Application of Neural Networks: Quantitative Structure-Activity Relationships of the Derivatives of 2,4-Diamino-5-(substituted-benzyl)pyrimidines as DHFR Inhibitors

Journal of Medicinal Chemistry

Volumn 35, Issue 17, 1992, Pages 3201-3207

  So, Sung Sau ^a   Richards, W Graham ^a  

^a Physical Chemistry Laboratory   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINOPYRIMIDINE DERIVATIVE; DIHYDROFOLATE REDUCTASE; DIHYDROFOLATE REDUCTASE INHIBITOR;

ARTICLE; COMPUTER ANALYSIS; COMPUTER SIMULATION; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; NERVE CELL NETWORK; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REGRESSION ANALYSIS; THEORY;

COMPARATIVE STUDY; DRUG DESIGN; FOLIC ACID ANTAGONISTS; NEURAL NETWORKS (COMPUTER); PYRIMIDINES; REGRESSION ANALYSIS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0026738394     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00095a016     Document Type: Article

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