The influence of ebselen on the toxicity of cisplatin in LLC-PK1 cells

Biochemical Pharmacology

Volumn 44, Issue 2, 1992, Pages 382-387

  Baldew, Glenn S ^a,b   Boymans, Antonius P ^a   Mol, Johannes G J ^b   Vermeulen, Nico P E ^b  

^a Interuniversity Reactor Institute Delft   (Netherlands)

^b NONE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; EBSELEN; LACTATE DEHYDROGENASE; PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; CELL PROTECTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; AZOLES; CELL LINE; CELL SURVIVAL; CISPLATIN; COMPARATIVE STUDY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; KIDNEY; LACTATE DEHYDROGENASE; ORGANOSELENIUM COMPOUNDS; RATS; SWINE; TIME FACTORS;

EID: 0026716075     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(92)90024-D     Document Type: Article

References (37)

1. Toxic effects of cisdichlorodiammine platinum in man
2. Attenuation of cisplatinum-induced nephrotoxicity in the rat by high salt diet, furosemide and acetazolamide
3. Renal and electrolyte disturbances associated with cisplatin
4. cis-Diamminedichloroplatinum(-II)-induced acute renal failure in the rat. Correlation of structural and functional alterations
5. The nephrotoxicity of cisplatin
6. Characterization of the reactions of platinum antitumor agents with biologic and nonbiologic sulfur-containing nucleophiles
7. Methods of reduction of cisplain nephrotoxicity
8. High-dose cisplatin in hypertonic saline
9. High-dose cisplatin with sodium thiosulfate protection
10. Effect of diethyldithiocarbamate on cis-diamminedichloroplatinum(II)-induced cytotoxicity, DNA cross-linking and γ-glutamyltranspeptidase inhibition
11. High-dose carboplatin with diethyldithiocarbamate chemoprotection in treatment of women with relapsed ovarian cancer
12. Seleno-organic compounds and the therapy of hydroperoxide-linked pathological conditions
13. Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ 51)
14. Mechanism of the reaction of ebselen with endogenous thiols
15. Isolated proximal tubular cells from rat kidney as an in vitro model for studies on nephrotoxicity. II. α-Methylglucose uptake as a sensitive parameter for mechanistic studies of acute toxicity by xenobiotics
16. 1 and MDCK)
17. Comparative toxicity of aminoglycoside antibiotics in cell cultures derived from human and pig kidney
18. 1 cell
19. 1 cells as a model for cis-diamminedichloroplatinum(II) nephrotoxicity and modulation by thiol rescue agents
20. 195Pt]-labeled antitumor drug, cis-dichloro-diammineplatinum(II), cis-DDP
21. Determination of cisplatin and related platinum complexes in plasma ultrafiltrate and urine by high-performance liquid chromatography with on-line radioactivity detection
22. Protein measurement with the Folin phenol reagent
23. Cisplatin nephrotoxicity: physiological and biochemical aspects
24. Mechanisms of cytotoxicity of anticancer platinum drugs: evidence that cis-diamminedichloroplatinum(II) and cis-diammine( 1,1 -cyclobutanedicarboxylato)platinum(II) differ only in the kinetics of their interaction with DNA
25. The mechanism of action of antitumor platinum compounds
26. Selective reduction of cis-diamminedichloroplatinum (II) nephrotoxicity by ebselen
27. 1): a model system for aminoglycoside nephrotoxicity
28. Selective protection against cis-diamminedichloroplatinum(II)-induced toxicity in kidney, gut and bone marrow by diethyldithiocarbamate
29. Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid
30. Reduction of cisplatin nephrotoxicity by selenium does metallothionein play a role?
31. Selenium-induced protection against cis-diamminedichloroplatinum (II) nephrotoxicity in mice and rats
32. Selenium efficiently depressed toxic side effect of cis-diamminedichloroplatinum
33. Optimum schedule of selenium administration to reduce lethal and renal toxicities of cis-diamminedichloroplatinum in mice
34. The mechanism of interaction between cisplatin and selenite