A Nonpromoting Phorbol from the Samoan Medicinal Plant Homalanthus Nutans Inhibits Cell Killing by HIV-1

Journal of Medicinal Chemistry

Volumn 35, Issue 11, 1992, Pages 1978-1986

  Gustafson, Kirk R ^a,b,c,d,e   Cardellina, John H ^a,b,c,d,e   McMahon, James B ^a,b,c,d,e   Gulakowski, Robert J ^a,b,c,d,e   Ishitoya, Junichi ^a,b,c,d,f   Szallasi, Zoltan ^a,b,c,d,f   Lewin, Nancy ^a,b,c,d,f   Blumberg, Peter ^a,b,c,d,f   Weislow, Owen S ^a,b,c,d,g   Beutler, John A ^a,b,c,d,g   Buckheit, Robert W ^a,b,c,d   Cragg, Gordon M ^a,b,c,d,h   Cox, Paul A ^a,b,c,d   Bader, John P ^a,b,c,d,i   Boyd, Michael R ^a,b,c,d,e  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SOUTHERN RESEARCH INSTITUTE   (United States)

^d BRIGHAM YOUNG UNIVERSITY   (United States)

^e Brigham Young University ^*  (United States)

^f Executive Plaza North ^*  (United States)

^g Laboratory of Drug Discovery Research Development ^*  (United States)

^h American Society of Pharmacognosy   (United States)

ⁱ Dyncorp/Program Resources Inc ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 DEOXYPHORBOL DERIVATIVE; PROSTRATIN; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CELL PROTECTION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG ISOLATION; ENZYME BINDING; HOMALANTHUS NUTANS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOBLASTOID CELL; MACROPHAGE; MEDICINAL PLANT; MONOCYTE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SAMOAN ISLANDS; TUMOR PROMOTION;

ANIMAL; CELL LINE; CELL SURVIVAL; CYTOPATHOGENIC EFFECT, VIRAL; EDEMA; HIV-1; HUMAN; HYPERPLASIA; INDEPENDENT STATE OF SAMOA; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MONOCYTES; ORNITHINE DECARBOXYLASE; PHORBOL ESTERS; PLANTS, MEDICINAL; PROTEIN KINASE C; SKIN; SUPPORT, U.S. GOV'T, NON-P.H.S.; T-LYMPHOCYTES; VIRUS REPLICATION;

EID: 0026734304     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00089a006     Document Type: Article

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