Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro

Journal of Biological Chemistry

Volumn 267, Issue 28, 1992, Pages 20352-20362

  Sampath, T K ^a   Maliakal, J C ^a   Hauschka, P V ^a   Jones, W K ^a   Sasak, H ^a   Tucker, R F ^a   White, K H ^a   Coughlin, J E ^a   Tucker, M M ^a   Pang, R H L ^a   Corbett, C ^a   Ozkaynak, E ^a   Oppermann, H ^a   Rueger, D C ^a  

^a CURIS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; ANTIBODY; CYCLIC AMP; GROWTH FACTOR; OSTEOCALCIN; PARATHYROID HORMONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MATRIX; CELL COUNT; CELL CULTURE; CELL DENSITY; CELL DIFFERENTIATION; CELL GROWTH; COLLAGEN SYNTHESIS; ENZYME ACTIVITY; HISTOCHEMISTRY; HORMONE ACTION; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PURIFICATION; PROTEIN SYNTHESIS; RADIOIMMUNOASSAY; RAT; SKULL;

ALKALINE PHOSPHATASE; AMINO ACID SEQUENCE; ANIMAL; BLOTTING, WESTERN; CATTLE; CHO CELLS; COMPARATIVE STUDY; CYCLIC AMP; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INDUCTION; HAMSTERS; HUMAN; MOLECULAR SEQUENCE DATA; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; PARATHYROID HORMONES; PROTEINS; RATS; RECOMBINANT PROTEINS; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFORMING GROWTH FACTOR BETA;

BOVINAE; HUMULUS; MAMMALIA;

EID: 0026739256     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)