In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. I. Effects on androgenic status

Toxicology and Applied Pharmacology

Volumn 114, Issue 1, 1992, Pages 97-107

  Mably, Thomas A ^a   Moore, Robert W ^a   Peterson, Richard E ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ANDROSTANOLONE; TESTOSTERONE;

ADOLESCENT; ANDROGEN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYPTORCHISM; FEMALE; FETUS; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MALE GENITAL SYSTEM; NEWBORN; NONHUMAN; PERINATAL DRUG EXPOSURE; PHYSICAL DEVELOPMENT; PRENATAL DRUG EXPOSURE; PRIMIGRAVIDA; PRIORITY JOURNAL; PROSTATE; RAT; SEMINAL VESICLE; SEXUAL DEVELOPMENT; TESTOSTERONE BLOOD LEVEL;

ANIMAL; ANIMALS, NEWBORN; BODY WEIGHT; BREAST FEEDING; FEMALE; GENITALIA, MALE; LUTEINIZING HORMONE; MALE; ORGAN WEIGHT; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; SUPPORT, U.S. GOV'T, P.H.S.; TESTOSTERONE; TETRACHLORODIBENZODIOXIN; TIME FACTORS;

ANIMALIA;

EID: 0026736617     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/0041-008X(92)90101-W     Document Type: Article

References (42)

1. Light and electron microscopic observations in Macaca mulatta monkeys fed toxic fat
2. Response of chickens to prolonged feeding of crude “toxic fat”
3. Ontogeny of hypothalamic luteinizing hormone-releasing hormone (GnRH) and pituitary GnRH receptors in fetal and neonatal rats
4. Sex differentiation of cyclic gonadotropin secretion
5. 2,3,7,8-Tetrachlorodibenzo-p-dioxin increases the potency of androgens and estrogens as feedback inhibitors of luteinizing hormone secretion in male rats
6. Reproductive toxicity and pharmacokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin. 1. Effects of high doses on the fertility of male rats
7. Differences among rat sex accessory glands in their neonatal androgen dependency
8. Neonatal imprinting of the accessory sex glands and hepatic monooxygenases in adulthood
9. Androgen action and the sex accessory tissues
10. On some alternative procedures using ranks for the analysis of experimental designs
11. Teratology studies with 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin
12. Differential sensitivity of rat accessory-sex-tissues to androgen following neonatal castration or androgen treatment
13. The neuroendocrine regulation of sexual behavior
14. Specificity of neonatal, androgen-induced imprinting of hepatic steroid metabolism in rats
15. Polychlorodibenzo-p-dioxins: Perinatal effects and the dominant lethal test in Wistar rats
16. Inhibition of testicular steroidogenesis in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats: Evidence that the key lesion occurs prior to or during pregnenolone formation
17. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD): Results of a 13-week oral toxicity study in rats
18. In utero and lactational exposure of male rats to 2,3,8,8-tetrachlorodibenzo-p-dioxin. 3. Effects on spermatogenesis and reproductive capability
19. In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 2. Effects on sexual behavior and the regulation of luteinizing hormone secretion in adulthood
20. Effects of perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on pre- and postnatal plasma testosterone (T) concentrations in male rats
21. Relative toxicity of chlorinated dibenzo-p-dioxins, and dibenzofurans measured by thymus weight and liver enzyme induction in perinatally dosed rats, 2,3,7,8-TCDD, 2,3,4,7,8-PeCDF, 1,2,3,7,8-PeCDD
22. The comparative toxicity of chlorinated dibenzo-p-dioxins in mice and guinea pigs
23. Depression of rat testicular 17-hydroxylase and 17,20-lyase after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
24. 14C]tetrachlorodibenzo-p-dioxin in pregnant and neonatal rats
25. Plasma concentrations of pituitary hormones in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated male rats
26. Androgen catabolism and excretion in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats
27. Androgenic deficiency in male rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
28. Aspects of androgen-dependent events as studied by antiandrogens
29. Fetal toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the rat and hamster
30. The stimulation of steroid biosynthesis by luteinizing hormone
31. Effects of neonatal steroids on male sex tissues
32. Hormonal regulation of testicular descent: Experimental and clinical observations
33. Effects of age and season on sexual behavior and plasma testosterone and dihydrotestosterone concentrations of laboratory-housed male rhesus monkeys (Macaca mulatta)
34. Study of the teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the rat
35. Hormonal control of spermatogenesis
36. Transfer of polychlorinated dibenzo-p-dioxins and dibenzofurans to fetal and neonatal rats
37. Increased incidence of neoplasms in rats exposed to low levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin
38. Suppression of cellular immunity in rats and mice by maternal treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin
39. The effect of gonadotrophins on the fetal and neonatal rat testis
40. Ontogeny of gonadotropin receptors in the fetal and neonatal rat testis