receptors and tyrosine kinase are not altered as noted for insulin in adipocytes from NIDDM patients (Abstract). Diabetes 38 (Suppl. 1):103A, 1989
40. Finkelstein JA, Chance WT, Fischer JE: Brain serotonergic activity and plasma amino acid levels in genetically obese Zucker rats. Pharmacol Biochem Behav 17:939-44, 1982
41. Tsuda TT, Ohkubo T, Kamiguchi H, Tsuda M, Katsunuma T, Yamamura M: Influence of fecal anorexigenic substance (FS-T) on plasma amino acids in Wistar and Zucker obese (fa/fa) rats. J Nutr 119:1327-32, 1989
42. DeFronzo RA: Glucose intolerance and aging: evidence for tissue insensitivity to insulin. Diabetes 28:1095-1101, 1979