A highly selective δ1-opioid receptor antagonist: 7-benzylidenenaltrexone

European Journal of Pharmacology

Volumn 218, Issue 1, 1992, Pages 195-196

  Portoghese, P S ^b   Sultana, M ^b   Nagase, H ^b   Takemori, A E ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

7 Benzylidenenaltrexone (BNTX); Antinociception; Opioid receptor subtypes binding

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; 7 BENZYLIDENENALTREXONE; DELTA OPIATE RECEPTOR; DELTORPHIN II [2 DEXTRO ALANINE]; ENKEPHALIN DERIVATIVE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; ETHYLKETAZOCINE; LEUCINE ENKEPHALIN[2 DEXTRO SERINE 6 THREONINE]; MORPHINE; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; OPIATE ANTAGONIST; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG SELECTIVITY; GUINEA PIG; ILEUM; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; TAIL FLICK TEST; VAS DEFERENS;

ANIMAL; BENZYLIDENE COMPOUNDS; GUINEA PIGS; IN VITRO; NALTREXONE; NARCOTIC ANTAGONISTS; RECEPTORS, OPIOID, DELTA; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026710225     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(92)90167-3     Document Type: Article

References (8)

1. 6]enkephalin: Covalent attachment via thiol-disulfide exchange
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7. Role of spacer and address components in peptidomimetic δ opitoid receptor antagonists related to naltrindole
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