Antigen processing and presentation in the Eye: A review

Current Eye Research

Volumn 11, Issue S1, 1992, Pages 49-58

  Liversidge, Janet ^a   Forrester, John V ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPAIN; CATHEPSIN B; CHYMOSTATIN; EPITOPE; INTERPHOTORECEPTOR RETINOID BINDING PROTEIN; LEUPEPTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPSTATIN; PEPTIDE; PHOSPHORAMIDON; PLASMIN; PROSTAGLANDIN E2; PROTEINASE INHIBITOR; RETINA S ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; AUTOIMMUNITY; CELLULAR IMMUNITY; CONFERENCE PAPER; EYE; IMMUNE RESPONSE; IMMUNOREACTIVITY; IMMUNOTHERAPY; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; PIGMENT EPITHELIUM; UVEORETINITIS;

ANIMAL; ANTIGEN-PRESENTING CELLS; ANTIGENS; ARRESTIN; AUTOANTIGENS; EYE PROTEINS; HISTOCOMPATIBILITY ANTIGENS CLASS II; LYMPHOCYTE ACTIVATION; RATS; RATS, INBRED LEW; RECEPTORS, ANTIGEN, T-CELL; RETINOL-BINDING PROTEINS; SUPPORT, NON-U.S. GOV'T; T-LYMPHOCYTES;

EID: 0026728183     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.3109/02713689208999511     Document Type: Review

References (34)

1. S-antigen: structure, function and experimental autoimmune uveitis (EAU)
2. Identification of an immunodominant and highly immunopathogenic determinant in the retinal protein interphotoreceptor retinoid binding protein (IRBP)
3. Identification of a potent new pathogenic site in human retinal S-antigen which induces experimental autoimmune uveitis in LEW rats
4. Repeated determinants within the retinal interphotoreceptor retinoid-binding protein (IRBP): Immunological properties of the repeats of an immunodominant determinant
5. The choice of T cell epitopes utilised on a protein antigen depends on multiple factors distant from, as well as at the determinant site
6. Structure function studies of S-antigen: use of proteases to reveal a dominant uveitogenic site
7. The effect of retinal S-antigenspecific monoclonal antibody therapy on experimental autoimmune uveoretinitis (EAU) and experimental autoimmune pinealitis (EAP)
8. Selective inhibition of antigen presentation to cloned T cells by protease inhibitors
9. Identification and characterisation of a new potent, pathogenic proliferative, S-antigen T cell site with retricted Vβ8 and Vα2 specificity
10. Purification and characterisation of a retinol binding glycoprotein synthesised and secreted by bovine, neural retina
11. IRBP induced EAU: an immunophenotypic analysis using APAAP, dual fluorescence (DIF) and confocal microscopy
12. The Vβ-specific superantigen staphylococcal enterotoxin B: stimulation of mature T cells and clonal deletion in neonatal mice
13. Segregation of MHC class II molecules from MHC class I molecules in the golgi complex for transport to lysosomal compartments
14. Receptor-mediated antigen uptake and its effect on antigen presentation to class II restricted T lymphocytes
15. Proteolytic enzymes
16. Dissociation between lymphocyte activation for proliferation and for the capacity to adoptively transfer uveoretinitis
17. The T cell repertoire to a multi determinate antigen
18. Distinct accessory cell requirements define two types of rat T cell hybridomas specific for unique determinants in the encephalitogenic 68–86 region of myelin basic protein
19. 2-dependent induction of B cell unresponsiveness
20. Recognition of peptides that are immunopathogenic but cryptic
21. Dual effect of cilliary body cells on T lymphocyte proliferation
22. Immunoregulatory properties of bone marrow-derived cells in the iris and ciliary body
23. Analysis of immunosuppressive properties of iris and ciliary body cells and their secretory products
24. Glial retinal Müller cells produce IL-1 activity and have a dual effect on autoimmune T helper lymphocytes
25. Electron immunocytochemical localisation of retinal S-antigen with a rat monoclonal antibody
26. Interactions between lymphocytes and cells of the blood-retina barrier: mechanisms of T lymphocyte adhesion to retinal capillary endothelial cells and retinal pigment epithelial cells in vitro
27. Are accessory molecules implicated in activation of T cells at the blood-retina barrier
28. Regulation of the local immune response by retinal cells
29. 2
30. Remote T cell co-stimulation via LFA-1/ICAM-1 and CD2/LFA-3: demonstration with immobilised ligand/mAb and implication in monocyte mediated co-stimulation
31. Constitutive competition by self proteins for antigen presentation can be overcome by receptor-enhanced uptake
32. The autoimmune T cell receptor: epitopes idiotopes and maletopes
33. Peptide specific prevention of experimental allergic encephalomyelitis: neonatal tolerance induced to the dominant T cell determinant of myelin basic protein