Structure-function analysis of hepatocyte growth factor: Identification of variants that lack mitogenic activity yet retain high affinity receptor binding

EMBO Journal

Volumn 11, Issue 7, 1992, Pages 2503-2510

  Lokker, N A ^a   Mark, M R ^a   Luis, E A ^a   Bennett, G L ^a   Robbins, K A ^a   Baker, J B ^a   Godowski, P J ^a  

^a GENENTECH INC   (United States)

Author keywords

c Met proto oncogene; Hepatocyte growth factor; Hepatocyte growth factor receptor; Mutagenesis; Structure function study

Indexed keywords

GROWTH FACTOR; GROWTH FACTOR RECEPTOR; PROTEIN PRECURSOR; SCATTER FACTOR; SERINE PROTEINASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING KINETICS; CONTROLLED STUDY; DELETION MUTANT; DNA SYNTHESIS; HUMAN; LIVER CELL CULTURE; MITOGENICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN VARIANT; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALIA;

EID: 0026734672     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1992.tb05315.x     Document Type: Article

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