Appearance of interleukin-1 in macrophages and in ramified microglia in the brain of endotoxin-treated rats: a pathway for the induction of non-specific symptoms of sickness?

Brain Research

Volumn 588, Issue 2, 1992, Pages 291-296

  van Dam, Anne Marie ^a   Brouns, Madeleine ^a   Louisse, Simone ^a   Berkenbosch, Frank ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Brain; Endotoxin; Interleukin 1; Macrophage; Microglia; Perivascular cell; Sickness

Indexed keywords

ENDOTOXIN; INTERLEUKIN 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; MACROPHAGE; MALE; MICROGLIA; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; BRAIN; ENDOTOXINS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; MACROPHAGES; MALE; NEUROGLIA; RATS; RATS, WISTAR; SUPPORT, NON-U.S. GOV'T;

EID: 0026726031     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(92)91588-6     Document Type: Article

References (22)

1. Control of brain endothelial permeability
2. Neuroendocrinology of interleukin-1
3. Interleukin-1 in the central nervous system: a role in the acute phase response and in brain injury, brain development and the pathogenesis of Alzheimer's disease
4. Stress and immunity: an integrated view of the relationships between the brain and the immune system
5. Selective depletion of macrophages prevents pituitary-adrenal activation in response to subpyrogenic, but not to pyrogenic, doses of bacterial endotoxin in rats
6. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3
7. Neuroimmunological mechanisms in cerebral amyloid deposition in Alzheimer's disease
8. 6 glioma cells
9. Synthesis of interleukin-1/endogenous pyrogen in the brain of endotoxin-treated mice: a step in fever induction?
10. Identity of ED2-positive perivascular cells in rat brain
11. Ameboid microglia as effectors of inflammation in the central nervous system
12. Biological basis of the behavior of sick animals
13. Brain macrophages synthesize interleukin-1 and interleukin-1 mRNAs in vitro
14. Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
15. Sickness behavior as a new target for drug development
16. Presence of cytokines in the hypothalamic-pituitary axis
17. Function and mechanisms of interleukin-1 in the brain
18. A new technique for studying specificity of immunocytochemical procedures
19. Immunohistochemical techniques for light-microscopical localization of dopamine, noradrenaline, adrenaline, serotonin and histamine in the central nervous system
20. An improved staining method for rat microglia glial cells using the lectin from Griffonia simplicifolia (GSA I-B4)
21. Immunological study of the glial fibrillary acidic protein