Post‐Transcriptional regulationa of collagenase and stromelysin gene expression by epidermal growth factor and dexamethasone in cultured human fibroblasts

Journal of Cellular Biochemistry

Volumn 50, Issue 4, 1992, Pages 400-410

  Delany, Anne M ^a   Brinckerhoff, Constance E ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

DRB; glucocorticoid; half life; metalloproteinase; RNA stability

Indexed keywords

COLLAGENASE; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR; STROMELYSIN;

ARTICLE; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; MALE; NORMAL HUMAN; PREPUCE; PRIORITY JOURNAL; RNA SYNTHESIS;

BLOTTING, NORTHERN; CELLS, CULTURED; COLLAGENASES; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR; FIBROBLASTS; GENE EXPRESSION REGULATION; HALF-LIFE; HUMAN; MALE; METALLOENDOPEPTIDASES; RNA, MESSENGER; STROMELYSIN 1; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC;

EID: 0026714363     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.240500409     Document Type: Article

References (57)

1. Phorbol esterinducible genes contain a common cis element recognized by a TPA‐modulated trans‐acting factor
2. The AP‐1, sequence is necessary but not sufficient for phorbol induction of collagenase in fibroblasts
3. Prolonged activation of junand collagenase genes by tumor necrosis factor‐α
4. Regulation of c‐myc mRNA stability in vitro by a labile destalibizer with an essential nucleic acid component
5. An A+U‐rich element RNA ‐binding factor regulates c‐myc mRNA stability in vitro
6. Collagenase and rheumatoid arthritis: Regulation of collagenase synthesis by synovial cells
7. Half‐life synovial cell collagenase is modulated by phorbol myristate acetate but not by all ‐trans‐retinoic acid or dexamethasone
8. Molecular cloning of human synovial cell collagenase and selection of a single gene from genomic DNA
9. Epidermal growth factor
10. Epidermal growth factor
11. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
12. Differential regulation of the expression of proteinases/antiproteinases in fibroblasts. Effects of interleukin‐1 and platelet‐derived growth factor
13. Increase in levels of procollagenase messenger RNA in cultured fibroblasts induced by human recombinant interleukin 1 β or serum follow c‐jun expression and are dependent on new protein synthesis
14. Fos and jun: The AP‐1 connection
15. Variety in the level of gene control in eukaryotic cells
16. Protooncogene c‐fos as a trascription factor
17. Effect of epidermanl growth factor on the proliferation of human epithelial growth factor on the proliferation of human epithelial cancer cell line: Correlation with the level of occupied receptor
18. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor
19. A technique for radiolabeling restriction fragments to high specific activity
20. Cloning of a complementary DNA for rabit proactivator. A metalloproteinase that activates synovial cell collagenase, shares homology with stromelysin and transin, and is coordinately regulated with collagenase
21. Gene expression (collagenase, tissue inhibitor of metalloproteinases, complement, and HLA‐DR) in rheumatoid arthritis and osteoarthritis synovium. Quantitative analysis and effect of intraarticular corticosteroids
22. Transcription from the stromelysin promoter is induced by interleukin‐1 and repressed by dexamethasone
23. EGF receptor down regulation attenuates ligand‐induced second messenger formation
24. The adenosine‐uridine binding factor recognizes the AU‐rich elements of cytokine, lymphokine and oncogene mRNAs
25. Stimulation of 3T3 cells inbuced transcription of the c‐fos proto‐oncogene
26. The collagenase gene promoter contains a TPA and oncogene‐responsive unit encompassing the PEA‐3 and AP‐1 binding sites
27. Synthesis and degradation of type I collagen mRNA in cultured human skin fibroblasts and the effect of cortisol
28. Separate endocytic pathways of kinase‐defective and active EGF receptor mutants expressed in same cells
29. Antitumor promotion and antiinflammation: Down‐modulationof AP‐1 (Fos/Jun) activity by glucocorticoid hormone
30. Growth factors regulate transin gene expression by c‐fos‐dependent and c‐fos‐independent pathways
31. Interference between pathway‐specific transcription factors: Glucocorticoids antagonize phorbol ester‐induced AP‐1 activity without altering AP‐1 site occupation in vivo
32. Dissoordiante expression of stromelysin, collagenase and tissue inhibitor of metalloproteinases‐1 in rheumatiod human synovial fibroblasts. Synergistic effects of interleukin‐1 and tumor necrosis factor‐α on stromelysin expression
33. Identification of an AUUUA‐specific messenger RNA binding protein
34. A redox swith and phosphorylation are involved in the post‐translational up‐regulation of the adenosine‐uridine binding factor by phorbol ester and ionophore
35. Epidermanl growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts
36. Transcription and translation: A practical approach
37. Isolation of the oncogene and epidermal growth factor‐induced transin gene: Complex control in rat fibroblasts
38. Gorwth factor‐regulated proteases and extracellular matrix remodeling during mammalian development
39. Regulation of humna synovial firbroblast collagenase messenger RNA by interleukin‐1
40. Epidermal growth factor stimulation of stromelysion mRNA in rat fibroblasts requires induction of proto‐oncogenes c‐fos and c‐jun and activation of protein kinase C
41. Serum amyloid a (SAA3) produced by rabbit synovial fibroblasts treated with phorbol esters or interleukin 1 induces synthesis of collagenase and is neutralized by specific antiserum
42. Cycloheximide induces stromelysin mRNA in cultured human firbroblasts
43. The AU‐rich sequences in the 3′ untranslated region mediate the increased turnover mRNA induced by glucocortiocids
44. Transcriptional regulation of human stromelysin
45. Requirement of fos gene expression in the transcriptional activation of collagenase by other oncogense and phorbol ester
46. Functional antagonism between oncoprotein c‐Jun and the glucocorticoid receptor
47. A conserved AU sequence from the 3′ untranslated region of the GM‐CSF mRNA mediates selective mRNA degradation
48. Cloning of the genes for human stromelysin and stromelysin 2: Differential expression in rheumatoid synovial fibroblasts
49. Interleukin‐1 or phorbol induction of stromelysin promoter requires an element that competes with AP‐1
50. Activation of insulin‐epidermal growth (EGF) receptor chimerae regulated EGF receptor binding affinity
51. Jun: Oncogene and transcription factor
52. The c‐Ets oncoprotein activates the stromelysin promoter through the same elements as several non‐nuclear oncoproteins
53. Proteinases and matrix degradation
54. Comparison of human stromelysin and collagenase by cloning and sequence analysis
55. Human fibroblast stromelysin: Structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells
56. Transcriptional interference betweeen c‐Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct proteinprotein interaction