A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues

Proceedings of the National Academy of Sciences of the United States of America

Volumn 89, Issue 16, 1992, Pages 7370-7374

  Cortopassi, G A ^a   Shibata, D ^a   Soong, N W ^a   Arnheim, N ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Brain; Degenerative disease; Heart; PCR; Somatic mutation

Indexed keywords

MITOCHONDRIAL DNA;

ADOLESCENT; ADULT; AGED; AGING; ARTICLE; AUTOPSY; BRAIN CORTEX; CHILD; CLINICAL ARTICLE; DIAPHRAGM; FEMALE; GENE DELETION; GENE MUTATION; HEART LEFT VENTRICLE; HUMAN; HUMAN TISSUE; KIDNEY; LIVER; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SKIN; SPLEEN; STOCHASTIC MODEL;

ADOLESCENT; ADULT; AGED; AGING; CHILD, PRESCHOOL; CHROMOSOME DELETION; DNA DAMAGE; DNA, MITOCHONDRIAL; HUMAN; MIDDLE AGE; ORGAN SPECIFICITY; POLYMERASE CHAIN REACTION; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026732706     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.89.16.7370     Document Type: Article

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