The bone morphogenetic protein family and osteogenesis

Molecular Reproduction and Development

Volumn 32, Issue 2, 1992, Pages 160-167

  Wozney, John M ^a  

^a PFIZER INC   (United States)

Author keywords

BMP; Bone; TGF beta superfamily

Indexed keywords

MESSENGER RNA; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; BONE DEFECT; BONE DEVELOPMENT; CHONDROGENESIS; CONFERENCE PAPER; CONTROLLED STUDY; DOG; DROSOPHILA; EMBRYO DEVELOPMENT; IN SITU HYBRIDIZATION; LIMB BUD; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PURIFICATION; RAT; SHEEP;

ANIMAL; BONE MORPHOGENETIC PROTEINS; EMBRYO AND FETAL DEVELOPMENT; GROWTH SUBSTANCES; HUMAN; OSTEOGENESIS; PROTEINS;

ANIMALIA; CANIS FAMILIARIS; MAMMALIA; OVIS ARIES; RODENTIA;

EID: 0026721147     PISSN: 1040452X     EISSN: 10982795     Source Type: Journal    
DOI: 10.1002/mrd.1080320212     Document Type: Article

References (27)

1. Identification of transforming growth factor β family members present in bone‐inductive protein purified from bovine bone
2. Histological and ultrastructural comparison of the in vivo activities of rhBMP‐2 and rhBMP‐5
3. Purification, characterization and activities of recombinant bone morphogenetic protein 5
4. Healing of large mid‐femoral segmental defects in sheep using recombinant human bone morphogenetic protein (BMP‐2)
5. Bone‐inducing activity of mature BMP‐2b produced from a hybrid BMP‐2a/2b precursor
6. Involvement of Bone Morphogenetic Protein‐4 (BMP‐4): and Vgr‐1 in morphogenesis and neurogenesis in the mouse
7. Osteogenic protein‐1 (OP‐1): stimulates proliferation and differentiation of human bone cells (HBC): in vitro
8. Purification and partial amino acid sequence of osteogenin, a protein initiating bone differentiation
9. Vgr‐1, a mammalian gene related to Xenopus Vg‐1, is a member of the transforming growth factor β gene superfamily
10. Patterns of expression of murine Vgr‐1 and BMP‐2a RNA suggest that transforming growth factor‐β‐like genes coordinately regulate aspects of embryonic development
11. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein‐2A (BMP‐2A)
12. OP‐1 cDNA encodes an osteogenic protein in the TGF‐β family
13. Cell biology and biochemistry of endochondral bone development
14. Expression of osteoblast‐like phenotype in mouse embryo limb bud cell lines cultured in BMP‐2 and retinoic acid
15. Purification and molecular cloning of a novel group of BMPs and localization of BMP mRNA in developing bone
16. Bovine osteogenic protein is composed of dimers of OP‐1 and BMP‐2A, two members of the transforming growth factor‐β superfamily
17. Recombinant human osteogenic protein (hOP‐1): induces new bone formation with a specific activity comparable to that of natural bovine osteogenic protein
18. Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation
19. Recombinant human bone morphogenetic protein‐2 induces osteoblastic differentiation in W‐20‐17 stromal cells
20. Mandibular reconstruction with a recombinant bone‐inducing factor
21. Bone: Formation by autoinduction
22. Solubilized and insolubilized bone morphogenetic protein
23. Purification and characterization of other distinct bone‐inducing factors
24. Recombinant human bone morphogenetic protein induces bone formation
25. Novel regulators of bone formation: Molecular clones and activities
26. Recombinant human bone morphogenetic protein‐2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro
27. Recombinant BMP‐2a bone induction in a rat orthotopic model