Telomere end-replication problem and cell aging

Journal of Molecular Biology

Volumn 225, Issue 4, 1992, Pages 951-960

  Levy, Michael Z ^a   Allsopp, Richard C ^a   Futcher, A Bruce ^b   Greider, Carol W ^b   Harley, Calvin B ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

cell kinetics; chromosomes; DNA replication; fibroblasts; senescence

Indexed keywords

EUKARYOTA;

SINGLE STRANDED DNA;

ADULT; ARTICLE; CELL AGING; CELL CYCLE; CELL DIVISION; CELL GROWTH; CHROMOSOME REPLICATION; CHROMOSOME STRUCTURE; DNA CONTENT; DNA REPLICATION; FIBROBLAST; GROWTH REGULATION; HUMAN; HUMAN CELL; HYPOTHESIS; MALE; PRIORITY JOURNAL; RESTRICTION FRAGMENT; SENESCENCE; TELOMERE;

ADULT; BASE SEQUENCE; CELL DIVISION; CELLS, CULTURED; CHROMOSOME DELETION; CHROMOSOMES, HUMAN; DNA; DNA REPLICATION; FIBROBLASTS; HUMAN; KINETICS; MODELS, GENETIC; OLIGONUCLEOTIDE PROBES; REPETITIVE SEQUENCES, NUCLEIC ACID; SKIN PHYSIOLOGY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TELOMERE;

EID: 0026735646     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-2836(92)90096-3     Document Type: Article

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