Antifungal cyclic peptides from the terrestrial blue-green alga anabaena laxa: I. Isolation and biological properties

The Journal of Antibiotics

Volumn 45, Issue 9, 1992, Pages 1451-1457

  Frankmolle, Walter P ^a   Larsen, Linda K ^a   Caplan, Faith R ^a   Patterson, Gregory M L ^a   Knubel, Georg ^a   Levine, Ira A ^a   Moore, Richard E ^a  

^a UNIVERSITY OF HAWAII   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; CYCLOPEPTIDE; LAXAPHYCIN; LAXAPHYCIN A; LAXAPHYCIN B; LAXAPHYCIN C; LAXAPHYCIN D; LAXAPHYCIN E; UNCLASSIFIED DRUG;

ANABAENA; ANTIFUNGAL ACTIVITY; ARTICLE; BLUE GREEN ALGA; CYANOBACTERIUM; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENTIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL;

ANTIBIOTICS, ANTIFUNGAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYANOBACTERIA; DRUG SYNERGISM; FUNGI; MICROBIAL SENSITIVITY TESTS; PEPTIDES, CYCLIC; SUPPORT, U.S. GOV'T, NON-P.H.S.;

EID: 0026736820     PISSN: 00218820     EISSN: 18811469     Source Type: Journal    
DOI: 10.7164/antibiotics.45.1451     Document Type: Article

References (11)

1. Chmel, H. & D. B. Louria: Antifungal antibiotics: Mechanism of action, resistance, susceptibility testing, and assays of activity in biological fluids. In Antibiotics in Laboratory Medicine. Ed., V. Lorian, pp. 170-192, Williams & Wilkins, 1980
2. Hallander, H. O.; K. Dornbusch, L. Gezelius, K. Jacobson & I. Karlsson: Synergism between aminoglycosides and cephalosporins with antipseudomonal activity: Interaction index and killing curve method. Antimicrob. Agents Chemother. 22: 743-752, 1982
3. Hoeprich, P. D. & P. D. Finn: Obfuscation of the activity of antifungal antimicrobics by culture media. J. Infect. Dis. 126: 353-361, 1972
4. Shadomy, S.: In vitro studies with 5-fiuorocytosine. Appl. Microbiol. 17: 871-877, 1969
5. Medoff, G.; M. Comfort & G. S. Kobayashi: Synergistic action of amphotericin B and 5-fluorocytosine against yeast-like organisms. Proc. Soc. Exp. Biol. Med. 138: 571-574, 1971
6. Lehrer, R. I.; D. Szklarek, T. Ganz & M. E. Selsted: Synergistic activity of rabbit granulocyte peptides against Candida albicans. Infect. Immun. 52: 902-904, 1986
7. Ennis, H. L.: Synergistin: A synergistic antibiotic complex which selectively inhibits protein synthesis. In Progress in Antimicrobial & Anticancer Chemotherapy Proceedings of the 6th International Congress Chemotherapy Volume 2. pp. 489-498, University of Tokyo Press, 1970
8. Allen, M. B.: The cultivation of myxophyceae. Arch. Mikrobiol. 17: 34-53, 1952
9. Shadomy, S.; A. Espinel-Ingroff & R. Y. Cartwright: Laboratory studies with antifungal agents: Susceptibility tests and bioassays. In Manual of Clinical Microbiology. 4th Ed. Ed., E. H. Lennette et ah, pp. 991-999, American Society Microbiology, 1985
10. Patterson, G. M. L.; C. L. Baldwin, C. M. Bolis, F. R. Caplan, H. Karuso, L. K. Larsen, I. A. Levine, R. E. Moore, C. S. Nelson, K. D. Tschappat, G. D. Tuang, E. Furusawa, S. Furusawa, T. R. Norton & R. B. Raybourne: Antineoplastic activity of cultured blue-green algae (cyanophyta). J. Phycol. 27: 530-536, 1991
11. Kitahara, M.; V. K. Seth, G. Medoff & G. S. Kobayashi: Antimicrobial susceptibility testing of six clinical isolates of Aspergillus. Antimicrob. Agents Chemother. 9: 908-914, 1976