Synthesis and Evaluation of Analogues of (Z)-1-(4-Methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as Potential Cytotoxic and Antimitotic Agents

Journal of Medicinal Chemistry

Volumn 35, Issue 12, 1992, Pages 2293-2306

  Cushman, Mark ^a   Nagarathnam, Dhanapalan ^a   Gopal, D ^a   He, Hu Ming ^a   Lin, Chii M ^b   Hamel, Ernest ^b  

^a PURDUE UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,4,4',5 TETRAMETHOXYSTILBENE; ANTIMITOTIC AGENT; BENZOPHENONE DERIVATIVE; BENZYLISOQUINOLINE DERIVATIVE; CINNAMIC ACID DERIVATIVE; COLCHICINE; COMBRETASTATIN A4; CYTOTOXIC AGENT; DOXORUBICIN; PHENANTHRENE DERIVATIVE; PODOPHYLLOTOXIN; PROTOBERBERINE DERIVATIVE; STILBENE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN MCF 7; COLON CANCER; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MELANOMA CELL; MICROTUBULE ASSEMBLY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL DIVISION; COLONIC NEOPLASMS; COMPARATIVE STUDY; HUMAN; LUNG NEOPLASMS; MELANOMA; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0026734208     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00090a021     Document Type: Article

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